[go: up one dir, main page]

WO2003010561A3 - Coupleur optique destine a mesurer la fluorescence des tissus - Google Patents

Coupleur optique destine a mesurer la fluorescence des tissus Download PDF

Info

Publication number
WO2003010561A3
WO2003010561A3 PCT/US2002/023412 US0223412W WO03010561A3 WO 2003010561 A3 WO2003010561 A3 WO 2003010561A3 US 0223412 W US0223412 W US 0223412W WO 03010561 A3 WO03010561 A3 WO 03010561A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
coupler
optical coupler
spectroscope
light
Prior art date
Application number
PCT/US2002/023412
Other languages
English (en)
Other versions
WO2003010561A2 (fr
Inventor
Robert G Messerschmidt
Jim Childs
Pierre Trepagnier
James Mansfield
Jenny E Freeman
Sean Toy
Britton Chance
Original Assignee
Argose Inc
Robert G Messerschmidt
Jim Childs
Pierre Trepagnier
James Mansfield
Jenny E Freeman
Sean Toy
Britton Chance
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Argose Inc, Robert G Messerschmidt, Jim Childs, Pierre Trepagnier, James Mansfield, Jenny E Freeman, Sean Toy, Britton Chance filed Critical Argose Inc
Priority to AU2002322606A priority Critical patent/AU2002322606A1/en
Publication of WO2003010561A2 publication Critical patent/WO2003010561A2/fr
Publication of WO2003010561A3 publication Critical patent/WO2003010561A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6834—Means for maintaining contact with the body using vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/14—Coupling media or elements to improve sensor contact with skin or tissue
    • A61B2562/146—Coupling media or elements to improve sensor contact with skin or tissue for optical coupling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

L'invention concerne un dispositif destiné à coupler optiquement de manière efficace des tissus à un spectroscope. Le coupleur optique comprend, de préférence, une enveloppe partielle et rigide comportant une paroi intérieure qui réfléchit le rayonnement électromagnétique, une ouverture sur l'enveloppe destinée au passage de la lumière et un ou plusieurs miroirs, ainsi que des paires de détecteurs de lumière. Le coupleur peut consister en un composant d'un système spectroscopique de tissu comprenant un ou plusieurs coupleurs, un spectroscope, et un milieu d'interface, un détecteur ainsi qu'une source de lumière. Le procédé de l'invention permet la détection de propriétés optiques d'un tissu et, de préférence, de la peau.
PCT/US2002/023412 2001-07-25 2002-07-24 Coupleur optique destine a mesurer la fluorescence des tissus WO2003010561A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002322606A AU2002322606A1 (en) 2001-07-25 2002-07-24 Optical coupler for measuring tissue fluorescence

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30736801P 2001-07-25 2001-07-25
US60/307,368 2001-07-25

Publications (2)

Publication Number Publication Date
WO2003010561A2 WO2003010561A2 (fr) 2003-02-06
WO2003010561A3 true WO2003010561A3 (fr) 2003-06-19

Family

ID=23189445

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/023412 WO2003010561A2 (fr) 2001-07-25 2002-07-24 Coupleur optique destine a mesurer la fluorescence des tissus

Country Status (2)

Country Link
AU (1) AU2002322606A1 (fr)
WO (1) WO2003010561A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011150919A2 (fr) * 2010-06-01 2011-12-08 Mfd Diagnostics Gmbh Sonde optique pourvue d'une tête de sonde et d'une virole de sonde
FI123363B (fi) 2011-01-31 2013-03-15 Clothing Plus Holding Oy Tekstiilinen alusta fysikaalisen suureen mittaamiseksi
EP3028587B1 (fr) 2014-12-03 2020-03-11 Clothing Plus MBU Oy Dispositif permettant de déterminer les effets du vieillissement d'un dispositif portable
CN116297278B (zh) * 2023-02-23 2025-05-06 广西电网有限责任公司电力科学研究院 一种六氟化硫分解组分检测装置及方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622974A (en) * 1984-03-07 1986-11-18 University Of Tennessee Research Corporation Apparatus and method for in-vivo measurements of chemical concentrations
US4681442A (en) * 1984-05-14 1987-07-21 International Business Machines Corporation Method for surface testing
US5741213A (en) * 1995-10-25 1998-04-21 Toa Medical Electronics Co., Ltd. Apparatus for analyzing blood
US5846513A (en) * 1997-07-08 1998-12-08 Carewise Medical Products Corporation Tumor localization and removal system using penetratable detection probe and removal instrument
US6167290A (en) * 1999-02-03 2000-12-26 Bayspec, Inc. Method and apparatus of non-invasive measurement of human/animal blood glucose and other metabolites

