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WO2002019998A3 - A method of treating weight gain associated with atypical antipsychotic use - Google Patents

A method of treating weight gain associated with atypical antipsychotic use Download PDF

Info

Publication number
WO2002019998A3
WO2002019998A3 PCT/US2001/022621 US0122621W WO0219998A3 WO 2002019998 A3 WO2002019998 A3 WO 2002019998A3 US 0122621 W US0122621 W US 0122621W WO 0219998 A3 WO0219998 A3 WO 0219998A3
Authority
WO
WIPO (PCT)
Prior art keywords
weight gain
atypical antipsychotic
gain associated
treating weight
antipsychotic use
Prior art date
Application number
PCT/US2001/022621
Other languages
French (fr)
Other versions
WO2002019998A2 (en
Inventor
Alan Breier
Mark Louis Heiman
John David Leander
Original Assignee
Lilly Co Eli
Alan Breier
Mark Louis Heiman
John David Leander
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Alan Breier, Mark Louis Heiman, John David Leander filed Critical Lilly Co Eli
Priority to AU2001282913A priority Critical patent/AU2001282913A1/en
Publication of WO2002019998A2 publication Critical patent/WO2002019998A2/en
Publication of WO2002019998A3 publication Critical patent/WO2002019998A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A method of treating weight gain associated with atypical antipsychotic use which comprises administering to a mammal in need thereof a therapeutically effective amount of N,N-dimethyl-1-[1-(4-chlorophenyl) cyclobutyl]-3-methylbutylamine hydrochloride.
PCT/US2001/022621 2000-09-08 2001-08-24 A method of treating weight gain associated with atypical antipsychotic use WO2002019998A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001282913A AU2001282913A1 (en) 2000-09-08 2001-08-24 A method of treating weight gain associated with atypical antipsychotic use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23106500P 2000-09-08 2000-09-08
US60/231,065 2000-09-08

Publications (2)

Publication Number Publication Date
WO2002019998A2 WO2002019998A2 (en) 2002-03-14
WO2002019998A3 true WO2002019998A3 (en) 2003-01-23

Family

ID=22867618

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/022621 WO2002019998A2 (en) 2000-09-08 2001-08-24 A method of treating weight gain associated with atypical antipsychotic use

Country Status (2)

Country Link
AU (1) AU2001282913A1 (en)
WO (1) WO2002019998A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE486842T1 (en) 2002-03-12 2010-11-15 Merck Sharp & Dohme SUBSTITUTED AMIDES
DE60330864D1 (en) 2002-06-19 2010-02-25 Biovitrum Ab Publ NEW CONNECTIONS, THEIR USE AND MANUFACTURE
CA2622696A1 (en) * 2007-11-05 2009-05-05 Diane Mcintosh Methods and compositions for retarding weight gain associated with use of atypical antipsychotic drugs
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436272A (en) * 1988-11-29 1995-07-25 The Boots Company (Usa), Inc. Treatment of obesity
US5736541A (en) * 1995-03-24 1998-04-07 Eli Lilly And Company Olanzapine polymorph crystal form
WO2000056313A1 (en) * 1999-03-19 2000-09-28 Knoll Gmbh Method of controlling weight gain associated with therapeutic drugs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436272A (en) * 1988-11-29 1995-07-25 The Boots Company (Usa), Inc. Treatment of obesity
US5736541A (en) * 1995-03-24 1998-04-07 Eli Lilly And Company Olanzapine polymorph crystal form
WO2000056313A1 (en) * 1999-03-19 2000-09-28 Knoll Gmbh Method of controlling weight gain associated with therapeutic drugs

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ALLISON D.B. ET AL: "Antipsychotic -induced weight gain: A review of the literature.", JOURNAL OF CLINICAL PSYCHIATRY, (2001) 62/SUPPL. 7 (22-31)., XP008005159 *
BLACKBURN G.L. ET AL: "Weight gain and antipsychotic medication.", JOURNAL OF CLINICAL PSYCHIATRY, (2000) 61/SUPPL. 8 (36-42)., XP008005169 *
CASEY D.E. ET AL: "The pharmacology of weight gain with antipsychotics.", JOURNAL OF CLINICAL PSYCHIATRY, (2001) 62/SUPPL. 7 (4-10)., XP008005168 *
GREENBERG ISAAC ET AL: "Nonpharmacologic and pharmacologic management of weight gain.", JOURNAL OF CLINICAL PSYCHIATRY, vol. 60, no. SUPPL. 21, 1999, pages 31 - 36, XP008005348, ISSN: 0160-6689 *
KURZTHALER I. ET AL: "The clinical implications of weight gain in schizophrenia.", JOURNAL OF CLINICAL PSYCHIATRY, (2001) 62/SUPPL. 7 (32-37)., XP008005160 *

Also Published As

Publication number Publication date
WO2002019998A2 (en) 2002-03-14
AU2001282913A1 (en) 2002-03-22

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