[go: up one dir, main page]

WO2003018841A1 - Procede de determination d'un mesappariement entre des molecules d'acide nucleique monobrin - Google Patents

Procede de determination d'un mesappariement entre des molecules d'acide nucleique monobrin Download PDF

Info

Publication number
WO2003018841A1
WO2003018841A1 PCT/JP2002/008448 JP0208448W WO03018841A1 WO 2003018841 A1 WO2003018841 A1 WO 2003018841A1 JP 0208448 W JP0208448 W JP 0208448W WO 03018841 A1 WO03018841 A1 WO 03018841A1
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
stranded nucleic
acid molecule
mismatch
acid molecules
Prior art date
Application number
PCT/JP2002/008448
Other languages
English (en)
French (fr)
Inventor
Atsushi Maruyama
Original Assignee
The Circle For The Promotion Of Science And Engineering
Nof Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Circle For The Promotion Of Science And Engineering, Nof Corporation filed Critical The Circle For The Promotion Of Science And Engineering
Priority to US10/487,248 priority Critical patent/US20040265823A1/en
Priority to JP2003523687A priority patent/JP4178194B2/ja
Priority to EP02762825A priority patent/EP1428890B1/en
Priority to DE60228100T priority patent/DE60228100D1/de
Publication of WO2003018841A1 publication Critical patent/WO2003018841A1/ja

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6832Enhancement of hybridisation reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PCT/JP2002/008448 2001-08-24 2002-08-22 Procede de determination d'un mesappariement entre des molecules d'acide nucleique monobrin WO2003018841A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US10/487,248 US20040265823A1 (en) 2001-08-24 2002-08-22 Method of judging mismatch between single-stranded nucleic acid molecules
JP2003523687A JP4178194B2 (ja) 2001-08-24 2002-08-22 単鎖核酸分子間のミスマッチ判定方法
EP02762825A EP1428890B1 (en) 2001-08-24 2002-08-22 Method of judging mismatch between single-stranded nucleic acid molecules
DE60228100T DE60228100D1 (de) 2001-08-24 2002-08-22 Verfahren zur beurteilung einer fehlpaarung zwischen einzelsträngigen nukleinsäuremolekülen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001253789 2001-08-24
JP2001-253789 2001-08-24

Publications (1)

Publication Number Publication Date
WO2003018841A1 true WO2003018841A1 (fr) 2003-03-06

Family

ID=19082055

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/008448 WO2003018841A1 (fr) 2001-08-24 2002-08-22 Procede de determination d'un mesappariement entre des molecules d'acide nucleique monobrin

Country Status (6)

Country Link
US (1) US20040265823A1 (ja)
EP (1) EP1428890B1 (ja)
JP (1) JP4178194B2 (ja)
CN (1) CN1332038C (ja)
DE (1) DE60228100D1 (ja)
WO (1) WO2003018841A1 (ja)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048404A3 (en) * 2000-12-14 2003-10-23 Gen Probe Inc Method and kit for enhancing the association rates of polynucleotides
JP2008278779A (ja) * 2007-05-09 2008-11-20 Asahi Kasei Corp 核酸ハイブリダイゼーション用溶液
JP2008307046A (ja) * 2007-05-11 2008-12-25 Asahi Kasei Corp 核酸分子間の鎖交換反応を促進させる方法
JP5843112B2 (ja) * 2010-03-29 2016-01-13 凸版印刷株式会社 標的塩基配列の識別方法
JPWO2019111838A1 (ja) * 2017-12-04 2021-01-14 日油株式会社 ソフトコンタクトレンズ用処理液
JPWO2023106190A1 (ja) * 2021-12-10 2023-06-15
WO2023106200A1 (ja) * 2021-12-10 2023-06-15 日東紡績株式会社 核酸の対象塩基配列中における変異を検出するための方法、核酸の増幅を選択的に阻害する方法、およびこれらを実施するためのキット
WO2023106189A1 (ja) * 2021-12-10 2023-06-15 日東紡績株式会社 核酸の融解温度(Tm値)上昇化剤
JPWO2023106198A1 (ja) * 2021-12-10 2023-06-15

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009009889A1 (en) * 2007-07-13 2009-01-22 National Research Council Of Canada Ultrasensitive detection of target using target-ready particles
WO2013122035A1 (ja) * 2012-02-17 2013-08-22 株式会社ファインテック 防カビエアフィルター濾材及び防カビエアフィルター

