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WO2000008169A8 - Dna sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants - Google Patents

Dna sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants

Info

Publication number
WO2000008169A8
WO2000008169A8 PCT/EP1999/005467 EP9905467W WO0008169A8 WO 2000008169 A8 WO2000008169 A8 WO 2000008169A8 EP 9905467 W EP9905467 W EP 9905467W WO 0008169 A8 WO0008169 A8 WO 0008169A8
Authority
WO
WIPO (PCT)
Prior art keywords
xylulose
overproduction
deoxy
plants
phosphate synthase
Prior art date
Application number
PCT/EP1999/005467
Other languages
German (de)
French (fr)
Other versions
WO2000008169A1 (en
Inventor
Andreas Reindl
Mejia Patricia Leon
Palmas Juan Manuel Esteves
Gracia Maria Araceli Cantero
Marcus Ebneth
Karin Herbers
Original Assignee
Sungene Gmbh & Co Kgaa
Andreas Reindl
Mejia Patricia Leon
Palmas Juan Manuel Esteves
Gracia Maria Araceli Cantero
Marcus Ebneth
Karin Herbers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1998135219 external-priority patent/DE19835219A1/en
Priority claimed from DE1998145224 external-priority patent/DE19845224A1/en
Priority claimed from DE1998145231 external-priority patent/DE19845231A1/en
Priority claimed from DE1998145216 external-priority patent/DE19845216A1/en
Application filed by Sungene Gmbh & Co Kgaa, Andreas Reindl, Mejia Patricia Leon, Palmas Juan Manuel Esteves, Gracia Maria Araceli Cantero, Marcus Ebneth, Karin Herbers filed Critical Sungene Gmbh & Co Kgaa
Priority to CA002339519A priority Critical patent/CA2339519A1/en
Priority to AU54157/99A priority patent/AU757440B2/en
Priority to EP99940083A priority patent/EP1102852A1/en
Priority to JP2000563793A priority patent/JP2002525034A/en
Publication of WO2000008169A1 publication Critical patent/WO2000008169A1/en
Publication of WO2000008169A8 publication Critical patent/WO2000008169A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Method for the production of plants with enhanced vitamin E biosynthesis efficiency by overproduction of a 1-deoxy-D-xylulose-5-phosphate synthase gene from Arabidopsis or E. coli.
PCT/EP1999/005467 1998-08-05 1999-07-30 Dna sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants WO2000008169A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002339519A CA2339519A1 (en) 1998-08-05 1999-07-30 Dna sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants
AU54157/99A AU757440B2 (en) 1998-08-05 1999-07-30 DNA sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants
EP99940083A EP1102852A1 (en) 1998-08-05 1999-07-30 Dna sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants
JP2000563793A JP2002525034A (en) 1998-08-05 1999-07-30 DNA sequence encoding 1-deoxy-D-xylulose-5-phosphate synthase and its overproduction in plants

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE1998135219 DE19835219A1 (en) 1998-08-05 1998-08-05 Use of 1-deoxy-D-xylulose-5-phosphate synthase DNA to produce plants with increased tocopherol, vitamin K, chlorophyll and/or carotenoid content
DE19845231.4 1998-10-01
DE1998145224 DE19845224A1 (en) 1998-10-01 1998-10-01 Use of DNA encoding 1-deoxy-D-xylulose-5-phosphate synthase to produce plants with increased tocopherol, vitamin K, chlorophyll and carotenoid content
DE19835219.0 1998-10-01
DE1998145231 DE19845231A1 (en) 1998-10-01 1998-10-01 Use of DNA encoding 1-deoxy-D-xylulose-5-phosphate synthase to produce plants with increased tocopherol, vitamin K, chlorophyll and carotenoid content
DE1998145216 DE19845216A1 (en) 1998-10-01 1998-10-01 Use of DNA encoding 1-deoxy-D-xylulose-5-phosphate synthase to produce plants with increased tocopherol, vitamin K, chlorophyll and carotenoid content
DE19845224.1 1998-10-01
DE19845216.0 1998-10-01

Publications (2)

Publication Number Publication Date
WO2000008169A1 WO2000008169A1 (en) 2000-02-17
WO2000008169A8 true WO2000008169A8 (en) 2000-05-04

Family

ID=27438844

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/005467 WO2000008169A1 (en) 1998-08-05 1999-07-30 Dna sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants

Country Status (5)

Country Link
EP (1) EP1102852A1 (en)
JP (1) JP2002525034A (en)
AU (1) AU757440B2 (en)
CA (1) CA2339519A1 (en)
WO (1) WO2000008169A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2325798C (en) 1998-04-14 2008-08-26 Kyowa Hakko Kogyo Co., Ltd. A process for producing isoprenoid compounds by microorganisms and a method for screening compounds with antibiotic or weeding activity
GB9901902D0 (en) * 1999-01-28 1999-03-17 New Royal Holloway & Bedford Manipulating isoprenoid expression
DE19903493A1 (en) * 1999-01-29 2000-08-03 Basf Ag Overexpression of a DNA sequence coding for a transketolase in plants
DE60034224T2 (en) 1999-04-15 2007-12-20 Calgene Llc, Davis NUCLEIC ACID SEQUENCES FOR PROTEINS INVOLVED IN ISOPRENOID SYNTHESIS
DE19937957A1 (en) * 1999-08-11 2001-02-15 Sungene Gmbh & Co Kgaa Homogenate dioxygenase
US20020072503A1 (en) * 2000-03-28 2002-06-13 Jiangchun Xu Compositions and methods for the therapy and diagnosis of ovarian cancer
US6632630B2 (en) 2000-03-29 2003-10-14 Aclara Biosciences, Inc. Monooxygenase assays
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
AR030430A1 (en) * 2000-06-29 2003-08-20 Sungene Gmbh & Co Kgaa PROCEDURE FOR THE OBTAINING OF FINE CHEMICALS BY CULTURE OF ORGANISMS THAT PRESENT A MODIFIED SHIQUIMATE ROUTE, NUCLEINIC ACID COMPOSITION, USE OF SUCH NUCLEINIC ACID FOR THE OBTAINING OF TRANSGENIC PLANTS, GENETICALLY PRODUCED PROCEDURE ORGANISM
US6326164B1 (en) * 2000-07-27 2001-12-04 Paradigm Genetics, Inc. Methods for determining deoxyxylulose 5-phosphate synthase activity
DE60140312D1 (en) * 2000-08-07 2009-12-10 Monsanto Technology Llc Am methyl-d-erythriol phosphat reaktionsweg beteiligte gene
DE10111676A1 (en) * 2001-03-09 2002-09-12 Sungene Gmbh & Co Kgaa Increasing vitamin E content in organisms by increasing tyrosine aminotransferase activity
CA2443865C (en) 2001-05-09 2012-02-07 Monsanto Technology Llc Tyra genes and uses thereof
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
AU2002329759A1 (en) 2001-08-17 2003-03-03 Monsanto Technology Llc Methyltransferase genes and uses thereof
US7262339B2 (en) 2001-10-25 2007-08-28 Monsanto Technology Llc Tocopherol methyltransferase tMT2 and uses thereof
EP1527180A4 (en) 2002-03-19 2006-02-15 Monsanto Technology Llc Homogentisate prenyl transferase ("hpt") nucleic acids and polypeptides, and uses thereof
WO2004013312A2 (en) 2002-08-05 2004-02-12 Monsanto Technology, Llc Tocopherol biosynthesis related genes and uses thereof
FR2844142B1 (en) 2002-09-11 2007-08-17 Bayer Cropscience Sa TRANSFORMED PLANTS WITH ENHANCED PRENYLQUINON BIOSYNTHESIS
DE10260871A1 (en) * 2002-12-23 2004-07-08 Sungene Gmbh & Co. Kgaa Process for the production of transgenic plants with increased vitamin E content by changing the serine acetyltransferase content
JP2007244240A (en) * 2006-03-14 2007-09-27 Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai Method for producing green callus cell

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19501906A1 (en) * 1995-01-23 1996-07-25 Basf Ag Transketolase
US6087563A (en) * 1996-01-29 2000-07-11 Arizona Board Of Regents On Behalf Of The University Of Arizona Cloned arabidopsis p-hydroxyphenyl pyruvic acid dioxygenase DNA
WO1998006862A1 (en) * 1996-08-09 1998-02-19 Calgene Llc Methods for producing carotenoid compounds and speciality oils in plant seeds
US6190895B1 (en) * 1997-09-02 2001-02-20 Washington State University Research Foundation Nucleic and amino acid sequences relating to a novel transketolase, and methods for the expression thereof
DE19752700A1 (en) * 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Deoxy-D-xylulose-5-phosphate synthase protein and modulators
CA2328157A1 (en) * 1998-04-14 1999-10-21 Jomaa Hassan Method for identifying chemical active agents and active agents for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthetic pathway

Also Published As

Publication number Publication date
AU757440B2 (en) 2003-02-20
CA2339519A1 (en) 2000-02-17
AU5415799A (en) 2000-02-28
WO2000008169A1 (en) 2000-02-17
JP2002525034A (en) 2002-08-13
EP1102852A1 (en) 2001-05-30

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