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WO1999039120B1 - Commande de fluide par expansion thermique de dispositifs microfluidiques - Google Patents

Commande de fluide par expansion thermique de dispositifs microfluidiques

Info

Publication number
WO1999039120B1
WO1999039120B1 PCT/US1999/001831 US9901831W WO9939120B1 WO 1999039120 B1 WO1999039120 B1 WO 1999039120B1 US 9901831 W US9901831 W US 9901831W WO 9939120 B1 WO9939120 B1 WO 9939120B1
Authority
WO
WIPO (PCT)
Prior art keywords
liquid fluid
liquid
fluid
reservoir
remotely
Prior art date
Application number
PCT/US1999/001831
Other languages
English (en)
Other versions
WO1999039120A1 (fr
Inventor
James P Landers
Andreas Huhmer
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/015,278 external-priority patent/US6210882B1/en
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Priority to AU23477/99A priority Critical patent/AU2347799A/en
Publication of WO1999039120A1 publication Critical patent/WO1999039120A1/fr
Publication of WO1999039120B1 publication Critical patent/WO1999039120B1/fr

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K13/00—Other constructional types of cut-off apparatus; Arrangements for cutting-off
    • F16K13/08—Arrangements for cutting-off not used
    • F16K13/10—Arrangements for cutting-off not used by means of liquid or granular medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B01L2300/1872—Infrared light

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention concerne un nouveau procédé de manipulation précise de volumes en picolitre-nanolitre dans des puces microfluidiques. La technique concerne l'expansion thermique d'un fluide, la pression et l'écoulement du fluide pouvant être facilement manipulées par régulation de la température du fluide. On peut appliquer efficacement de la chaleur de manière simple au moyen d'une source (30) lumineuse/infrarouge (par exemple une lampe halogène) qui chauffe sélectivement le fluide (36) dans la puce par absorption de l'énergie optique se trouvant dans la partie visible-infrarouge (VIS/IR) du spectre électromagnétique. On peut obtenir plusieurs applications de régulation et de manipulation de fluides sur des puces microfluidiques au moyen du mécanisme de pompe de fluide activé par VIS/IR, y compris une soupape.
PCT/US1999/001831 1998-01-29 1999-01-28 Commande de fluide par expansion thermique de dispositifs microfluidiques WO1999039120A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU23477/99A AU2347799A (en) 1998-01-29 1999-01-28 Thermal expansion-induced fluid control for microfluidic devices

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/015,278 1998-01-29
US09/015,278 US6210882B1 (en) 1998-01-29 1998-01-29 Rapid thermocycling for sample analysis
US16988698A 1998-10-12 1998-10-12
US09/169,886 1998-10-12

Publications (2)

Publication Number Publication Date
WO1999039120A1 WO1999039120A1 (fr) 1999-08-05
WO1999039120B1 true WO1999039120B1 (fr) 1999-09-16

Family

ID=26687173

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/001831 WO1999039120A1 (fr) 1998-01-29 1999-01-28 Commande de fluide par expansion thermique de dispositifs microfluidiques

Country Status (2)

Country Link
AU (1) AU2347799A (fr)
WO (1) WO1999039120A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001259770A1 (en) 2000-05-15 2001-11-26 Biomicro Systems, Inc. Air flow regulation in microfluidic circuits for pressure control and gaseous exchange
US6615856B2 (en) 2000-08-04 2003-09-09 Biomicro Systems, Inc. Remote valving for microfluidic flow control
DE10050943B4 (de) * 2000-10-10 2005-08-25 Epigenomics Ag Vorrichtung zur Hybridisierung von Proben an Arrays biologischer Stoffe
US7347976B2 (en) 2001-12-20 2008-03-25 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix
US7192560B2 (en) 2001-12-20 2007-03-20 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using anion exchange
DE10222228A1 (de) 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Mikropumpe mit Heizelementen für einen pulsierten Betrieb
FR2841158B1 (fr) * 2002-06-24 2007-02-23 Bio Merieux Dispositif fluidique permettant de maniere thermo-pneumatique l'isolement et eventuellement l'agitation du contenu d'une cavite operatoire
US7981600B2 (en) 2003-04-17 2011-07-19 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using an anion exchange material that includes a polyoxyalkylene
US7939249B2 (en) 2003-12-24 2011-05-10 3M Innovative Properties Company Methods for nucleic acid isolation and kits using a microfluidic device and concentration step
US7727710B2 (en) 2003-12-24 2010-06-01 3M Innovative Properties Company Materials, methods, and kits for reducing nonspecific binding of molecules to a surface
WO2005099901A1 (fr) * 2004-04-13 2005-10-27 Dtu Systeme de distribution d'echantillon microfluidique
US7913928B2 (en) 2005-11-04 2011-03-29 Alliant Techsystems Inc. Adaptive structures, systems incorporating same and related methods
EP1790861A1 (fr) * 2005-11-25 2007-05-30 Bonsens AB Système microfluidique
JP7653363B2 (ja) 2019-04-22 2025-03-28 ラム リサーチ コーポレーション 空間的に調節可能なウエハへのｒｆ結合を有する静電チャック
US12377416B2 (en) * 2020-10-09 2025-08-05 Hewlett-Packard Development Company, L.P. Reversible micro-valve devices
CN113357416B (zh) * 2021-06-29 2022-12-13 湖南八达人防科技股份有限公司 一种水封式回火防止机构

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4676274A (en) * 1985-02-28 1987-06-30 Brown James F Capillary flow control
JPH0610900A (ja) * 1992-04-27 1994-01-21 Canon Inc 液体移動方法及び移動装置ならびにこれを利用した測定装置
US5700695A (en) * 1994-06-30 1997-12-23 Zia Yassinzadeh Sample collection and manipulation method
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device

Also Published As

Publication number Publication date
AU2347799A (en) 1999-08-16
WO1999039120A1 (fr) 1999-08-05

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