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WO2006008173A3 - Pharmaceutical formulations for inhalation - Google Patents

Pharmaceutical formulations for inhalation Download PDF

Info

Publication number
WO2006008173A3
WO2006008173A3 PCT/EP2005/007991 EP2005007991W WO2006008173A3 WO 2006008173 A3 WO2006008173 A3 WO 2006008173A3 EP 2005007991 W EP2005007991 W EP 2005007991W WO 2006008173 A3 WO2006008173 A3 WO 2006008173A3
Authority
WO
WIPO (PCT)
Prior art keywords
inhalation
pharmaceutical formulations
salts
administration
active agent
Prior art date
Application number
PCT/EP2005/007991
Other languages
French (fr)
Other versions
WO2006008173A2 (en
Inventor
Michael Simon Anson
Derek Leslie Crookes
Harish Shivprasad Trivedi
Original Assignee
Glaxo Group Ltd
Michael Simon Anson
Derek Leslie Crookes
Harish Shivprasad Trivedi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Michael Simon Anson, Derek Leslie Crookes, Harish Shivprasad Trivedi filed Critical Glaxo Group Ltd
Publication of WO2006008173A2 publication Critical patent/WO2006008173A2/en
Publication of WO2006008173A3 publication Critical patent/WO2006008173A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to salts of a biodegradable polymeric sugars comprising acidic groups and a pharmaceutically active agent comprising one or more basic groups, and to pharmaceutical formulations of said salts adapted for administration by inhalation.
PCT/EP2005/007991 2004-07-22 2005-07-20 Pharmaceutical formulations for inhalation WO2006008173A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0416397.8 2004-07-22
GB0416397A GB0416397D0 (en) 2004-07-22 2004-07-22 Pharmaceutical formulations

Publications (2)

Publication Number Publication Date
WO2006008173A2 WO2006008173A2 (en) 2006-01-26
WO2006008173A3 true WO2006008173A3 (en) 2006-05-26

Family

ID=32922634

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/007991 WO2006008173A2 (en) 2004-07-22 2005-07-20 Pharmaceutical formulations for inhalation

Country Status (2)

Country Link
GB (1) GB0416397D0 (en)
WO (1) WO2006008173A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7928089B2 (en) 2003-09-15 2011-04-19 Vectura Limited Mucoactive agents for treating a pulmonary disease

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP2086641A2 (en) * 2006-10-26 2009-08-12 Boehringer Ingelheim International GmbH Egfr kinase inhibitor combinations for the treatment of respiratory and gastrointestinal disorders
EP1921070A1 (en) 2006-11-10 2008-05-14 Boehringer Ingelheim Pharma GmbH & Co. KG Bicyclic heterocycles, medicaments comprising them, their use and process for their preparation
CA2711637A1 (en) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines as kinase inhibitors
EA019709B1 (en) 2008-02-07 2014-05-30 Бёрингер Ингельхайм Интернациональ Гмбх Spirocyclic heterocycles and use thereof as medicaments
US8648191B2 (en) 2008-08-08 2014-02-11 Boehringer Ingelheim International Gmbh Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them
EP2400950B1 (en) 2009-02-26 2019-05-22 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
ES2551592T3 (en) 2011-02-25 2015-11-20 Novartis Ag Pyrazolo [1,5-a] pyridines as TRK inhibitors
CN117679423A (en) * 2022-09-05 2024-03-12 立生医药(苏州)有限公司 Inhaled pharmaceutical compositions for preventing or treating respiratory diseases

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0555898A2 (en) * 1985-04-05 1993-08-18 FIDIA S.p.A. Medicaments for non-topical use
JPH1180032A (en) * 1997-09-12 1999-03-23 Dai Ichi Seiyaku Co Ltd Composite
WO2002051380A1 (en) * 2000-12-22 2002-07-04 Audit Institute For Medical Services And Quality Assurance Gmbh Novel pharmaceutical composition consisting of water-soluble or poorly water-soluble active substances
EP1407776A1 (en) * 2002-10-10 2004-04-14 Giuseppe Petrigni A pharmaceutical colloidal preparation comprising hyaluronic acid biopolymers useful in the treatment of respiratory diseases

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0555898A2 (en) * 1985-04-05 1993-08-18 FIDIA S.p.A. Medicaments for non-topical use
JPH1180032A (en) * 1997-09-12 1999-03-23 Dai Ichi Seiyaku Co Ltd Composite
WO2002051380A1 (en) * 2000-12-22 2002-07-04 Audit Institute For Medical Services And Quality Assurance Gmbh Novel pharmaceutical composition consisting of water-soluble or poorly water-soluble active substances
EP1407776A1 (en) * 2002-10-10 2004-04-14 Giuseppe Petrigni A pharmaceutical colloidal preparation comprising hyaluronic acid biopolymers useful in the treatment of respiratory diseases

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 199922, Derwent World Patents Index; Class B04, AN 1999-261460 *
PATENT ABSTRACTS OF JAPAN vol. 1999, no. 08 30 June 1999 (1999-06-30) *
SURENDRAKUMAR K ET AL: "Sustained release of insulin from sodium hyaluronate based dry powder formulations after pulmonary delivery to beagle dogs", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 91, no. 3, 4 September 2003 (2003-09-04), pages 385 - 394, XP004447921, ISSN: 0168-3659 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7928089B2 (en) 2003-09-15 2011-04-19 Vectura Limited Mucoactive agents for treating a pulmonary disease

Also Published As

Publication number Publication date
WO2006008173A2 (en) 2006-01-26
GB0416397D0 (en) 2004-08-25

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