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WO2003018815A3 - Regulation de la grk humaine - Google Patents

Regulation de la grk humaine Download PDF

Info

Publication number
WO2003018815A3
WO2003018815A3 PCT/EP2002/009235 EP0209235W WO03018815A3 WO 2003018815 A3 WO2003018815 A3 WO 2003018815A3 EP 0209235 W EP0209235 W EP 0209235W WO 03018815 A3 WO03018815 A3 WO 03018815A3
Authority
WO
WIPO (PCT)
Prior art keywords
human
protein
regulation
receptor kinase
couple receptor
Prior art date
Application number
PCT/EP2002/009235
Other languages
English (en)
Other versions
WO2003018815A2 (fr
Inventor
Yonghong Xiao
Original Assignee
Bayer Ag
Yonghong Xiao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Yonghong Xiao filed Critical Bayer Ag
Priority to AU2002324058A priority Critical patent/AU2002324058A1/en
Publication of WO2003018815A2 publication Critical patent/WO2003018815A2/fr
Publication of WO2003018815A3 publication Critical patent/WO2003018815A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des réactifs qui régulent la GRK humaine et des réactifs qui se lient à des produits géniques de la GRK humaine et peuvent jouer un rôle de prévention, d'amélioration ou de correction de dysfonctionnements ou de maladies tels que, mais pas exclusivement, le cancer, le diabète, les troubles du système nerveux central, les troubles cardiovasculaires, l'asthme ou la BPCO.
PCT/EP2002/009235 2001-08-21 2002-08-19 Regulation de la grk humaine WO2003018815A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002324058A AU2002324058A1 (en) 2001-08-21 2002-08-19 Regulation of human g protein-couple receptor kinase

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31346401P 2001-08-21 2001-08-21
US60/313,464 2001-08-21

Publications (2)

Publication Number Publication Date
WO2003018815A2 WO2003018815A2 (fr) 2003-03-06
WO2003018815A3 true WO2003018815A3 (fr) 2003-10-30

Family

ID=23215795

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/009235 WO2003018815A2 (fr) 2001-08-21 2002-08-19 Regulation de la grk humaine

Country Status (2)

Country Link
AU (1) AU2002324058A1 (fr)
WO (1) WO2003018815A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030153525A1 (en) * 2001-12-19 2003-08-14 Millennium Pharmaceuticals, Inc. Methods and compositions in treating pain and painful disorders using 1465, 1587, 2146, 2207, 32838, 336 and 52908
WO2005114200A1 (fr) * 2004-05-21 2005-12-01 Bayer Healthcare Ag Diagnostic et therapeutique de pathologies en rapport avec une kinase 7 associee au recepteur couple a une proteine g (grk7)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001038503A2 (fr) * 1999-11-24 2001-05-31 Sugen, Inc. Nouvelles proteines kinases humaines et enzymes analogues
WO2001068869A2 (fr) * 2000-03-10 2001-09-20 Lexicon Genetics Incorporated Nouveaux recepteurs kinases couples a la proteine g et polynucleotides les codant
WO2001092496A2 (fr) * 2000-06-01 2001-12-06 Applera Corporation Proteines kinases humaines isolees, molecules d'acide nucleique codant pour ces proteines kinases humaines et utilisations de celles-ci
WO2001096547A2 (fr) * 2000-06-15 2001-12-20 Incyte Genomics, Inc. Kinases humaines
WO2002050105A1 (fr) * 2000-12-19 2002-06-27 Smithkline Beecham Corporation Composes

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001038503A2 (fr) * 1999-11-24 2001-05-31 Sugen, Inc. Nouvelles proteines kinases humaines et enzymes analogues
WO2001068869A2 (fr) * 2000-03-10 2001-09-20 Lexicon Genetics Incorporated Nouveaux recepteurs kinases couples a la proteine g et polynucleotides les codant
WO2001092496A2 (fr) * 2000-06-01 2001-12-06 Applera Corporation Proteines kinases humaines isolees, molecules d'acide nucleique codant pour ces proteines kinases humaines et utilisations de celles-ci
WO2001096547A2 (fr) * 2000-06-15 2001-12-20 Incyte Genomics, Inc. Kinases humaines
WO2002050105A1 (fr) * 2000-12-19 2002-06-27 Smithkline Beecham Corporation Composes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEN C K ET AL: "Characterization of human GRK7 as a potential cone opsin kinase.", MOLECULAR VISION US, vol. 7, 21 December 2001 (2001-12-21), pages 305 - 313, XP002240784, ISSN: 1090-0535 *
WEISS E R ET AL: "Species-specific differences in expression of G-protein-coupled receptor kinase (GRK) 7 and GRK1 in mammalian cone photoreceptor cells: implications for cone cell phototransduction.", THE JOURNAL OF NEUROSCIENCE: THE OFFICIAL JOURNAL OF THE SOC. FOR NEUROSCIENCE. US, vol. 21, no. 23, 1 December 2001 (2001-12-01), pages 9175 - 9184, XP002240783, ISSN: 1529-2401 *
WEISS E R ET AL: "The cloning of GRK7, a candidate cone opsin kinase, from cone- and rod-dominant mammalian retinas.", MOLECULAR VISION. US, vol. 4, 8 December 1998 (1998-12-08), pages 27 - 34, XP002240782, ISSN: 1090-0535 *

Also Published As

Publication number Publication date
AU2002324058A1 (en) 2003-03-10
WO2003018815A2 (fr) 2003-03-06

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