[go: up one dir, main page]

WO2004011365A3 - Micro-channel design features that facilitate centripetal fluid transfer - Google Patents

Micro-channel design features that facilitate centripetal fluid transfer Download PDF

Info

Publication number
WO2004011365A3
WO2004011365A3 PCT/US2003/022226 US0322226W WO2004011365A3 WO 2004011365 A3 WO2004011365 A3 WO 2004011365A3 US 0322226 W US0322226 W US 0322226W WO 2004011365 A3 WO2004011365 A3 WO 2004011365A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid transfer
features
micro
channel design
facilitate
Prior art date
Application number
PCT/US2003/022226
Other languages
French (fr)
Other versions
WO2004011365A2 (en
Inventor
Sean M Desmond
John Shigeura
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/336,274 external-priority patent/US7198759B2/en
Priority claimed from US10/336,706 external-priority patent/US7214348B2/en
Application filed by Applera Corp filed Critical Applera Corp
Priority to JP2005505600A priority Critical patent/JP2005533651A/en
Priority to EP03771636A priority patent/EP1534429A4/en
Priority to AU2003253944A priority patent/AU2003253944A1/en
Priority to CA002493700A priority patent/CA2493700A1/en
Publication of WO2004011365A2 publication Critical patent/WO2004011365A2/en
Publication of WO2004011365A3 publication Critical patent/WO2004011365A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)

Abstract

Microfluidic device (100) is formed in substrate (108) and can include input port (106) in fluid communication with input channel (104) connected to feed channel (110). The microfluidic devices have a plurality of specialized processing features that facilitate centripetal fluid transfer is also provided.
PCT/US2003/022226 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer WO2004011365A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2005505600A JP2005533651A (en) 2002-07-26 2003-07-16 Microchannel design features that facilitate fluid movement by centripetal force
EP03771636A EP1534429A4 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer
AU2003253944A AU2003253944A1 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer
CA002493700A CA2493700A1 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US39885102P 2002-07-26 2002-07-26
US60/398,851 2002-07-26
US39954802P 2002-07-30 2002-07-30
US60/399,548 2002-07-30
US36633003A 2003-01-03 2003-01-03
US10/336,706 2003-01-03
US10/336,274 US7198759B2 (en) 2002-07-26 2003-01-03 Microfluidic devices, methods, and systems
US10/336,706 US7214348B2 (en) 2002-07-26 2003-01-03 Microfluidic size-exclusion devices, systems, and methods
US10/336,274 2003-01-03
US10/366,330 2003-01-03

Publications (2)

Publication Number Publication Date
WO2004011365A2 WO2004011365A2 (en) 2004-02-05
WO2004011365A3 true WO2004011365A3 (en) 2004-06-10

Family

ID=31192473

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/022226 WO2004011365A2 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer

Country Status (5)

Country Link
EP (1) EP1534429A4 (en)
JP (1) JP2005533651A (en)
AU (1) AU2003253944A1 (en)
CA (1) CA2493700A1 (en)
WO (1) WO2004011365A2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD564667S1 (en) 2005-07-05 2008-03-18 3M Innovative Properties Company Rotatable sample processing disk
US7569186B2 (en) 2001-12-28 2009-08-04 3M Innovative Properties Company Systems for using sample processing devices
US7595200B2 (en) 2000-06-28 2009-09-29 3M Innovative Properties Company Sample processing devices and carriers
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US6720187B2 (en) 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
JP5131538B2 (en) * 2008-05-07 2013-01-30 セイコーエプソン株式会社 Reaction liquid filling method
JP5298718B2 (en) * 2008-09-12 2013-09-25 セイコーエプソン株式会社 Centrifugal device for filling biological sample reaction chip with reaction solution
CN101533005B (en) * 2009-04-14 2012-10-10 北京大学 Microflow distribution device, manufacturing method and application thereof
JP2014517291A (en) 2011-05-18 2014-07-17 スリーエム イノベイティブ プロパティズ カンパニー System and method for valve operation of a sample processing apparatus
JP2015031643A (en) * 2013-08-06 2015-02-16 ブラザー工業株式会社 Inspection chip
WO2024221269A1 (en) * 2023-04-26 2024-10-31 深圳华大智造科技股份有限公司 Slide and biochemical analysis device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020037499A1 (en) * 2000-06-05 2002-03-28 California Institute Of Technology Integrated active flux microfluidic devices and methods
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846396A (en) * 1994-11-10 1998-12-08 Sarnoff Corporation Liquid distribution system
DE69634490T2 (en) * 1995-12-05 2006-03-02 Tecan Trading Ag APPARATUS AND METHOD FOR MOVING FLUIDS BY CENTRIFUGAL ACCELERATION IN AUTOMATIC LABORATORY TREATMENT
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
WO2000000816A1 (en) * 1998-06-29 2000-01-06 Evotec Biosystems Ag Method and device for manipulating particles in microsystems
JP2002527250A (en) * 1998-10-13 2002-08-27 バイオマイクロ システムズ インコーポレイテッド Fluid circuit components based on passive hydrodynamics
AU1658100A (en) * 1998-11-20 2000-06-13 Analyticon Ag Biotechnologie Pharmazie Method and device for regulating individual sub-flows of a system for conveying fluid media
GB9828785D0 (en) * 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems
US6395232B1 (en) * 1999-07-09 2002-05-28 Orchid Biosciences, Inc. Fluid delivery system for a microfluidic device using a pressure pulse
JP2004501360A (en) * 2000-05-15 2004-01-15 テカン・トレーディング・アクチェンゲゼルシャフト Microfluidic devices and methods for high-throughput screening
US6627159B1 (en) * 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
CA2439627A1 (en) * 2001-03-19 2002-09-26 Gyros Ab Structural units that define fluidic functions
WO2002083310A2 (en) * 2001-04-13 2002-10-24 Nanostream, Inc. Microfluidic metering systems and methods
WO2003072255A1 (en) * 2002-02-23 2003-09-04 Nanostream, Inc. Microfluidic multi-splitter