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622974A (en) * 1984-03-07 1986-11-18 University Of Tennessee Research Corporation Apparatus and method for in-vivo measurements of chemical concentrations
US4681442A (en) * 1984-05-14 1987-07-21 International Business Machines Corporation Method for surface testing
US5741213A (en) * 1995-10-25 1998-04-21 Toa Medical Electronics Co., Ltd. Apparatus for analyzing blood
US5846513A (en) * 1997-07-08 1998-12-08 Carewise Medical Products Corporation Tumor localization and removal system using penetratable detection probe and removal instrument
US5846513B1 (en) * 1997-07-08 2000-11-28 Carewise Medical Products Corp Tumor localization and removal system using penetratable detection probe and removal instrument
US6167290A (en) * 1999-02-03 2000-12-26 Bayspec, Inc. Method and apparatus of non-invasive measurement of human/animal blood glucose and other metabolites

Also Published As

Publication number Publication date
AU2002322606A1 (en) 2003-02-17
WO2003010561A2 (fr) 2003-02-06

Similar Documents

Publication Publication Date Title
JP4459208B2 (ja) 光センサを具備する内視鏡光源安全制御システム
WO2007041591A3 (fr) Detection de plaque vulnerable
US20070280612A1 (en) Method and apparatus for fiberscope
US5608520A (en) Plasma emission spectroscopy method of tumor therapy
JP4597114B2 (ja) 内視鏡に関する安全システム、および、内視鏡に関する安全システムにおける内視鏡の存在を検出するための光学的センサ
WO2006045013A3 (fr) Diagnostic et systeme integres de traitement de maladies
CA2285189A1 (fr) Systeme d'acquisition d'images d'un fluide en plusieurs phases par mesure de la lumiere retrodiffusee
NO20021626D0 (no) Optimalisering av en fiberoptisk probe for spektroskopiske målinger
WO2006053273A3 (fr) Procede et systeme de detection a fibre optique
WO2002063350A3 (fr) Controle de guide d'ondes optiques
CA2209240A1 (fr) Coupleur optique pour un examen in vivo de tissus biologiques
WO2003025546A3 (fr) Spectrometre a filtrage integre adapte a des signaux
AU2002355084A1 (en) Fiber optic laser detection and ranging system
WO2008100895A3 (fr) Système polyvalent de multidétection pour microplaques
FR2820550B1 (fr) Amplificateur de raman et systeme de transmission optique utilisant l'amplificateur
AU2001291121A1 (en) Wavelength detector and method of detecting wavelength of an optical signal
AU6144501A (en) Determination of the ultrastructure of connective tissue by an infrared fiber-optic spectroscopic probe
CA2198593A1 (fr) Capteurs optiques et procede de production de capteurs a detection de mode pour fibres optiques
Chen et al. Dual-modality optical coherence tomography and frequency-domain fluorescence lifetime imaging microscope system for intravascular imaging
AU4181499A (en) Method and system for determining the wavelength of light transmitted through anoptical fiber
CN109564327B (zh) 环形光束耦合系统
AU2003258523A1 (en) Device for the ir-spectrometric analysis of a solid, liquid or gaseous medium
WO2003010561A3 (fr) Coupleur optique destine a mesurer la fluorescence des tissus
JP2008046574A (ja) 周波数可変テラヘルツ波内視鏡
WO2006039360A3 (fr) Spectrographe a infrarouge et methode pour diagnostiquer une maladie

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ PL PT RO RU SE SG SI SK SL TJ TM TR TT TZ UA US UZ VN YU

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE BF BJ CF CG CI CM GA GQ GW ML MR NE SN TD TG

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP