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WO2000026367A3 - Therapeutics and diagnostics for ocular abnormalities - Google Patents

Therapeutics and diagnostics for ocular abnormalities Download PDF

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Publication number
WO2000026367A3
WO2000026367A3 PCT/US1999/025440 US9925440W WO0026367A3 WO 2000026367 A3 WO2000026367 A3 WO 2000026367A3 US 9925440 W US9925440 W US 9925440W WO 0026367 A3 WO0026367 A3 WO 0026367A3
Authority
WO
WIPO (PCT)
Prior art keywords
therapeutics
diagnostics
ocular abnormalities
compositions
methods
Prior art date
Application number
PCT/US1999/025440
Other languages
French (fr)
Other versions
WO2000026367A2 (en
Inventor
Gregory S Hageman
Markus H Kuehn
Original Assignee
Univ Iowa Res Found
Gregory S Hageman
Markus H Kuehn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Iowa Res Found, Gregory S Hageman, Markus H Kuehn filed Critical Univ Iowa Res Found
Priority to AU17103/00A priority Critical patent/AU1710300A/en
Publication of WO2000026367A2 publication Critical patent/WO2000026367A2/en
Publication of WO2000026367A3 publication Critical patent/WO2000026367A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Methods and compositions for treating ocular disorders such as retinal detachment and macular degeneration and methods and compositions for prognosing or diagnosing retinal detachment or macular degeneration in a subject are disclosed.
PCT/US1999/025440 1998-10-29 1999-10-29 Therapeutics and diagnostics for ocular abnormalities WO2000026367A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU17103/00A AU1710300A (en) 1998-10-29 1999-10-29 Therapeutics and diagnostics for ocular abnormalities

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18397298A 1998-10-29 1998-10-29
US09/183,972 1998-10-29

Publications (2)

Publication Number Publication Date
WO2000026367A2 WO2000026367A2 (en) 2000-05-11
WO2000026367A3 true WO2000026367A3 (en) 2000-11-09

Family

ID=22675082

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/025440 WO2000026367A2 (en) 1998-10-29 1999-10-29 Therapeutics and diagnostics for ocular abnormalities

Country Status (2)

Country Link
AU (1) AU1710300A (en)
WO (1) WO2000026367A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9162024B2 (en) 2008-05-08 2015-10-20 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9180050B2 (en) 2004-08-17 2015-11-10 California Institute Of Technology Implantable intraocular pressure drain
US9199035B2 (en) 2008-05-08 2015-12-01 Minipumps, Llc. Drug-delivery pumps with dynamic, adaptive control
US9308124B2 (en) 2007-12-20 2016-04-12 University Of Southern California Apparatus and methods for delivering therapeutic agents

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7312050B2 (en) * 1998-10-29 2007-12-25 University Of Iowa Research Foundation Nucleic acids encoding interphotoreceptor matrix proteins
DE602007012417D1 (en) 2006-03-14 2011-03-24 Univ Southern California Mems device for drug release
ES2577502T3 (en) 2008-01-03 2016-07-15 University Of Southern California Implantable drug delivery devices and apparatus for recharging the devices
CN104758999B (en) 2008-05-08 2018-08-07 迷你泵有限责任公司 Implantable drug delivery devices and the device and method for filling the device
US9849238B2 (en) 2008-05-08 2017-12-26 Minipumps, Llc Drug-delivery pump with intelligent control
CN102202719B (en) 2008-05-08 2014-11-26 迷你泵有限责任公司 Implantable pumps and cannulas for implantable pumps
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK 24 February 1998 (1998-02-24), KUEHN M.H. & HAGEMAN G.S.: "H. sapiens interphotoreceptor matric porteoglycan 150 (IMPG1)", XP002137252 *
DATABASE GENBANK 24 February 1998 (1998-02-24), KUEHN M.H. ET AL.: "M. fascicularis interphotoreceptor matrix proteoglycan 150", XP002137251 *
GEHRIG A. ET AL.: "Assessment of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene localised to 6q13-q15 in autosomal dominant Stardgardt-like disease (ADSTGD), progressive bifocal chorioretinal atrophy (PBCRA) and North Carolina macular distrophy (MCDR1).", J. MED. GENETICS, vol. 35, no. 8, August 1998 (1998-08-01), pages 641 - 645, XP000906941 *
KUEHN M.H. & HAGEMAN G.S.: "Characterization of a cDNA encoding IPM150, a novel human interphotoreceptor matrix chondroitin 6-sulfate proteoglycan", INVEST. OPHTHALMOL. & VIS. SCI., vol. 36, no. 4, 15 March 1995 (1995-03-15), pages S510, XP000906940 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9180050B2 (en) 2004-08-17 2015-11-10 California Institute Of Technology Implantable intraocular pressure drain
US9308124B2 (en) 2007-12-20 2016-04-12 University Of Southern California Apparatus and methods for delivering therapeutic agents
US9162024B2 (en) 2008-05-08 2015-10-20 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9199035B2 (en) 2008-05-08 2015-12-01 Minipumps, Llc. Drug-delivery pumps with dynamic, adaptive control

Also Published As

Publication number Publication date
AU1710300A (en) 2000-05-22
WO2000026367A2 (en) 2000-05-11

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