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
US20020037499A1 (en) * 2000-06-05 2002-03-28 California Institute Of Technology Integrated active flux microfluidic devices and methods

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595200B2 (en) 2000-06-28 2009-09-29 3M Innovative Properties Company Sample processing devices and carriers
US7569186B2 (en) 2001-12-28 2009-08-04 3M Innovative Properties Company Systems for using sample processing devices
USD564667S1 (en) 2005-07-05 2008-03-18 3M Innovative Properties Company Rotatable sample processing disk
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Also Published As

Publication number Publication date
EP1534429A2 (en) 2005-06-01
WO2004011365A2 (en) 2004-02-05
JP2005533651A (en) 2005-11-10
AU2003253944A1 (en) 2004-02-16
EP1534429A4 (en) 2005-09-07
CA2493700A1 (en) 2004-02-05

Similar Documents

Publication Publication Date Title
WO2004011365A3 (en) Micro-channel design features that facilitate centripetal fluid transfer
WO2003045559A8 (en) Microfluidic devices with distributing inputs
WO2004052540A3 (en) Configurable microfluidic substrate assembly
WO2002099406A3 (en) Single molecule detection systems and methods
USD528215S1 (en) Chip carrier for biosensor
WO2006102321A3 (en) Fluid processing device with captured reagent beads
WO2007024485A3 (en) Microfluidic reduction of diffusion and complience effect in a fluid mixing region
AU2002326881A1 (en) Microfluidic device having a reduced number of input and output connections
TWI266586B (en) Heat pipe
CA2261869A1 (en) Integrated microfluidic devices
WO2003035909A3 (en) A method for detecting disease using a fluidic device
WO2001007159A3 (en) Integration of biochemical protocols in a continuous flow microfluidic device
WO2003084450A3 (en) Time or time-temperature indicating articles
WO2004098757A3 (en) Microfluidic mixing using flow pulsing
WO2007005853A3 (en) Compliant microfluidic sample processing disks
WO2003068670A3 (en) Microfluidic valve and system therefor
MXPA02011663A (en) Substrate with a reduced light-scattering, ultraphobic surface and a method for the production of the same.
WO2004042357A3 (en) Thermal micro-valves for micro-integrated devices
WO2004002878A3 (en) Microfluidic devices and methods with electrochemically actuated sample processing
WO2004045671A3 (en) Microstructure roller system
AU5811800A (en) Oil based drilling fluid and copolymer based on styrene, laurylm ethacrylate and(meth)acrylic acid
EP1479943A4 (en) Speed change device
WO2004077258A3 (en) System and method for structuring distributed applications
IL176467A0 (en) Edge wheel dry manifold
EP2281633A8 (en) Retaining microfluidic microcavity and other microfluidic structures

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2003771636

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2003253944

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2493700

Country of ref document: CA

Ref document number: 2005505600

Country of ref document: JP

WWP Wipo information: published in national office

Ref document number: 2003771636

Country of ref document: EP