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WO2007011434A3 - Procedes destines a prevenir et a traiter des cancers qui expriment l'axe gonadal pituitaire ophtalmique d'hormones et de recepteurs - Google Patents

Procedes destines a prevenir et a traiter des cancers qui expriment l'axe gonadal pituitaire ophtalmique d'hormones et de recepteurs Download PDF

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Publication number
WO2007011434A3
WO2007011434A3 PCT/US2006/010668 US2006010668W WO2007011434A3 WO 2007011434 A3 WO2007011434 A3 WO 2007011434A3 US 2006010668 W US2006010668 W US 2006010668W WO 2007011434 A3 WO2007011434 A3 WO 2007011434A3
Authority
WO
WIPO (PCT)
Prior art keywords
treating
methods
hypothalamic
pituitary
hormones
Prior art date
Application number
PCT/US2006/010668
Other languages
English (en)
Other versions
WO2007011434A2 (fr
Inventor
Christopher W Gregory
Maria E Kononov
Eric S Werdin
James Lester Barbee Iv
Carol Giamario
Original Assignee
Voyager Pharmaceutical Corp
Christopher W Gregory
Maria E Kononov
Eric S Werdin
James Lester Barbee Iv
Carol Giamario
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/180,668 external-priority patent/US20060148697A1/en
Priority claimed from US11/180,667 external-priority patent/US20070015713A1/en
Application filed by Voyager Pharmaceutical Corp, Christopher W Gregory, Maria E Kononov, Eric S Werdin, James Lester Barbee Iv, Carol Giamario filed Critical Voyager Pharmaceutical Corp
Publication of WO2007011434A2 publication Critical patent/WO2007011434A2/fr
Publication of WO2007011434A3 publication Critical patent/WO2007011434A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des procédés destinés à traiter des cancers positifs à axe gonadotrophine hypophysaire (HPG), à prévenir ou à ralentir la prolifération de cellules d'origine cancéreuse positives à axe HPG, à prévenir les cancers positifs à axe HPG chez un patient à risque, à prévenir ou à inhiber la régulation positive du cycle cellulaire dans des cellules dérivées du cancer positif à axe HPG chez un patient, et à réduire le niveau de marqueurs spécifiques du cancer positif à axe HPG chez un patient.
PCT/US2006/010668 2005-07-14 2006-03-22 Procedes destines a prevenir et a traiter des cancers qui expriment l'axe gonadal pituitaire ophtalmique d'hormones et de recepteurs WO2007011434A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/180,668 2005-07-14
US11/180,668 US20060148697A1 (en) 2001-12-19 2005-07-14 Methods for treating and preventing brain cancers
US11/180,667 US20070015713A1 (en) 2005-07-14 2005-07-14 Methods for treating prostate cancer
US11/180,667 2005-07-14

Publications (2)

Publication Number Publication Date
WO2007011434A2 WO2007011434A2 (fr) 2007-01-25
WO2007011434A3 true WO2007011434A3 (fr) 2008-01-10

Family

ID=37669296

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/010668 WO2007011434A2 (fr) 2005-07-14 2006-03-22 Procedes destines a prevenir et a traiter des cancers qui expriment l'axe gonadal pituitaire ophtalmique d'hormones et de recepteurs

Country Status (1)

Country Link
WO (1) WO2007011434A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2090322A1 (fr) 2008-02-18 2009-08-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Utilisation de ligands du récepteur de la FSH pour le diagnostic et le traitement du cancer
US8680055B2 (en) * 2009-06-03 2014-03-25 University Of Southern California Methods for decreasing steroidogenesis in prostate cancer cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6642274B1 (en) * 1999-09-09 2003-11-04 Gary W. Neal Methods and compositions for preventing and treating prostate disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6642274B1 (en) * 1999-09-09 2003-11-04 Gary W. Neal Methods and compositions for preventing and treating prostate disorders

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ALLEN ET AL.: "Combined treatment with ketoconazole and luteinising hormone releasing hormone analogue: a novel approach to resistant progressive prostatic cancer", BRITISH MEDICAL JOURNAL, vol. 287, December 1983 (1983-12-01), pages 1766 *
BOLLA ET AL.: "Improved survival in patients with locally advanced prostate cancer treated with radiotherapy and goserelin", N. ENGL. J. MED., vol. 337, no. 5, July 1997 (1997-07-01), pages 295 - 300 *
COOK ET AL.: "Development of GnRH antagonists for prostate cancer: new approaches to treatment", THE ONCOLOGIST, vol. 5, April 2000 (2000-04-01), pages 162 - 168 *
DAWSON ET AL.: "A pilot trial of chemohormonal therapy for metastatic prostate carcinoma", CANCER, vol. 69, no. 1, January 1992 (1992-01-01), pages 213 - 218, XP055002314 *
FISHER ET AL.: "Abarelix Depot (A-D) monotherapy reduces PSA levels comparable to leuprolide acetate (L) plus bicalutamide (B): results of multicenter trial of rising PSA, advanced (D1/D2), neoadjuvant hormonal therapy (NHT), and intermittant hormonal therapy (IHT)....", PROC. AM. SOC. CLIN. ONCOL., vol. 20, 2001 *
UTRIANEN ET AL.: "Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R", J. OF ENDOCRINOLOGY, vol. 188, 2006, pages 305 - 310 *

Also Published As

Publication number Publication date
WO2007011434A2 (fr) 2007-01-25

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