WO2003008012A2 - Procede et dispositif de preparation du sang - Google Patents
Procede et dispositif de preparation du sang Download PDFInfo
- Publication number
- WO2003008012A2 WO2003008012A2 PCT/EP2002/007855 EP0207855W WO03008012A2 WO 2003008012 A2 WO2003008012 A2 WO 2003008012A2 EP 0207855 W EP0207855 W EP 0207855W WO 03008012 A2 WO03008012 A2 WO 03008012A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- chambers
- preparation
- chamber
- preparation device
- sample
- Prior art date
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 60
- 239000008280 blood Substances 0.000 title claims abstract description 60
- 238000000034 method Methods 0.000 title claims description 23
- 238000002360 preparation method Methods 0.000 claims abstract description 114
- 239000000725 suspension Substances 0.000 claims abstract description 18
- 239000000654 additive Substances 0.000 claims abstract description 7
- 238000005119 centrifugation Methods 0.000 claims description 25
- 238000007789 sealing Methods 0.000 claims description 15
- 230000005540 biological transmission Effects 0.000 claims description 11
- 238000011068 loading method Methods 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 238000007639 printing Methods 0.000 claims description 5
- 239000012780 transparent material Substances 0.000 claims description 2
- 238000012546 transfer Methods 0.000 abstract description 11
- 210000003743 erythrocyte Anatomy 0.000 description 16
- 239000000523 sample Substances 0.000 description 16
- 230000008901 benefit Effects 0.000 description 14
- 238000013461 design Methods 0.000 description 11
- 229920003023 plastic Polymers 0.000 description 8
- 239000013049 sediment Substances 0.000 description 8
- 239000006228 supernatant Substances 0.000 description 8
- 239000007788 liquid Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 239000004033 plastic Substances 0.000 description 6
- 238000005138 cryopreservation Methods 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 238000010276 construction Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- 238000001514 detection method Methods 0.000 description 3
- 238000007710 freezing Methods 0.000 description 3
- 230000008014 freezing Effects 0.000 description 3
- 230000036512 infertility Effects 0.000 description 3
- 239000004810 polytetrafluoroethylene Substances 0.000 description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 3
- 210000000130 stem cell Anatomy 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 238000009924 canning Methods 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000002706 hydrostatic effect Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 235000013324 preserved food Nutrition 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- MCSXGCZMEPXKIW-UHFFFAOYSA-N 3-hydroxy-4-[(4-methyl-2-nitrophenyl)diazenyl]-N-(3-nitrophenyl)naphthalene-2-carboxamide Chemical compound Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C(=O)Nc2cccc(c2)[N+]([O-])=O)c(c1)[N+]([O-])=O MCSXGCZMEPXKIW-UHFFFAOYSA-N 0.000 description 1
- RZGZMLICFFEUIQ-UHFFFAOYSA-N 5-[(1-phenylcyclohexyl)amino]pentanoic acid Chemical compound C=1C=CC=CC=1C1(NCCCCC(=O)O)CCCCC1 RZGZMLICFFEUIQ-UHFFFAOYSA-N 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 210000003850 cellular structure Anatomy 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000002510 pyrogen Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000010023 transfer printing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/029—Separating blood components present in distinct layers in a container, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
Definitions
- FIG. 5 shows a schematic sectional view of a single chamber used according to the invention
- valve plate 21 is shown individually.
- two connecting lines (or overflow channels) 22, 23 are provided, which are arranged such that two chambers can be connected to one of the connecting lines 22 or 23, while the other connecting line 22 or 23 is closed.
- the use of two connecting lines has the advantage of shorter adjustment paths when setting the chamber connections in the individual preparation steps.
