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WO2002010334A3 - Element d'adn promoteur de l'activite de transcription, actif dans les cellules humaines et methode generale pour en ajuster l'activite - Google Patents

Element d'adn promoteur de l'activite de transcription, actif dans les cellules humaines et methode generale pour en ajuster l'activite Download PDF

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Publication number
WO2002010334A3
WO2002010334A3 PCT/FR2001/002438 FR0102438W WO0210334A3 WO 2002010334 A3 WO2002010334 A3 WO 2002010334A3 FR 0102438 W FR0102438 W FR 0102438W WO 0210334 A3 WO0210334 A3 WO 0210334A3
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WO
WIPO (PCT)
Prior art keywords
activity
active
adjusting
general method
human cells
Prior art date
Application number
PCT/FR2001/002438
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English (en)
Other versions
WO2002010334A2 (fr
Inventor
Jean-Paul Issartel
Pierre Lescuyer
Original Assignee
Commissariat Energie Atomique
Centre Nat Rech Scient
Univ Joseph Fourier
Issartel Jean Paul
Pierre Lescuyer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique, Centre Nat Rech Scient, Univ Joseph Fourier, Issartel Jean Paul, Pierre Lescuyer filed Critical Commissariat Energie Atomique
Priority to EP01960836A priority Critical patent/EP1305403A2/fr
Publication of WO2002010334A2 publication Critical patent/WO2002010334A2/fr
Publication of WO2002010334A3 publication Critical patent/WO2002010334A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1247—DNA-directed RNA polymerase (2.7.7.6)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne un élément promoteur de l'activité de transcription de l'ARN polymérase caractérisé en ce qu'il comprend : i) les 241 nucléotides, s'étendant de la position 1630 à la position 1870, de la séquence illustrée dans la figure 1 ou ; ii) une partie de la séquence i) comprenant au moins l'un des trois motifs CCAAT représentés dans la figure 1 ou ; iii) une séquence ayant au moins 70 % d'identité avec la séquence i) ; le dit élément contenant au plus un site de fixation NRF1.
PCT/FR2001/002438 2000-07-28 2001-07-25 Element d'adn promoteur de l'activite de transcription, actif dans les cellules humaines et methode generale pour en ajuster l'activite WO2002010334A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP01960836A EP1305403A2 (fr) 2000-07-28 2001-07-25 Element d'adn promoteur de l'activite de transcription, actif dans les cellules humaines et methode generale pour en ajuster l'activite

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0010007A FR2812305B1 (fr) 2000-07-28 2000-07-28 Element d'adn promoteur de l'activite de transcription, actif dans les cellules humaines et methode generale pour en ajuster l'activite
FR00/10007 2000-07-28

Publications (2)

Publication Number Publication Date
WO2002010334A2 WO2002010334A2 (fr) 2002-02-07
WO2002010334A3 true WO2002010334A3 (fr) 2002-04-18

Family

ID=8853087

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2001/002438 WO2002010334A2 (fr) 2000-07-28 2001-07-25 Element d'adn promoteur de l'activite de transcription, actif dans les cellules humaines et methode generale pour en ajuster l'activite

Country Status (3)

Country Link
EP (1) EP1305403A2 (fr)
FR (1) FR2812305B1 (fr)
WO (1) WO2002010334A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995028490A1 (fr) * 1994-04-15 1995-10-26 Alliance Pharmaceutical Corp. Vecteur d'expression contenant un promoteur non viral
WO1999038972A2 (fr) * 1998-01-28 1999-08-05 Chiron Corporation Genes humains et produits ii d'expression genique

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995028490A1 (fr) * 1994-04-15 1995-10-26 Alliance Pharmaceutical Corp. Vecteur d'expression contenant un promoteur non viral
WO1999038972A2 (fr) * 1998-01-28 1999-08-05 Chiron Corporation Genes humains et produits ii d'expression genique

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ANGULO ANA ET AL: "Enhancer requirement for murine cytomegalovirus growth and genetic complementation by the human cytomegalovirus enhancer.", JOURNAL OF VIROLOGY, vol. 72, no. 11, November 1998 (1998-11-01), pages 8502 - 8509, XP002166751, ISSN: 0022-538X *
DATABASE EMBL [online] 15 June 1998 (1998-06-15), XP002166752, Database accession no. AC004923 *
DE SURY R ET AL: "Genomic structure of the human NDUFS8 gene coding for the iron-sulfur TYKY subunit of the mitochondrial NADH:ubiquinone oxidoreductase", GENE,NL,ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, vol. 215, no. 1, July 1998 (1998-07-01), pages 1 - 10, XP004149223, ISSN: 0378-1119 *
GRIMES SIDNEY R JR ET AL: "Regulation of transcription of the testis-specific histone H1t gene by multiple promoter elements.", MOLECULAR BIOLOGY REPORTS, vol. 24, no. 3, 1997, pages 175 - 184, XP001001402, ISSN: 0301-4851 *
HSU L C ET AL: "Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family", GENE,NL,ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, vol. 151, no. 1, 30 December 1994 (1994-12-30), pages 285 - 289, XP004042653, ISSN: 0378-1119 *
VANWERT JANE M ET AL: "The TE promoter element of the histone H1t gene is essential for transcription in transgenic mouse primary spermatocytes.", BIOLOGY OF REPRODUCTION, vol. 59, no. 3, 1998, pages 704 - 710, XP002166750, ISSN: 0006-3363 *

Also Published As

Publication number Publication date
WO2002010334A2 (fr) 2002-02-07
EP1305403A2 (fr) 2003-05-02
FR2812305A1 (fr) 2002-02-01
FR2812305B1 (fr) 2005-01-07

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