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WO2002032924A3 - Haplotypes du gene chrm5 - Google Patents

Haplotypes du gene chrm5 Download PDF

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Publication number
WO2002032924A3
WO2002032924A3 PCT/US2001/032022 US0132022W WO0232924A3 WO 2002032924 A3 WO2002032924 A3 WO 2002032924A3 US 0132022 W US0132022 W US 0132022W WO 0232924 A3 WO0232924 A3 WO 0232924A3
Authority
WO
WIPO (PCT)
Prior art keywords
chrm5
gene
haplotypes
disclosed
haplotyping
Prior art date
Application number
PCT/US2001/032022
Other languages
English (en)
Other versions
WO2002032924A2 (fr
Inventor
Karyn M Bieglecki
Anne Chew
Julie Y Choi
R Rex Denton
Krishnan Nandabalan
Elizabeth Ann Sausker
J Claiborne Stephens
Original Assignee
Genaissance Pharmaceuticals
Karyn M Bieglecki
Anne Chew
Julie Y Choi
R Rex Denton
Krishnan Nandabalan
Elizabeth Ann Sausker
J Claiborne Stephens
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2000/029071 external-priority patent/WO2001028995A2/fr
Application filed by Genaissance Pharmaceuticals, Karyn M Bieglecki, Anne Chew, Julie Y Choi, R Rex Denton, Krishnan Nandabalan, Elizabeth Ann Sausker, J Claiborne Stephens filed Critical Genaissance Pharmaceuticals
Priority to AU2002213185A priority Critical patent/AU2002213185A1/en
Publication of WO2002032924A2 publication Critical patent/WO2002032924A2/fr
Publication of WO2002032924A3 publication Critical patent/WO2002032924A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La présente invention concerne des nouveaux variants génétiques du gène muscarinique 5 du récepteur cholinergique (gène CHRM5). L'invention concerne également divers génotypes, haplotypes, et paires d'haplotypes existant dans la population générale des Etats-Unis pour le gène CHRM5. En outre, l'invention concerne des compositions et des méthodes d'haplotypage et/ou de génotypage du gène CHRM5 chez un individu. L'invention concerne également des polynucléotides définis par les haplotypes de l'invention.
PCT/US2001/032022 2000-10-19 2001-10-11 Haplotypes du gene chrm5 WO2002032924A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002213185A AU2002213185A1 (en) 2000-10-19 2001-10-11 Haplotypes of the chrm5 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
USPCT/US00/29071 2000-10-19
PCT/US2000/029071 WO2001028995A2 (fr) 1999-10-21 2000-10-19 Isogenes cibles de medicament: polymorphismes dans le gene muscarinique 5 recepteur cholinergique

Publications (2)

Publication Number Publication Date
WO2002032924A2 WO2002032924A2 (fr) 2002-04-25
WO2002032924A3 true WO2002032924A3 (fr) 2002-08-01

Family

ID=21741914

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/032022 WO2002032924A2 (fr) 2000-10-19 2001-10-11 Haplotypes du gene chrm5

Country Status (2)

Country Link
AU (1) AU2002213185A1 (fr)
WO (1) WO2002032924A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1306037C (zh) * 2004-10-19 2007-03-21 哈尔滨医科大学 心肌细胞m3受体及ikm3作为筛选治疗心律失常药物的用途

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BONNER ET AL.: "Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes", NEURON, vol. 1, no. 5, July 1988 (1988-07-01), pages 403 - 410, XP002916494 *
BROOKES ET AL.: "HGBASE: a database of SNPs and other variations in and around human genes", NUCLEIC ACIDS RESEARCH, vol. 28, no. 1, 2000, pages 356 - 360, XP002946185 *
MCCARTHY ET AL.: "The use of single-nucleotide polymorphism maps in pharmacogenomics", NATURE BIOTECHNOLOGY, vol. 18, May 2000 (2000-05-01), pages 505 - 508, XP000941628 *
STEPHENS: "Single-nucleotide polymorphisms, haplotypes and their relevance to pharmacogenetics", MOLECULAR DIAGNOSTICS, vol. 4, no. 4, 1999, pages 309 - 317, XP002937520 *

Also Published As

Publication number Publication date
WO2002032924A2 (fr) 2002-04-25
AU2002213185A1 (en) 2002-04-29

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