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752565A (en) * 1986-04-07 1988-06-21 The United States Of America As Represented By The Department Of Health And Human Services Cell line producing AIDS viral antigens without producing infectious virus particles
JP3638516B2 (ja) * 2000-09-28 2005-04-13 株式会社日立製作所 核酸検出方法および核酸検出キット
ATE447043T1 (de) * 2000-12-14 2009-11-15 Gen Probe Inc Verfahren und kits zur verbesserung der hybridisierungsraten von polynukleotiden
WO2002088389A1 (fr) * 2001-04-26 2002-11-07 Nof Corporation Inhibiteurs d'hybridation non specifiques, reactifs d'examen clinique et procede d'examen clinique

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
GELFAND C.A. ET AL.: "A quantitative method for evaluating the stabilities of nucleic acids", PROC. NATL. ACAD. SCI. USA, vol. 96, no. 11, 1989, pages 6113 - 6118, XP002925481 *
KIM W.J. ET AL.: "Comb-type cationic copolymer expedites DNA strand exchange while stabilizing DNA duplex", CHE. EUR. J., vol. 7, no. 1, January 2001 (2001-01-01), pages 176 - 180, XP002960295 *
KIN ENSHO ET AL.: "Cation-sei graft kyo jugotai ni yoru DNA-sa kokan han'no no kasoku", BIO KOBUNSHI SYMPOSIUM KOEN YOSHISHU, vol. 10, 2000, pages 67 - 68, XP002960294 *
KIN ENSHO ET AL.: "Polycation kyo jugotai no DNA-sa kokan sokushin koka", BIO KOBUNSHI SYMPOSIUM KOEN YOSHISHU, vol. 11, July 2001 (2001-07-01), pages 41 - 42, XP002960293 *
MANAMI UEDA ET AL.: "Polycation kushigata kyo jugotai ni yoru sanjusa DNA no anteika kiko no kaiseki", POLYMER PREPRINTS, JAPAN, vol. 50, no. 5, May 2001 (2001-05-01), pages 990 *
See also references of EP1428890A4 *
SHUJIRO SAKAKI ET AL.: "MPC polymer ni yoru 1 enki takata (SNPs) no kokateki na ninshiki", POLYMER PREPRINTS, JAPAN, vol. 50, no. 5, May 2001 (2001-05-01), pages 992, XP002960296 *

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048404A3 (en) * 2000-12-14 2003-10-23 Gen Probe Inc Method and kit for enhancing the association rates of polynucleotides
US7374945B2 (en) 2000-12-14 2008-05-20 Gen-Probe Incorporated Method for enhancing the association rates of polynucleotides
JP2008278779A (ja) * 2007-05-09 2008-11-20 Asahi Kasei Corp 核酸ハイブリダイゼーション用溶液
JP2008307046A (ja) * 2007-05-11 2008-12-25 Asahi Kasei Corp 核酸分子間の鎖交換反応を促進させる方法
JP5843112B2 (ja) * 2010-03-29 2016-01-13 凸版印刷株式会社 標的塩基配列の識別方法
JPWO2019111838A1 (ja) * 2017-12-04 2021-01-14 日油株式会社 ソフトコンタクトレンズ用処理液
JP7228119B2 (ja) 2017-12-04 2023-02-24 日油株式会社 ソフトコンタクトレンズ用処理液
JPWO2023106190A1 (ja) * 2021-12-10 2023-06-15
WO2023106200A1 (ja) * 2021-12-10 2023-06-15 日東紡績株式会社 核酸の対象塩基配列中における変異を検出するための方法、核酸の増幅を選択的に阻害する方法、およびこれらを実施するためのキット
WO2023106190A1 (ja) * 2021-12-10 2023-06-15 日東紡績株式会社 二本鎖核酸の融解温度上昇化剤及びその用途
WO2023106189A1 (ja) * 2021-12-10 2023-06-15 日東紡績株式会社 核酸の融解温度(Tm値)上昇化剤
JPWO2023106189A1 (ja) * 2021-12-10 2023-06-15
JPWO2023106198A1 (ja) * 2021-12-10 2023-06-15
WO2023106198A1 (ja) * 2021-12-10 2023-06-15 日東紡績株式会社 核酸の対象塩基配列中における変異を検出するための方法、核酸の増幅を選択的に阻害する方法、およびこれらを実施するためのキット
JPWO2023106200A1 (ja) * 2021-12-10 2023-06-15
JP7394301B2 (ja) 2021-12-10 2023-12-08 日東紡績株式会社 二本鎖核酸の融解温度上昇化剤及びその用途
JP7421718B2 (ja) 2021-12-10 2024-01-25 日東紡績株式会社 核酸の対象塩基配列中における変異を検出するための方法、核酸の増幅を選択的に阻害する方法、およびこれらを実施するためのキット
JP7428951B2 (ja) 2021-12-10 2024-02-07 日東紡績株式会社 核酸の対象塩基配列中における変異を検出するための方法、核酸の増幅を選択的に阻害する方法、およびこれらを実施するためのキット
JP7453602B2 (ja) 2021-12-10 2024-03-21 日東紡績株式会社 核酸の融解温度(Tm値)上昇化剤
KR20240099441A (ko) 2021-12-10 2024-06-28 니토 보세키 가부시기가이샤 2 본쇄 핵산의 융해 온도 상승화제 및 그 용도
KR20240099468A (ko) 2021-12-10 2024-06-28 니토 보세키 가부시기가이샤 핵산의 융해 온도 (Tm 값) 상승화제
CN118382707A (zh) * 2021-12-10 2024-07-23 日东纺绩株式会社 双链核酸的融解温度升高化剂及其用途
KR102728359B1 (ko) 2021-12-10 2024-11-11 니토 보세키 가부시기가이샤 2 본쇄 핵산의 융해 온도 상승화제 및 그 용도
KR102728360B1 (ko) 2021-12-10 2024-11-11 니토 보세키 가부시기가이샤 핵산의 융해 온도 (Tm 값) 상승화제

