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WO2003012065A3 - Kinases and phosphatases - Google Patents

Kinases and phosphatases Download PDF

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Publication number
WO2003012065A3
WO2003012065A3 PCT/US2002/024521 US0224521W WO03012065A3 WO 2003012065 A3 WO2003012065 A3 WO 2003012065A3 US 0224521 W US0224521 W US 0224521W WO 03012065 A3 WO03012065 A3 WO 03012065A3
Authority
WO
WIPO (PCT)
Prior art keywords
kpp
phosphatases
kinases
polynucleotides
agonists
Prior art date
Application number
PCT/US2002/024521
Other languages
French (fr)
Other versions
WO2003012065A2 (en
Inventor
Mariah R Baughn
Henry Yue
Narinder K Chawla
Ann He
Janice K Au-Young
Soo Yeun Lee
Kimberly J Gietzen
Preeti G Lal
Vicki S Elliott
Craig H Ison
Junming Yang
Ernestine A Lee
Joana X Li
Brooke M Emerling
Thomas W Richardson
Bridget A Warren
April J A Hafalia
Joseph P Marquis
Original Assignee
Incyte Genomics Inc
Mariah R Baughn
Henry Yue
Narinder K Chawla
Ann He
Janice K Au-Young
Soo Yeun Lee
Kimberly J Gietzen
Preeti G Lal
Vicki S Elliott
Craig H Ison
Junming Yang
Ernestine A Lee
Joana X Li
Brooke M Emerling
Thomas W Richardson
Bridget A Warren
April J A Hafalia
Joseph P Marquis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Mariah R Baughn, Henry Yue, Narinder K Chawla, Ann He, Janice K Au-Young, Soo Yeun Lee, Kimberly J Gietzen, Preeti G Lal, Vicki S Elliott, Craig H Ison, Junming Yang, Ernestine A Lee, Joana X Li, Brooke M Emerling, Thomas W Richardson, Bridget A Warren, April J A Hafalia, Joseph P Marquis filed Critical Incyte Genomics Inc
Priority to AU2002327419A priority Critical patent/AU2002327419A1/en
Publication of WO2003012065A2 publication Critical patent/WO2003012065A2/en
Publication of WO2003012065A3 publication Critical patent/WO2003012065A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
PCT/US2002/024521 2001-08-02 2002-08-01 Kinases and phosphatases WO2003012065A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002327419A AU2002327419A1 (en) 2001-08-02 2002-08-01 Kinases and phosphatases

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US30962701P 2001-08-02 2001-08-02
US60/309,627 2001-08-02
US31093301P 2001-08-07 2001-08-07
US60/310,933 2001-08-07
US31132301P 2001-08-09 2001-08-09
US60/311,323 2001-08-09
US31782001P 2001-09-07 2001-09-07
US60/317,820 2001-09-07
US32226401P 2001-09-14 2001-09-14
US60/322,264 2001-09-14
US32609801P 2001-09-28 2001-09-28
US60/326,098 2001-09-28
US34300701P 2001-12-19 2001-12-19
US60/343,007 2001-12-19
US36449402P 2002-03-15 2002-03-15
US60/364,494 2002-03-15
US37553902P 2002-04-24 2002-04-24
US60/375,539 2002-04-24

Publications (2)

Publication Number Publication Date
WO2003012065A2 WO2003012065A2 (en) 2003-02-13
WO2003012065A3 true WO2003012065A3 (en) 2004-04-01

Family

ID=27578796

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/024521 WO2003012065A2 (en) 2001-08-02 2002-08-01 Kinases and phosphatases

Country Status (2)

Country Link
AU (1) AU2002327419A1 (en)
WO (1) WO2003012065A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8029986B2 (en) 2004-10-21 2011-10-04 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt(GmbH) KASPP (LRRK2) gene, its production and use for the detection and treatment of neurodegenerative disorders

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"Catalog Item G5149", 1993, SIGMA CHEMICAL COMPANY, article "Item G5149 is a bioactive peptide of Gly-Gln", pages: 1067, XP002972718 *
DATABASE GENBANK [online] 2001, MUKHERJEE ET AL., XP002972713, accession no. EMBL Database accession no. (Q91Z80) *
DATABASE GENBANK [online] SCHOCH ET AL.: "RIMA alpha forms a protein scaffold for regulating neurotransmitter release at the active zone", XP002972714, Database accession no. (AY057064) *
NATURE, vol. 415, no. 6869, 2002, pages 321 - 326 *

Also Published As

Publication number Publication date
AU2002327419A1 (en) 2003-02-17
WO2003012065A2 (en) 2003-02-13

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