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Centrifugal Separators (AREA)
- Sampling And Sample Adjustment (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002331254A AU2002331254A1 (en) | 2001-07-18 | 2002-07-15 | Device and method for preparing blood |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10134913.0 | 2001-07-18 | ||
DE10134913A DE10134913C2 (de) | 2001-07-18 | 2001-07-18 | Vorrichtung und Verfahren zur Blutpräparation |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2003008012A2 true WO2003008012A2 (fr) | 2003-01-30 |
WO2003008012A3 WO2003008012A3 (fr) | 2003-04-03 |
WO2003008012A8 WO2003008012A8 (fr) | 2004-06-10 |
Family
ID=7692196
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2002/007855 WO2003008012A2 (fr) | 2001-07-18 | 2002-07-15 | Procede et dispositif de preparation du sang |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2002331254A1 (fr) |
DE (1) | DE10134913C2 (fr) |
WO (1) | WO2003008012A2 (fr) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3028771A1 (fr) * | 2014-11-24 | 2016-05-27 | Inst Nat De La Rech Agronomique (Inra) | Dispositif d'extraction de liquide depuis une substance, notamment depuis des graines oleagineuses |
US10596315B2 (en) | 2012-10-11 | 2020-03-24 | Magnolia Medical Technologies, Inc. | Systems and methods for delivering a fluid to a patient with reduced contamination |
US10624977B2 (en) | 2015-09-03 | 2020-04-21 | Magnolia Medical Technologies, Inc. | Apparatus and methods for maintaining sterility of a specimen container |
CN111498355A (zh) * | 2019-01-31 | 2020-08-07 | 青岛海尔生物医疗股份有限公司 | 转盘式自动化血液存储装置及存取方法 |
US10736554B2 (en) | 2012-05-30 | 2020-08-11 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US10772548B2 (en) | 2012-12-04 | 2020-09-15 | Magnolia Medical Technologies, Inc. | Sterile bodily-fluid collection device and methods |
US10881343B2 (en) | 2012-08-01 | 2021-01-05 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US11076787B2 (en) | 2017-09-12 | 2021-08-03 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
US11234626B2 (en) | 2015-06-12 | 2022-02-01 | Magnolia Medical Technologies, Inc. | Devices and methods for syringe-based fluid transfer for bodily-fluid sampling |
US11259727B2 (en) | 2012-12-04 | 2022-03-01 | Magnolia Medical Technologies, Inc. | Sterile bodily-fluid collection device and methods |
US11311218B2 (en) | 2012-11-30 | 2022-04-26 | Magnolia Medical Technologies, Inc. | Syringe-based fluid diversion mechanism for bodily fluid sampling |
US11395611B2 (en) | 2012-05-30 | 2022-07-26 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US11419531B2 (en) | 2017-12-07 | 2022-08-23 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
US11786155B2 (en) | 2019-02-08 | 2023-10-17 | Magnolia Medical Technologies, Inc. | Devices and methods for bodily fluid collection and distribution |
US11857321B2 (en) | 2019-03-11 | 2024-01-02 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2969987T3 (es) * | 2006-06-20 | 2024-05-23 | Erik John Woods | Dispositivo de criopreservación |
US8709797B2 (en) | 2006-06-20 | 2014-04-29 | Cook General Biotechnology Llc | Systems and methods for cryopreservation of cells |
US9820682B2 (en) | 2015-07-24 | 2017-11-21 | Kurin, Inc. | Blood sample optimization system and blood contaminant sequestration device and method |
US10827964B2 (en) | 2017-02-10 | 2020-11-10 | Kurin, Inc. | Blood contaminant sequestration device with one-way air valve and air-permeable blood barrier with closure mechanism |
CN112771362B (zh) | 2019-04-01 | 2024-11-26 | 酷睿有限公司 | 非排气机体流体样品优化装置和系统 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE29805538U1 (de) | 1998-03-26 | 1998-06-04 | Gebauer GmbH Gerätebau-Elektronik, 75242 Neuhausen | Blutbeutel-Handler |
WO2000038762A1 (fr) | 1998-12-24 | 2000-07-06 | Biosafe S.A. | Systeme de separation sanguine convenant en particulier pour la concentration de cellules souche hematopoietiques |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3185154A (en) * | 1962-08-14 | 1965-05-25 | Joseph F Caccavo | Apparatus for collecting, separating, storing and dispensing whole blood |
EP0335882A4 (en) * | 1986-10-31 | 1990-09-26 | North American Biologicals, Inc. | Improved cryoglobulin separation |
JPH039754A (ja) * | 1989-06-07 | 1991-01-17 | Daihachi Matsuura | 密閉混合容器 |
US5674394A (en) * | 1995-03-24 | 1997-10-07 | Johnson & Johnson Medical, Inc. | Single use system for preparation of autologous plasma |
AU721671B2 (en) * | 1997-01-08 | 2000-07-13 | Vivolution A/S | Centrifuge apparatus for separating blood |
-
2001
- 2001-07-18 DE DE10134913A patent/DE10134913C2/de not_active Expired - Fee Related
-
2002
- 2002-07-15 WO PCT/EP2002/007855 patent/WO2003008012A2/fr not_active Application Discontinuation
- 2002-07-15 AU AU2002331254A patent/AU2002331254A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE29805538U1 (de) | 1998-03-26 | 1998-06-04 | Gebauer GmbH Gerätebau-Elektronik, 75242 Neuhausen | Blutbeutel-Handler |
