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WO2007066018A3 - Peptides qui peuvent se lier a la proteine nef et leurs applications pharmaceutiques - Google Patents

Peptides qui peuvent se lier a la proteine nef et leurs applications pharmaceutiques Download PDF

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Publication number
WO2007066018A3
WO2007066018A3 PCT/FR2006/002697 FR2006002697W WO2007066018A3 WO 2007066018 A3 WO2007066018 A3 WO 2007066018A3 FR 2006002697 W FR2006002697 W FR 2006002697W WO 2007066018 A3 WO2007066018 A3 WO 2007066018A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel peptides
biological use
peptides
biological
novel
Prior art date
Application number
PCT/FR2006/002697
Other languages
English (en)
Other versions
WO2007066018A2 (fr
Inventor
Daniel Baty
Yves Collette
Francoise Guerlesquin
Xavier Morelli
Isabelle Parrot
Stephan Arold
Serge Benichou
Original Assignee
Centre Nat Rech Scient
Daniel Baty
Yves Collette
Francoise Guerlesquin
Xavier Morelli
Isabelle Parrot
Stephan Arold
Serge Benichou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Daniel Baty, Yves Collette, Francoise Guerlesquin, Xavier Morelli, Isabelle Parrot, Stephan Arold, Serge Benichou filed Critical Centre Nat Rech Scient
Priority to EP06841902A priority Critical patent/EP1976862A2/fr
Priority to US12/086,243 priority patent/US20090163410A1/en
Priority to CA002632708A priority patent/CA2632708A1/fr
Publication of WO2007066018A2 publication Critical patent/WO2007066018A2/fr
Publication of WO2007066018A3 publication Critical patent/WO2007066018A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention a pour objet de nouveaux peptides isolés, purifiés, possédant notamment des propriétés de liaison à la protéine Nef, caractérisés en ce qu'ils renferment une séquence en acides aminés répondant à SEQ ID N°1 : W-P-a-W-L-P dans laquelle a est choisi parmi W, A, S ou D.
PCT/FR2006/002697 2005-12-09 2006-12-11 Peptides qui peuvent se lier a la proteine nef et leurs applications pharmaceutiques WO2007066018A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP06841902A EP1976862A2 (fr) 2005-12-09 2006-12-11 Nouveaux peptides et leurs applications biologiques
US12/086,243 US20090163410A1 (en) 2005-12-09 2006-12-11 Novel Peptides and the Biological Use Thereof
CA002632708A CA2632708A1 (fr) 2005-12-09 2006-12-11 Peptides qui peuvent se lier a la proteine nef et leurs applications pharmaceutiques

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0512524A FR2894584A1 (fr) 2005-12-09 2005-12-09 Nouveaux peptides et leurs applications biologiques
FR0512524 2005-12-09

Publications (2)

Publication Number Publication Date
WO2007066018A2 WO2007066018A2 (fr) 2007-06-14
WO2007066018A3 true WO2007066018A3 (fr) 2007-07-26

Family

ID=36570518

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2006/002697 WO2007066018A2 (fr) 2005-12-09 2006-12-11 Peptides qui peuvent se lier a la proteine nef et leurs applications pharmaceutiques

Country Status (5)

Country Link
US (1) US20090163410A1 (fr)
EP (1) EP1976862A2 (fr)
CA (1) CA2632708A1 (fr)
FR (1) FR2894584A1 (fr)
WO (1) WO2007066018A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2879605B1 (fr) 2004-12-16 2008-10-17 Centre Nat Rech Scient Cnrse Production de formats d'anticorps et applications immunologiques de ces formats
EP2062578A1 (fr) 2007-11-12 2009-05-27 Institut National De La Sante Et De La Recherche Medicale (Inserm) Utilisation de composés chimiques pour traiter le SIDA
CA2860226C (fr) 2011-12-22 2022-10-18 Randolph S. Watnick Peptides derives de saposine a et utilisations de ceux-ci
CN105358708B (zh) 2013-03-14 2024-07-16 儿童医学中心公司 Cd36鉴定癌症对象以用于治疗的用途

