WO2003033664A9 - Composes agissant contre la resorption osseuse - Google Patents

Composes agissant contre la resorption osseuse Download PDF

Info

Publication number: WO2003033664A9
Authority: WO; WIPO (PCT)
Prior art keywords: bone anti; resorptive compounds; resorptive; compounds; bone
Prior art date: 2001-10-15

Application number

PCT/US2002/033047

Other languages

English (en)

Other versions

WO2003033664A2 (fr

Inventor

Jonathan Lam

F. Patrick Ross

Steven L. Teitelbaum

Original Assignee

Barnes-Jewish Hospital

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-15

Filing date

2002-10-15

Publication date

2013-11-07

2002-10-15 Application filed by Barnes-Jewish Hospital filed Critical Barnes-Jewish Hospital

2002-10-15 Priority to MXPA04003527A priority Critical patent/MXPA04003527A/es

2002-10-15 Priority to EP02782164A priority patent/EP1572891A2/fr

2002-10-15 Priority to CA002463925A priority patent/CA2463925A1/fr

2002-10-15 Priority to IL16138602A priority patent/IL161386A0/xx

2002-10-15 Priority to JP2003536394A priority patent/JP2005514919A/ja

2003-04-24 Publication of WO2003033664A2 publication Critical patent/WO2003033664A2/fr

2013-11-07 Publication of WO2003033664A9 publication Critical patent/WO2003033664A9/fr

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Physical Education & Sports Medicine (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Biophysics (AREA)
Rheumatology (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
General Engineering & Computer Science (AREA)
Toxicology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)

PCT/US2002/033047 2001-10-15 2002-10-15 Composes agissant contre la resorption osseuse WO2003033664A2 (fr)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
MXPA04003527A MXPA04003527A (es)	2001-10-15	2002-10-15	Compuestos de antiresorcion osea.
EP02782164A EP1572891A2 (fr)	2001-10-15	2002-10-15	Composes agissant contre la resorption osseuse
CA002463925A CA2463925A1 (fr)	2001-10-15	2002-10-15	Composes agissant contre la resorption osseuse
IL16138602A IL161386A0 (en)	2001-10-15	2002-10-15	Bone anti-resorptive compounds
JP2003536394A JP2005514919A (ja)	2001-10-15	2002-10-15	骨抗吸収化合物

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US32936001P	2001-10-15	2001-10-15
US60/329,360		2001-10-15

Publications (2)

Publication Number	Publication Date
WO2003033664A2 WO2003033664A2 (fr)	2003-04-24
WO2003033664A9 true WO2003033664A9 (fr)	2013-11-07

Family

ID=23285025

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PCT/US2002/033047 WO2003033664A2 (fr)	2001-10-15	2002-10-15	Composes agissant contre la resorption osseuse

Country Status (7)

Country	Link
EP (1)	EP1572891A2 (fr)
JP (1)	JP2005514919A (fr)
CN (1)	CN1635849A (fr)
CA (1)	CA2463925A1 (fr)
IL (1)	IL161386A0 (fr)
MX (1)	MXPA04003527A (fr)
WO (1)	WO2003033664A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7381792B2 (en)	2002-01-04	2008-06-03	Xencor, Inc.	Variants of RANKL protein
EP1576088A4 (fr)	2002-01-04	2006-09-06	Xencor Inc	Proteines negatives dominantes et procedes associes
WO2006024096A1 (fr) *	2004-08-31	2006-03-09	Chemgenex Pharmaceuticals Limited	Procédé servant à moduler l'ostéoclastogénèse
FR2883873B1 (fr)	2005-03-31	2009-07-10	Pharmamens Sarl	Inhibiteurs d'age
RU2661677C2 (ru) *	2011-05-27	2018-07-18	Аблинкс Нв	Ингибирование резорбции кости с помощью связывающих rank-l пептидов
CA2986218C (fr) *	2015-05-20	2021-01-05	Osaka University	Oligopeptide ayant une activite d'inhibition de la secretion de cytokine pro-inflammatoire
WO2018084311A1 (fr) *	2016-11-07	2018-05-11	国立大学法人大阪大学	Agent prophylactique ou thérapeutique contre des maladies cutanées inflammatoires
CN119930759B (zh) *	2025-04-07	2025-07-25	湖南中晟全肽生物科技股份有限公司	抑制rank与rankl结合的多肽及其应用

2002
- 2002-10-15 IL IL16138602A patent/IL161386A0/xx unknown
- 2002-10-15 WO PCT/US2002/033047 patent/WO2003033664A2/fr active Search and Examination
- 2002-10-15 CN CNA028231252A patent/CN1635849A/zh active Pending
- 2002-10-15 CA CA002463925A patent/CA2463925A1/fr not_active Abandoned
- 2002-10-15 JP JP2003536394A patent/JP2005514919A/ja active Pending
- 2002-10-15 EP EP02782164A patent/EP1572891A2/fr not_active Withdrawn
- 2002-10-15 MX MXPA04003527A patent/MXPA04003527A/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2463925A1 (fr)	2003-04-24
WO2003033664A2 (fr)	2003-04-24
MXPA04003527A (es)	2005-06-20
EP1572891A2 (fr)	2005-09-14
CN1635849A (zh)	2005-07-06
IL161386A0 (en)	2004-09-27
JP2005514919A (ja)	2005-05-26

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AU2002360487A1 (en)	2003-06-17	Acyclovir-peptide analogs
AU2002315080A1 (en)	2004-04-30	Bone plates
AU2002359165A1 (en)	2003-06-30	Novel compounds
AUPR878201A0 (en)	2001-12-06	New compounds
AU2002251024A1 (en)	2003-03-20	Substituted fluoroalcoxyphenylsulfonylurea
AU2002321215A1 (en)	2003-05-22	Substituted 4-aminocyclohexanols
AU2002364901A1 (en)	2003-06-17	Object decontaminator
WO2003033664A9 (fr)	2013-11-07	Composes agissant contre la resorption osseuse
PL369829A1 (en)	2005-05-02	Substituted 1h-quinolin-2-one compounds
AUPR920301A0 (en)	2001-12-20	Neurologically-active compounds
AU2002249494A1 (en)	2002-10-15	Anti-proliferative 6-o-acyl-beta-d-glucosyl-beta-sitosterol compounds
AU2004201666B2 (en)	2006-03-23	4-Imidazolin-2-one compounds
AU2002346861A1 (en)	2003-05-12	Substituted 1h-quinolin-2-one compounds
AU2002363108A1 (en)	2003-05-06	4-imidazolin-2-one compounds
AU2002306300A1 (en)	2003-03-03	Azasugar compounds
AU2002337136A1 (en)	2003-04-22	Isocyanato-isocyano compounds
AU2002235881A1 (en)	2002-08-19	Compounds
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AU2002326569A1 (en)	2003-02-24	Fat accumulation-modulating compounds
AU2002308746A1 (en)	2002-11-25	Glare-directed imaging
AU2002317861A1 (en)	2003-01-29	Substituted benzo-nitro-heterocycles

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