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WO2003039348A3 - Molecules de signalisation intracellulaire - Google Patents

Molecules de signalisation intracellulaire Download PDF

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Publication number
WO2003039348A3
WO2003039348A3 PCT/US2002/036151 US0236151W WO03039348A3 WO 2003039348 A3 WO2003039348 A3 WO 2003039348A3 US 0236151 W US0236151 W US 0236151W WO 03039348 A3 WO03039348 A3 WO 03039348A3
Authority
WO
WIPO (PCT)
Prior art keywords
intracellular signaling
signaling molecules
intsig
polynucleotides
agonists
Prior art date
Application number
PCT/US2002/036151
Other languages
English (en)
Other versions
WO2003039348A2 (fr
Inventor
Amy E Kable
Anita Swarnakar
Ann E Gorvad
April J A Hafalia
Brendan M Duggan
Bridget A Warren
Brooke M Emerling
Craig H Ison
Danniel B Nguyen
Erika A Lindquist
Original Assignee
Incyte Genomics Inc
Amy E Kable
Anita Swarnakar
Ann E Gorvad
April J A Hafalia
Brendan M Duggan
Bridget A Warren
Brooke M Emerling
Craig H Ison
Danniel B Nguyen
Erika A Lindquist
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Amy E Kable, Anita Swarnakar, Ann E Gorvad, April J A Hafalia, Brendan M Duggan, Bridget A Warren, Brooke M Emerling, Craig H Ison, Danniel B Nguyen, Erika A Lindquist filed Critical Incyte Genomics Inc
Priority to AU2002350174A priority Critical patent/AU2002350174A1/en
Priority to EP02786702A priority patent/EP1504101A2/fr
Publication of WO2003039348A2 publication Critical patent/WO2003039348A2/fr
Publication of WO2003039348A3 publication Critical patent/WO2003039348A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Selon les modes de réalisation, cette invention concerne des molécules humaines de signalisation intracellulaire (INTSIG) et des polypeptides identifiant et codant INTSIG ; des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes ; et des méthodes de diagnostic, de traitement ou de prévention de troubles associés à une expression aberrante de INTSIG.
PCT/US2002/036151 2001-11-09 2002-11-07 Molecules de signalisation intracellulaire WO2003039348A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002350174A AU2002350174A1 (en) 2001-11-09 2002-11-07 Intracellular signaling molecules
EP02786702A EP1504101A2 (fr) 2001-11-09 2002-11-07 Molecules de signalisation intracellulaire

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US34447201P 2001-11-09 2001-11-09
US60/344,472 2001-11-09
US33455801P 2001-11-30 2001-11-30
US60/334,558 2001-11-30
US34029601P 2001-12-14 2001-12-14
US60/340,296 2001-12-14
US34355701P 2001-12-21 2001-12-21
US60/343,557 2001-12-21
US35042002P 2002-01-18 2002-01-18
US60/350,420 2002-01-18
US35192702P 2002-01-25 2002-01-25
US60/351,927 2002-01-25

Publications (2)

Publication Number Publication Date
WO2003039348A2 WO2003039348A2 (fr) 2003-05-15
WO2003039348A3 true WO2003039348A3 (fr) 2004-12-02

Family

ID=27559760

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/036151 WO2003039348A2 (fr) 2001-11-09 2002-11-07 Molecules de signalisation intracellulaire

Country Status (3)

Country Link
EP (1) EP1504101A2 (fr)
AU (1) AU2002350174A1 (fr)
WO (1) WO2003039348A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080274954A1 (en) * 2004-04-15 2008-11-06 Osamu Ohara Gene Encoding a Guanine Nucleotide Exchange Factor and Its Gene Product
JP2006212003A (ja) * 2005-02-07 2006-08-17 Univ Of Tokyo がん抑制遺伝子産物関連タンパク質
PH12013500629A1 (en) 2010-09-22 2019-10-11 Alios Biopharma Inc Substituted nucleotide analogs
US8980865B2 (en) 2011-12-22 2015-03-17 Alios Biopharma, Inc. Substituted nucleotide analogs
EP2827876A4 (fr) 2012-03-22 2015-10-28 Alios Biopharma Inc Combinaisons pharmaceutiques comprenant un analogue thionucléotidique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BARAN C.P. ET AL: "The Role of ROS and RNS in Regulating Life and Death of Blood Monocytes", CURRENT PHARMACEUTICAL DESIGN, vol. 10, no. 8, 2004, pages 855 - 866, XP002981281 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug

Also Published As

Publication number Publication date
WO2003039348A2 (fr) 2003-05-15
AU2002350174A1 (en) 2003-05-19
EP1504101A2 (fr) 2005-02-09

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