WO2000038762A1 (fr) | 1998-12-24 | 2000-07-06 | Biosafe S.A. | Systeme de separation sanguine convenant en particulier pour la concentration de cellules souche hematopoietiques |
Cited By (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11395611B2 (en) | 2012-05-30 | 2022-07-26 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US11998332B2 (en) | 2012-05-30 | 2024-06-04 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US11819329B2 (en) | 2012-05-30 | 2023-11-21 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US12193816B2 (en) | 2012-05-30 | 2025-01-14 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US10736554B2 (en) | 2012-05-30 | 2020-08-11 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US10912506B2 (en) | 2012-05-30 | 2021-02-09 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US12186080B2 (en) | 2012-05-30 | 2025-01-07 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US11395612B2 (en) | 2012-05-30 | 2022-07-26 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US10881343B2 (en) | 2012-08-01 | 2021-01-05 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
US10596315B2 (en) | 2012-10-11 | 2020-03-24 | Magnolia Medical Technologies, Inc. | Systems and methods for delivering a fluid to a patient with reduced contamination |
US12133968B2 (en) | 2012-10-11 | 2024-11-05 | Magnolia Medical Technologies, Inc. | Systems and methods for delivering a fluid to a patient with reduced contamination |
US11890452B2 (en) | 2012-10-11 | 2024-02-06 | Magnolia Medical Technologies, Inc. | Systems and methods for delivering a fluid to a patient with reduced contamination |
US11589786B2 (en) | 2012-11-30 | 2023-02-28 | Magnolia Medical Technologies, Inc. | Syringe-based fluid diversion mechanism for bodily fluid sampling |
US11607159B2 (en) | 2012-11-30 | 2023-03-21 | Magnolia Medical Technologies, Inc. | Bodily-fluid transfer system for bodily fluid sampling |
US11311218B2 (en) | 2012-11-30 | 2022-04-26 | Magnolia Medical Technologies, Inc. | Syringe-based fluid diversion mechanism for bodily fluid sampling |
US11317838B2 (en) | 2012-11-30 | 2022-05-03 | Magnolia Medical Technologies, Inc. | Syringe-based fluid diversion mechanism for bodily fluid sampling |
US11660030B2 (en) | 2012-11-30 | 2023-05-30 | Magnolia Medical Technologies, Inc. | Syringe-based fluid diversion mechanism for bodily fluid sampling |
US11737693B2 (en) | 2012-12-04 | 2023-08-29 | Magnolia Medical Technologies, Inc. | Sterile bodily-fluid collection device and methods |
US12150763B2 (en) | 2012-12-04 | 2024-11-26 | Magnolia Medical Technologies, Inc. | Sterile bodily-fluid collection device and methods |
US10772548B2 (en) | 2012-12-04 | 2020-09-15 | Magnolia Medical Technologies, Inc. | Sterile bodily-fluid collection device and methods |
US11259727B2 (en) | 2012-12-04 | 2022-03-01 | Magnolia Medical Technologies, Inc. | Sterile bodily-fluid collection device and methods |
FR3028771A1 (fr) * | 2014-11-24 | 2016-05-27 | Inst Nat De La Rech Agronomique (Inra) | Dispositif d'extraction de liquide depuis une substance, notamment depuis des graines oleagineuses |
WO2016083349A1 (fr) * | 2014-11-24 | 2016-06-02 | Institut National De La Recherche Agronomique (Inra) | Dispositif d'extraction de liquide depuis une substance, notamment depuis des graines oléagineuses |
US11234626B2 (en) | 2015-06-12 | 2022-02-01 | Magnolia Medical Technologies, Inc. | Devices and methods for syringe-based fluid transfer for bodily-fluid sampling |
US12083234B2 (en) | 2015-09-03 | 2024-09-10 | Magnolia Medical Technologies, Inc. | Apparatus and methods for maintaining sterility of a specimen container |
US10624977B2 (en) | 2015-09-03 | 2020-04-21 | Magnolia Medical Technologies, Inc. | Apparatus and methods for maintaining sterility of a specimen container |
US11076787B2 (en) | 2017-09-12 | 2021-08-03 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
US11903710B2 (en) | 2017-09-12 | 2024-02-20 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
US11903709B2 (en) | 2017-09-12 | 2024-02-20 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
US11653863B2 (en) | 2017-09-12 | 2023-05-23 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
US11529081B2 (en) | 2017-09-12 | 2022-12-20 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
US12290363B2 (en) | 2017-09-12 | 2025-05-06 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
US11419531B2 (en) | 2017-12-07 | 2022-08-23 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
CN111498355A (zh) * | 2019-01-31 | 2020-08-07 | 青岛海尔生物医疗股份有限公司 | 转盘式自动化血液存储装置及存取方法 |
US11786155B2 (en) | 2019-02-08 | 2023-10-17 | Magnolia Medical Technologies, Inc. | Devices and methods for bodily fluid collection and distribution |
US11857321B2 (en) | 2019-03-11 | 2024-01-02 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
Also Published As
Publication number | Publication date |
---|---|
DE10134913A1 (de) | 2003-02-20 |
WO2003008012A8 (fr) | 2004-06-10 |
WO2003008012A3 (fr) | 2003-04-03 |
DE10134913C2 (de) | 2003-06-26 |
AU2002331254A1 (en) | 2003-03-03 |
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