[go: up one dir, main page]

WO2003011859A3 - Derives oxazolidinones utilises en tant qu'agents antibacteriens - Google Patents

Derives oxazolidinones utilises en tant qu'agents antibacteriens Download PDF

Info

Publication number
WO2003011859A3
WO2003011859A3 PCT/GB2002/003404 GB0203404W WO03011859A3 WO 2003011859 A3 WO2003011859 A3 WO 2003011859A3 GB 0203404 W GB0203404 W GB 0203404W WO 03011859 A3 WO03011859 A3 WO 03011859A3
Authority
WO
WIPO (PCT)
Prior art keywords
alkyl
antibacterial agents
substituted
oxazolidinone derivatives
group
Prior art date
Application number
PCT/GB2002/003404
Other languages
English (en)
Other versions
WO2003011859A2 (fr
Inventor
Yusuf Khwaja Hamied
Vithal Madhvarao Kulkarni
Original Assignee
Cipla Ltd
Yusuf Khwaja Hamied
Vithal Madhvarao Kulkarni
Wain Christopher Paul
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd, Yusuf Khwaja Hamied, Vithal Madhvarao Kulkarni, Wain Christopher Paul filed Critical Cipla Ltd
Publication of WO2003011859A2 publication Critical patent/WO2003011859A2/fr
Publication of WO2003011859A3 publication Critical patent/WO2003011859A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés d'oxazolidine représentés par la formule générale suivante, dans laquelle R1 comprend au moins un groupe phényle substitué ou non et au moins un groupe hétérocyclique insaturé substitué ou non, possédant au moins deux hétéroatomes ; et R2 représente un groupe imide, alkylidène, alkyle, halogène, alcanoyloxy, phosphate, arylsulphonate substitué ou ammonium, un hétérocycle saturé ou insaturé, H, OR3, N3 ou NHR4, R3=H, alkyle C¿1?-C4, SO2(C1-C4)alkyle ; R?4¿=H, alkyle C¿1?-C4, C(=O)(C1-C4)alkyle.
PCT/GB2002/003404 2001-07-27 2002-07-25 Derives oxazolidinones utilises en tant qu'agents antibacteriens WO2003011859A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0118407.6 2001-07-27
GBGB0118407.6A GB0118407D0 (en) 2001-07-27 2001-07-27 Oxazolidinone derivatives as antibacterial agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/719,232 Continuation US6908013B2 (en) 2001-05-25 2003-11-20 Tamper-evident device

Publications (2)

Publication Number Publication Date
WO2003011859A2 WO2003011859A2 (fr) 2003-02-13
WO2003011859A3 true WO2003011859A3 (fr) 2003-04-03

Family

ID=9919346

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/003404 WO2003011859A2 (fr) 2001-07-27 2002-07-25 Derives oxazolidinones utilises en tant qu'agents antibacteriens

Country Status (2)

Country Link
GB (1) GB0118407D0 (fr)
WO (1) WO2003011859A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU52403A (sh) 2000-12-26 2006-03-03 Dr.Reddy's Research Foundation Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže
US7160912B2 (en) 2000-12-26 2007-01-09 Dr.Reddy's Laboratories Ltd. Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them
IL160739A0 (en) 2001-09-11 2004-08-31 Astrazeneca Ab Oxazolidinone and/or isoxazoline as antibacterial agents
EP2181994B1 (fr) 2006-03-31 2014-05-28 Research Foundation Itsuu Laboratory Composés antimicrobiens
TW200815428A (en) 2006-08-15 2008-04-01 Wyeth Corp Oxazolidone derivatives as PR modulators
WO2008021338A2 (fr) 2006-08-15 2008-02-21 Wyeth Dérivés d'oxazolidone tricycliques utiles en tant que modulateurs du récepteur de la progestérone
WO2008021309A1 (fr) 2006-08-15 2008-02-21 Wyeth Dérivés d'imidazolidin-2-one utiles en tant que modulateurs pr
WO2008021337A1 (fr) 2006-08-15 2008-02-21 Wyeth Dérivés oxazinan-2-one utiles comme modulateurs pr
US7649007B2 (en) 2006-08-15 2010-01-19 Wyeth Llc Oxazolidine derivatives as PR modulators
EP2208729A4 (fr) 2007-10-02 2011-04-27 Res Found Itsuu Lab Dérivé d'oxazolidinone avec hétérocycle à 7 chaînons
CN116423599B (zh) * 2023-05-29 2024-06-25 德华兔宝宝装饰新材股份有限公司 抗菌阻燃木单板及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359418A1 (fr) * 1988-09-15 1990-03-21 The Upjohn Company 5-Indolinyl-5-bêta amidométhyloxazolidines-2-one, 3-(phényl condensé)-5 bêta amidométhyloxazolidines-2-ones et 3-phényl-azoté-5 bêta amidométhyloxazolidine 2-one
EP0693491A1 (fr) * 1994-07-20 1996-01-24 Bayer Ag Oxazolidinones substituées par un groupe hétéroaryle à 5 chaínons comme médicament anti-bactérien
WO1997021708A1 (fr) * 1995-12-13 1997-06-19 Pharmacia & Upjohn Company Derives de 4-pyrimidinyl- ou 4-pyrazinyl-piperazinyl-phenyl-oxazolidinone, leur preparation et leur emploi comme agents antibacteriens
WO1999002525A1 (fr) * 1997-07-11 1999-01-21 Pharmacia & Upjohn Company Agents antibacteriens de type phenyloxazolidinones de thiadiazolyle et d'oxadiazolyle

