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WO2002010366A3 - Methods and compositions for diagnosing and treating chromosome-18p related disorders - Google Patents

Methods and compositions for diagnosing and treating chromosome-18p related disorders Download PDF

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Publication number
WO2002010366A3
WO2002010366A3 PCT/US2001/024417 US0124417W WO0210366A3 WO 2002010366 A3 WO2002010366 A3 WO 2002010366A3 US 0124417 W US0124417 W US 0124417W WO 0210366 A3 WO0210366 A3 WO 0210366A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
diagnosing
compositions
related disorders
disorder
Prior art date
Application number
PCT/US2001/024417
Other languages
French (fr)
Other versions
WO2002010366A2 (en
Inventor
Hong Chen
Nelson B Freimer
Thomas Novak
Original Assignee
Millennium Pharm Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Univ California filed Critical Millennium Pharm Inc
Priority to CA002417703A priority Critical patent/CA2417703A1/en
Priority to IL15423901A priority patent/IL154239A0/en
Priority to EP01959489A priority patent/EP1307549A2/en
Priority to AU2001281041A priority patent/AU2001281041A1/en
Publication of WO2002010366A2 publication Critical patent/WO2002010366A2/en
Publication of WO2002010366A3 publication Critical patent/WO2002010366A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to the mammalian HKNG1, GNKH and TS genes, genes associated with bipolar affective disorder (BAD) in humans. The invention relates, in particular, to methods for the diagnostic evaluation, genetic testing and prognosis of HKNG1, GNKH, and TS neuropsychiatric disorders including schizophrenia, attention deficit disorder, a schizoaffective disorder, a bipolar affective disorder or a unipolar affective disorder.
PCT/US2001/024417 2000-08-02 2001-08-02 Methods and compositions for diagnosing and treating chromosome-18p related disorders WO2002010366A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002417703A CA2417703A1 (en) 2000-08-02 2001-08-02 Methods and compositions for diagnosing and treating chromosome-18p related disorders
IL15423901A IL154239A0 (en) 2000-08-02 2001-08-02 Methods and compositions for diagnosing and treating chromosome-18p related disorders
EP01959489A EP1307549A2 (en) 2000-08-02 2001-08-02 Methods and compositions for diagnosing and treating chromosome-18p related disorders
AU2001281041A AU2001281041A1 (en) 2000-08-02 2001-08-02 Methods and compositions for diagnosing and treating chromosome-18p related disorders

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US63127500A 2000-08-02 2000-08-02
US09/631,275 2000-08-02
US72254400A 2000-11-28 2000-11-28
US09/722,544 2000-11-28

Publications (2)

Publication Number Publication Date
WO2002010366A2 WO2002010366A2 (en) 2002-02-07
WO2002010366A3 true WO2002010366A3 (en) 2002-08-29

Family

ID=27091342

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/024417 WO2002010366A2 (en) 2000-08-02 2001-08-02 Methods and compositions for diagnosing and treating chromosome-18p related disorders

Country Status (5)

Country Link
EP (1) EP1307549A2 (en)
AU (1) AU2001281041A1 (en)
CA (1) CA2417703A1 (en)
IL (1) IL154239A0 (en)
WO (1) WO2002010366A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114250224B (en) * 2021-12-16 2024-02-27 福建和瑞基因科技有限公司 Nucleic acid composition for extracting or detecting small-molecule RNA in sample, kit and method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999047535A1 (en) * 1998-03-16 1999-09-23 Millennium Pharmaceuticals, Inc. METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING CHROMOSOME-18p RELATED DISORDERS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999047535A1 (en) * 1998-03-16 1999-09-23 Millennium Pharmaceuticals, Inc. METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING CHROMOSOME-18p RELATED DISORDERS

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ROJAS K ET AL: "Identification of candidate genes for psychiatric disorders on 18p11.", MOLECULAR PSYCHIATRY, vol. 5, no. 4, July 2000 (2000-07-01), pages 389 - 395, XP001061966, ISSN: 1359-4184 *
YOSHIKAWA T ET AL: "ISOLATION OF CHROMOSOME 18-SPECIFIC BRAIN TRANSCRIPTS AS POSITIONALCANDIDATES FOR BIPOLAR DISORDER", AMERICAN JOURNAL OF MEDICAL GENETICS, NEW YORK,NY, US, vol. 74, no. 2, 18 April 1997 (1997-04-18), pages 140 - 149, XP001008133 *

Also Published As

Publication number Publication date
CA2417703A1 (en) 2002-02-07
IL154239A0 (en) 2003-07-31
EP1307549A2 (en) 2003-05-07
AU2001281041A1 (en) 2002-02-13
WO2002010366A2 (en) 2002-02-07

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