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WO2002006309A3 - Peptides signaux d'exportation nucleaire (nes), proteines de fusion qui les contiennent, ainsi que leur utilisation - Google Patents

Peptides signaux d'exportation nucleaire (nes), proteines de fusion qui les contiennent, ainsi que leur utilisation Download PDF

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Publication number
WO2002006309A3
WO2002006309A3 PCT/EP2001/008065 EP0108065W WO0206309A3 WO 2002006309 A3 WO2002006309 A3 WO 2002006309A3 EP 0108065 W EP0108065 W EP 0108065W WO 0206309 A3 WO0206309 A3 WO 0206309A3
Authority
WO
WIPO (PCT)
Prior art keywords
signal peptides
same
fusion proteins
proteins containing
nes
Prior art date
Application number
PCT/EP2001/008065
Other languages
German (de)
English (en)
Other versions
WO2002006309A2 (fr
Inventor
Uwe Vinkemeier
Original Assignee
Forschungsverbund Berlin Ev
Uwe Vinkemeier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungsverbund Berlin Ev, Uwe Vinkemeier filed Critical Forschungsverbund Berlin Ev
Priority to AU2001276400A priority Critical patent/AU2001276400A1/en
Priority to EP01954035A priority patent/EP1301529A2/fr
Publication of WO2002006309A2 publication Critical patent/WO2002006309A2/fr
Publication of WO2002006309A3 publication Critical patent/WO2002006309A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des peptides signaux d'exportation nucléaire ainsi que des protéines de fusion qui les contiennent et que leur utilisation. Les peptides signaux de l'invention permettent de modifier le transport de structures biologiques entre le noyau et le cytoplasme.
PCT/EP2001/008065 2000-07-14 2001-07-12 Peptides signaux d'exportation nucleaire (nes), proteines de fusion qui les contiennent, ainsi que leur utilisation WO2002006309A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001276400A AU2001276400A1 (en) 2000-07-14 2001-07-12 Novel nucleus export signal peptides (nes), fusion proteins containing the same,and the use thereof
EP01954035A EP1301529A2 (fr) 2000-07-14 2001-07-12 Peptides signaux d'exportation nucleaire (nes), proteines de fusion qui les contiennent, ainsi que leur utilisation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2000135867 DE10035867A1 (de) 2000-07-14 2000-07-14 Neue Nucleus-Export-Signalpeptide (NES), sie enthaltende Fusionsproteine sowie deren Verwendung
DE10035867.5 2000-07-14

Publications (2)

Publication Number Publication Date
WO2002006309A2 WO2002006309A2 (fr) 2002-01-24
WO2002006309A3 true WO2002006309A3 (fr) 2002-05-23

Family

ID=7649945

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/008065 WO2002006309A2 (fr) 2000-07-14 2001-07-12 Peptides signaux d'exportation nucleaire (nes), proteines de fusion qui les contiennent, ainsi que leur utilisation

Country Status (4)

Country Link
EP (1) EP1301529A2 (fr)
AU (1) AU2001276400A1 (fr)
DE (1) DE10035867A1 (fr)
WO (1) WO2002006309A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117304282B (zh) * 2023-10-23 2025-02-18 安徽大学 一种核仁定位信号肽及其应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
OLAF ROSORIUS ET AL.: "Human Ribosomal Protein L5 Contains Defined Nuclear Localization and Export Signals", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 16, 21 April 2000 (2000-04-21), pages 12061 - 12068, XP002186817 *
TONY T. HUANG ET AL.: "A nuclear export signal in the N-terminal regulatory domain of I(kappa)B(alpha) controls cytoplasmic localization of inactive NF-(kappa)B/I(kappa)B(alpha) complexes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, vol. 97, no. 3, 1 February 2000 (2000-02-01), pages 1014 - 1019, XP002186818 *

Also Published As

Publication number Publication date
EP1301529A2 (fr) 2003-04-16
DE10035867A1 (de) 2002-01-31
WO2002006309A2 (fr) 2002-01-24
AU2001276400A1 (en) 2002-01-30

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