Also Published As

Publication number Publication date
EP1428890B1 (en) 2008-08-06
US20040265823A1 (en) 2004-12-30
CN1547616A (zh) 2004-11-17
CN1332038C (zh) 2007-08-15
EP1428890A1 (en) 2004-06-16
JPWO2003018841A1 (ja) 2004-12-16
EP1428890A4 (en) 2006-06-07
DE60228100D1 (de) 2008-09-18
JP4178194B2 (ja) 2008-11-12

Similar Documents

Publication Publication Date Title
WO2003018841A1 (fr) Procede de determination d'un mesappariement entre des molecules d'acide nucleique monobrin
WO2005053603A3 (en) Antigen receptor variable region typing
WO2004072238A3 (en) Terminal-phosphate-labeled nucleotides with new linkers
WO2004067779A8 (en) Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
WO2006117161A3 (en) New labelling strategies for the sensitive detection of analytes
WO2005017025A3 (en) Study of polymer molecules and conformations with a nanopore
WO2006137932A3 (en) Homogeneous analyte detection
WO2002061133A3 (en) Nucleic acid detection using structured probes
WO2005043127A3 (en) Fluorescent probes for dna detection by hybridization with improved sensitivity and low background
EP1484416A3 (en) Method of identifying and quantifying specific fungi and bacteria
WO2007035864A3 (en) Electrophoresis standards, methods and kits
WO2001025480A3 (en) Dna sequencing method
WO2005111235A3 (en) Methods for detecting chromosome aberrations
WO2006078660A3 (en) Nucleic acid enzyme ligation sensor
WO2004111271A3 (en) Means and method for the detection of target nucleotide sequences using ligation assays with improved oligonucleotide probe pairs
WO2004081187A8 (en) Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof
WO2005054438A3 (en) Nucleic acid molecules containing recombination sites and methods of using the same
MXPA03000340A (es) Ensayo de hibridizacion triple mediada por cation.
WO2003033729A1 (fr) Procede de pretraitement d'echantillon pour la mesure d'une amine saccharifiee et procede de mesure d'une amine saccharifiee
WO2004083403A3 (en) Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
AU2001283901A1 (en) Competitive assay method
WO2004000995A3 (en) Methods, probes, and accessory molecules for detecting single nucleotide polymorphisms
WO2010059914A8 (en) Nucleic acid quantification products and processes
WO2002053771A3 (de) Nachweis von pathogenen bakterien
WO2001023605A3 (de) Verfahren und nukleinsäuren zum nachweis von brauereirelevanten mikroorganismen

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG US UZ VC VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2003523687

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 10487248

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 20028166035

Country of ref document: CN

WWE Wipo information: entry into national phase

Ref document number: 2002762825

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002762825

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2002762825

Country of ref document: EP