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WO2003048320A3 - Nouvelle proteine moteur de p. falciparum et methodes d'utilisation de cette derniere - Google Patents

Nouvelle proteine moteur de p. falciparum et methodes d'utilisation de cette derniere Download PDF

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Publication number
WO2003048320A3
WO2003048320A3 PCT/US2002/038360 US0238360W WO03048320A3 WO 2003048320 A3 WO2003048320 A3 WO 2003048320A3 US 0238360 W US0238360 W US 0238360W WO 03048320 A3 WO03048320 A3 WO 03048320A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
pfkini
falciparum
novel motor
motor protein
Prior art date
Application number
PCT/US2002/038360
Other languages
English (en)
Other versions
WO2003048320A2 (fr
Inventor
Roman Sakowicz
Christophe Beraud
Jun Guo
Richard Freedman
Original Assignee
Cytokinetics Inc
Roman Sakowicz
Christophe Beraud
Jun Guo
Richard Freedman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/006,780 external-priority patent/US20030104496A1/en
Application filed by Cytokinetics Inc, Roman Sakowicz, Christophe Beraud, Jun Guo, Richard Freedman filed Critical Cytokinetics Inc
Priority to EP02786833A priority Critical patent/EP1528932A4/fr
Priority to AU2002351186A priority patent/AU2002351186A1/en
Publication of WO2003048320A2 publication Critical patent/WO2003048320A2/fr
Publication of WO2003048320A3 publication Critical patent/WO2003048320A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des séquences isolées d'acides nucléiques et d'acides aminés de PfKinI-1, des anticorps dirigés contre PfKinI-1, des méthodes de criblage de modulateurs PfKinI-1 dans lesquelles on utilise des PfKinI-1 biologiquement actives et des trousses permettant de cribler des modulateurs PfKinI-1.
PCT/US2002/038360 2001-11-30 2002-11-27 Nouvelle proteine moteur de p. falciparum et methodes d'utilisation de cette derniere WO2003048320A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02786833A EP1528932A4 (fr) 2001-11-30 2002-11-27 Nouvelle proteine moteur de p. falciparum et methodes d'utilisation de cette derniere
AU2002351186A AU2002351186A1 (en) 2001-11-30 2002-11-27 Novel motor protein of p. falciparum and methods for its use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/006,780 US20030104496A1 (en) 2001-11-30 2001-11-30 Novel motor protein of P. falciparum and methods for its use
US10/006,780 2001-11-30
US8693502A 2002-02-28 2002-02-28
US10/086,935 2002-02-28

Publications (2)

Publication Number Publication Date
WO2003048320A2 WO2003048320A2 (fr) 2003-06-12
WO2003048320A3 true WO2003048320A3 (fr) 2005-03-17

Family

ID=33566918

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/038360 WO2003048320A2 (fr) 2001-11-30 2002-11-27 Nouvelle proteine moteur de p. falciparum et methodes d'utilisation de cette derniere

Country Status (3)

Country Link
EP (1) EP1528932A4 (fr)
AU (1) AU2002351186A1 (fr)
WO (1) WO2003048320A2 (fr)

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BEJON P.A.: "A role for microtubules in plasmodium falciparum merozoite invasion", PARASITOLOGY, vol. 114, 1997, pages 1 - 6, XP002971549 *
FOWLER R.E.: "Microtubules in plasmodium falciparum merozoites and their importance for invasion of erythrocytes", PARASITOLOGY, vol. 117, 1998, pages 425 - 433, XP002971550 *
GOLDSTEIN L.S.B.: "With apologies to scheherazade: tails of 1001 kinesin motors", ANNU. REV,. GENET., vol. 27, 1993, pages 319 - 351, XP002971551 *
KIM I.G.: "Cloning and expression of human mitotic centromere-associated kinesin gene", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1359, 1997, pages 181 - 186, XP004277796 *
See also references of EP1528932A4 *

Also Published As

Publication number Publication date
AU2002351186A1 (en) 2003-06-17
AU2002351186A8 (en) 2003-06-17
EP1528932A4 (fr) 2005-11-09
WO2003048320A2 (fr) 2003-06-12
EP1528932A2 (fr) 2005-05-11

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