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WO2001068840A3 - REGULATION DE LA PROTEINE HUMAINE SEMBLABLE A ACYLE CoA/INHIBITEUR DE LIAISON DU DIAZEPAM - Google Patents

REGULATION DE LA PROTEINE HUMAINE SEMBLABLE A ACYLE CoA/INHIBITEUR DE LIAISON DU DIAZEPAM Download PDF

Info

Publication number
WO2001068840A3
WO2001068840A3 PCT/EP2001/002780 EP0102780W WO0168840A3 WO 2001068840 A3 WO2001068840 A3 WO 2001068840A3 EP 0102780 W EP0102780 W EP 0102780W WO 0168840 A3 WO0168840 A3 WO 0168840A3
Authority
WO
WIPO (PCT)
Prior art keywords
regulation
protein
coa
acyl
binding inhibitor
Prior art date
Application number
PCT/EP2001/002780
Other languages
English (en)
Other versions
WO2001068840A2 (fr
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Shyam Ramakrishnan filed Critical Bayer Ag
Priority to AU2001250379A priority Critical patent/AU2001250379A1/en
Publication of WO2001068840A2 publication Critical patent/WO2001068840A2/fr
Publication of WO2001068840A3 publication Critical patent/WO2001068840A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

On peut utiliser des réactifs régulant l'activité de liaison de la protéine humaine semblable à DBI/ACBP et des réactifs se liant à des produits génétiques de protéine semblable à DBI/ACBP afin de réguler la prolifération cellulaire. Cette régulation est particulièrement utile pour traiter des cellules malignes, des maladies neurologiques et s'applique également à la biosynthèse des stéroïdes.
PCT/EP2001/002780 2000-03-14 2001-03-13 REGULATION DE LA PROTEINE HUMAINE SEMBLABLE A ACYLE CoA/INHIBITEUR DE LIAISON DU DIAZEPAM WO2001068840A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001250379A AU2001250379A1 (en) 2000-03-14 2001-04-13 Regulation of human diazepam binding inhibitor/acyl-coa-like protein

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18903800P 2000-03-14 2000-03-14
US60/189,038 2000-03-14
US25139300P 2000-12-06 2000-12-06
US60/251,393 2000-12-06

Publications (2)

Publication Number Publication Date
WO2001068840A2 WO2001068840A2 (fr) 2001-09-20
WO2001068840A3 true WO2001068840A3 (fr) 2002-03-07

Family

ID=26884722

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/002780 WO2001068840A2 (fr) 2000-03-14 2001-03-13 REGULATION DE LA PROTEINE HUMAINE SEMBLABLE A ACYLE CoA/INHIBITEUR DE LIAISON DU DIAZEPAM

Country Status (2)

Country Link
AU (1) AU2001250379A1 (fr)
WO (1) WO2001068840A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220096574A1 (en) * 2019-01-29 2022-03-31 Holobiome, Inc. Methods and compositions for treating and preventing central nervous system disorders and other conditions caused by gut microbial dysbiosis
WO2025134073A2 (fr) * 2023-12-22 2025-06-26 Institut National de la Santé et de la Recherche Médicale Méthodes et compositions pour le traitement de maladies ou d'affections induites par les corticostéroïdes, d'une inflammation synoviale et d'une maladie articulaire dégénérative
CN118141894A (zh) * 2024-02-04 2024-06-07 河北医科大学 Dbi及其水解产物肽在制备缓解外周神经疼痛药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006847A1 (fr) * 1996-08-16 1998-02-19 Incyte Pharmaceuticals, Inc. Proteine semblable a la dbi/acbp humaine
WO2001025436A2 (fr) * 1999-10-05 2001-04-12 Curagen Corporation Polypeptides de type endozepine et polynucleotides codant ces derniers

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006847A1 (fr) * 1996-08-16 1998-02-19 Incyte Pharmaceuticals, Inc. Proteine semblable a la dbi/acbp humaine
WO2001025436A2 (fr) * 1999-10-05 2001-04-12 Curagen Corporation Polypeptides de type endozepine et polynucleotides codant ces derniers

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_HUM EMBL Heidelberg, Germany; 6 November 1999 (1999-11-06), ROWEN L ET AL.: "Sequencing of human chromosome 15 D15S146-D15S117 region", XP002182180 *
LIHRMANN I ET AL: "Frog diazepam-binding inhibitor: Peptide sequence, cDNA cloning, and expression in the brain.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 91, no. 15, 1994, 1994, pages 6899 - 6903, XP002182179, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2001068840A2 (fr) 2001-09-20
AU2001250379A1 (en) 2001-09-24

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