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359418A1 (fr) * 1988-09-15 1990-03-21 The Upjohn Company 5-Indolinyl-5-bêta amidométhyloxazolidines-2-one, 3-(phényl condensé)-5 bêta amidométhyloxazolidines-2-ones et 3-phényl-azoté-5 bêta amidométhyloxazolidine 2-one
EP0693491A1 (fr) * 1994-07-20 1996-01-24 Bayer Ag Oxazolidinones substituées par un groupe hétéroaryle à 5 chaínons comme médicament anti-bactérien
WO1997021708A1 (fr) * 1995-12-13 1997-06-19 Pharmacia & Upjohn Company Derives de 4-pyrimidinyl- ou 4-pyrazinyl-piperazinyl-phenyl-oxazolidinone, leur preparation et leur emploi comme agents antibacteriens
WO1999002525A1 (fr) * 1997-07-11 1999-01-21 Pharmacia & Upjohn Company Agents antibacteriens de type phenyloxazolidinones de thiadiazolyle et d'oxadiazolyle

Also Published As

Publication number Publication date
GB0118407D0 (en) 2001-09-19
WO2003011859A2 (fr) 2003-02-13

Similar Documents

Publication Publication Date Title
NO20013379D0 (no) 4-okso-1,4-dihydro-3-kinolinkarboksamider som antivirusmidler
TR200401772T4 (tr) hPPAR alfa aktivatörleri olarak ikame edilmiş oksazol ve tiyazol türevleri.
WO2000075113A8 (fr) Nouveaux derives carboxamide heterocycliques
PT931788E (pt) Inibidores de metaloprotease
WO2001077107A8 (fr) Production et utilisation de composes heterocycliques
CA2378183A1 (fr) Phenyl-oxazolidinones substitutees heterobicycliques antibacteriennes
WO2000047580A3 (fr) Derives de phenyluree et de phenylthiouree
AU7372191A (en) 3,5-di-tertiarybutyl-4-hydroxyphenylemethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
PT1294724E (pt) Compostos pirrolo (2,3-d ) pirimidina como agentes imunosupressivos
WO2003011859A3 (fr) Derives oxazolidinones utilises en tant qu'agents antibacteriens
ES2177058T3 (es) Compuestos eter piperidinilaminometil trifluorometil ciclicos como antagonistas de la sustancia p.
BG105027A (en) Herbicidal mixture containing a 3 heterocyclyl-substituted benzoyl derivative
AU7927591A (en) Substituted aminoalkylbiphenyl derivatives
PT918776E (pt) Sintese total de acilfulvenos antitumorais
WO2002028844A1 (fr) Dérivés thiazole ou oxazole
KR870010054A (ko) 제초제
DE68927311D1 (de) Buten- oder Propensäure-Derivate
EP1357124A4 (fr) Composes heterocycliques et compositions ameliorant les fonctions cerebrales contenant ces derniers comme principe actif
ATE141272T1 (de) Beta-lactam-verbindungen und ihre herstellung
ES2093091T3 (es) Derivado de glutation.
NZ326675A (en) Oxazoline arthropodicides
DK0806413T3 (da) 2-substituerede viatmin D3-derivater
AU740079C (en) Antirheumatic agents
ES2140524T3 (es) Derivados de metotrexato.
EP1069115A4 (fr) Production de derives d'oxazolidin-2-one

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG US UZ VN YU ZA ZM

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP