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WO2000060119A3 - Technique permettant de detecter les cellules cancereuses - Google Patents

Technique permettant de detecter les cellules cancereuses Download PDF

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Publication number
WO2000060119A3
WO2000060119A3 PCT/US2000/008588 US0008588W WO0060119A3 WO 2000060119 A3 WO2000060119 A3 WO 2000060119A3 US 0008588 W US0008588 W US 0008588W WO 0060119 A3 WO0060119 A3 WO 0060119A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
cancer cells
cancer
detecting cancer
detecting
Prior art date
Application number
PCT/US2000/008588
Other languages
English (en)
Other versions
WO2000060119A2 (fr
Inventor
Thomas Ried
Jonathan Uhr
Bijan M Ghadimi
Evelin Schrock
Gert Auer
Original Assignee
Us Gov Health & Human Serv
Thomas Ried
Jonathan Uhr
Bijan M Ghadimi
Evelin Schrock
Gert Auer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv, Thomas Ried, Jonathan Uhr, Bijan M Ghadimi, Evelin Schrock, Gert Auer filed Critical Us Gov Health & Human Serv
Priority to AU40565/00A priority Critical patent/AU4056500A/en
Publication of WO2000060119A2 publication Critical patent/WO2000060119A2/fr
Publication of WO2000060119A3 publication Critical patent/WO2000060119A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne une bioanalyse hautement sensible permettant de distinguer les cellules épithéliales dans le sang cancéreuses et celles qui ne le sont pas. Cette invention apporte une technique diagnostique améliorée permettant de détecter le cancer et de déterminer l'organe à l'origine de ce cancer.
PCT/US2000/008588 1999-04-01 2000-03-31 Technique permettant de detecter les cellules cancereuses WO2000060119A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU40565/00A AU4056500A (en) 1999-04-01 2000-03-31 Methods for detecting cancer cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12736799P 1999-04-01 1999-04-01
US60/127,367 1999-04-01

Publications (2)

Publication Number Publication Date
WO2000060119A2 WO2000060119A2 (fr) 2000-10-12
WO2000060119A3 true WO2000060119A3 (fr) 2002-01-10

Family

ID=22429747

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/008588 WO2000060119A2 (fr) 1999-04-01 2000-03-31 Technique permettant de detecter les cellules cancereuses

Country Status (2)

Country Link
AU (1) AU4056500A (fr)
WO (1) WO2000060119A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7034144B2 (en) 1997-05-13 2006-04-25 Erasmus Universiteit Rotterdam Molecular detection of chromosome aberrations
US7105294B2 (en) 1998-05-04 2006-09-12 Dako Denmark A/S Method and probes for the detection of chromosome aberrations

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005028677A2 (fr) * 2003-05-07 2005-03-31 Agilent Technologies, Inc. Systemes et procedes permettant de determiner la composition d'un type de cellule d'une population cellulaire melangee a l'aide de signatures d'expression genique
WO2007021211A1 (fr) * 2005-08-15 2007-02-22 Evgeniya Stefanova Skobeltsina Methode permettant de diagnostiquer des maladies tumorales chez l'etre humain
KR20090071667A (ko) * 2006-10-25 2009-07-01 아이코니시스 인코포레이티드 암 및 고등급 과형성증의 자동화된 검출
US20090258365A1 (en) 2008-03-25 2009-10-15 Terstappen Leon W M M METHOD FOR DETECTING IGF1R/Chr 15 in CIRCULATING TUMOR CELLS USING FISH
DE102009059274B4 (de) * 2009-12-22 2012-07-19 Max-Joseph Kraus Verfahren zur Messung der Dynamik der Änderungen von Blutplättchen

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996002002A1 (fr) * 1994-07-08 1996-01-25 Schalken Jack A Analyse servant a deceler une augmentation du pouvoir envahissant de cellules epitheliales
WO1997038313A1 (fr) * 1996-04-05 1997-10-16 The Johns Hopkins University Procede d'enrichissement de cellules rares
WO1997046702A1 (fr) * 1996-06-03 1997-12-11 The Regents Of The University Of California Modifications genetiques associees au cancer de la prostate

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996002002A1 (fr) * 1994-07-08 1996-01-25 Schalken Jack A Analyse servant a deceler une augmentation du pouvoir envahissant de cellules epitheliales
WO1997038313A1 (fr) * 1996-04-05 1997-10-16 The Johns Hopkins University Procede d'enrichissement de cellules rares
WO1997046702A1 (fr) * 1996-06-03 1997-12-11 The Regents Of The University Of California Modifications genetiques associees au cancer de la prostate

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GHADMI B ET AL: "Specific chromosomal abberations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas", AMERICAN JOURNAL OF PATHOLOGY, vol. 154, no. 2, February 1999 (1999-02-01), pages 525 - 36, XP001024303 *
HESELMEYER-HADDAD K ET AL: "Interphase cytogenetics with tumor-stage specific probes for the detection of tumor progression in cervical and mammary carcinogenesis", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, vol. 40, March 1999 (1999-03-01), pages 537, XP001024240 *
HEYSELMEYER K ET AL: "advanced-stage cervical cancer are defined by a reurrent pattern of chromosomal abberations revealing high genetic instability and a consistent gain of chromosome arm 3q", GENES, CHROMOSOMES AND CANCERTIGATIONS, vol. 19, no. 4, 1997, pages 233 - 40, XP001024299 *
MAKAROVSKIY A N ET AL: "APPLICATION OF IMMUNOMAGNETIC BEADS IN COMBINATION WITH RT-PCR FOR THE DETECTION OF CIRCULATING PROSTATE CANCER CELLS", JOURNAL OF CLINICAL LABORATORY ANALYSIS, NEW YORK, NY, US, vol. 11, 1997, pages 346 - 350, XP000872241 *
RACILA E ET AL: "Detection and charcterization of carcinoma cells in the blood", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 95, April 1998 (1998-04-01), pages 4589 - 4594, XP002132943, ISSN: 0027-8424 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7034144B2 (en) 1997-05-13 2006-04-25 Erasmus Universiteit Rotterdam Molecular detection of chromosome aberrations
US7105294B2 (en) 1998-05-04 2006-09-12 Dako Denmark A/S Method and probes for the detection of chromosome aberrations
US7368245B2 (en) 1998-05-04 2008-05-06 Dako Denmark A/S Method and probes for the detection of chromosome aberrations
US7642057B2 (en) 1998-05-04 2010-01-05 Dako Denmark A/S Method and probes for the detection of chromosome aberrations

Also Published As

Publication number Publication date
WO2000060119A2 (fr) 2000-10-12
AU4056500A (en) 2000-10-23

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