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999057136A2 (fr) * 1998-05-06 1999-11-11 Markus Schott Partenaire de liaison et procede pour assurer une inhibition competitive de la liaison entre une proteine de regulation nef et la calmoduline, agent contenant ledit partenaire de liaison et utilisation de ce dernier dans le cas de maladies provoquees par le vih
EP0965594A2 (fr) * 1998-06-15 1999-12-22 Nippon Zoki Pharmaceutical Co., Ltd. Proteine liant la Nef, ADN codifiant et anticorps monoclonal contre dite proteine
US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
US20030229906A1 (en) * 2002-04-15 2003-12-11 Gelman Irwin H. Methods and compositions for the treatment of disorders of HIV infection
WO2004050858A2 (fr) * 2002-12-04 2004-06-17 Diadexus, Inc. Compositions, variants d'epissage et procedes associe aux genes et proteines specifiques du colon
US20040123343A1 (en) * 2000-04-19 2004-06-24 La Rosa Thomas J. Rice nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20040172684A1 (en) * 2000-05-08 2004-09-02 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20040214272A1 (en) * 1999-05-06 2004-10-28 La Rosa Thomas J Nucleic acid molecules and other molecules associated with plants

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
WO1999057136A2 (fr) * 1998-05-06 1999-11-11 Markus Schott Partenaire de liaison et procede pour assurer une inhibition competitive de la liaison entre une proteine de regulation nef et la calmoduline, agent contenant ledit partenaire de liaison et utilisation de ce dernier dans le cas de maladies provoquees par le vih
EP0965594A2 (fr) * 1998-06-15 1999-12-22 Nippon Zoki Pharmaceutical Co., Ltd. Proteine liant la Nef, ADN codifiant et anticorps monoclonal contre dite proteine
US20040214272A1 (en) * 1999-05-06 2004-10-28 La Rosa Thomas J Nucleic acid molecules and other molecules associated with plants
US20040123343A1 (en) * 2000-04-19 2004-06-24 La Rosa Thomas J. Rice nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20040172684A1 (en) * 2000-05-08 2004-09-02 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20030229906A1 (en) * 2002-04-15 2003-12-11 Gelman Irwin H. Methods and compositions for the treatment of disorders of HIV infection
WO2004050858A2 (fr) * 2002-12-04 2004-06-17 Diadexus, Inc. Compositions, variants d'epissage et procedes associe aux genes et proteines specifiques du colon

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DUTARTRE H ET AL: "The Human Immunodeficiency Virus Type 1 NEF Protein Binds the Src-Related Tyrosine Kinase Lck SH2 Domain Through a Novel Phosphotyrosine Independent Mechanism", VIROLOGY, ACADEMIC PRESS,ORLANDO, US, vol. 247, no. 2, 1 August 1998 (1998-08-01), pages 200 - 211, XP004445738, ISSN: 0042-6822 *
M HIIPAKKA & K SAKSELA: "Capacity of simian immunodeficiency virus strain mac Nef for high affinity Src homology 3 (SH3) binding revealed by ligand-tailored SH3 domains", JOURNAL OF GENERAL VIROLOGY., vol. 83, no. 12, 2002, GB SOCIETY FOR GENERAL MICROBIOLOGY, SPENCERS WOOD., pages 3147 - 3152, XP002433860 *
M HIIPAKKA ET AL.: "SH3 domains with high affinity and engineered ligand specificities targeted to HIV-1 Nef", JOURNAL OF MOLECULAR BIOLOGY, vol. 293, 1999, GB LONDON, pages 1097 - 1106, XP004466235 *

Also Published As

Publication number Publication date
EP1976862A2 (fr) 2008-10-08
CA2632708A1 (fr) 2007-06-14
FR2894584A1 (fr) 2007-06-15
US20090163410A1 (en) 2009-06-25
WO2007066018A2 (fr) 2007-06-14

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