[go: up one dir, main page]

WO2007011698A3 - Conjugues d'anticorps humanises et procedes correspondants, essais biologiques, reactifs et trousses - Google Patents

Conjugues d'anticorps humanises et procedes correspondants, essais biologiques, reactifs et trousses Download PDF

Info

Publication number
WO2007011698A3
WO2007011698A3 PCT/US2006/027312 US2006027312W WO2007011698A3 WO 2007011698 A3 WO2007011698 A3 WO 2007011698A3 US 2006027312 W US2006027312 W US 2006027312W WO 2007011698 A3 WO2007011698 A3 WO 2007011698A3
Authority
WO
WIPO (PCT)
Prior art keywords
humanized antibody
kits
reagents
antibody conjugates
related methods
Prior art date
Application number
PCT/US2006/027312
Other languages
English (en)
Other versions
WO2007011698A2 (fr
Inventor
Linda-Marie Anderson-Mauser
Mary Margaret Foltz
Robert John Dwyer
Original Assignee
Bayer Healthcare Llc
Linda-Marie Anderson-Mauser
Mary Margaret Foltz
Robert John Dwyer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc, Linda-Marie Anderson-Mauser, Mary Margaret Foltz, Robert John Dwyer filed Critical Bayer Healthcare Llc
Priority to EP06787249A priority Critical patent/EP1922412A4/fr
Publication of WO2007011698A2 publication Critical patent/WO2007011698A2/fr
Publication of WO2007011698A3 publication Critical patent/WO2007011698A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne des conjugués d'anticorps dérivés synthétiquement et par voie recombinante et les procédés correspondants, de dosages diagnostics, réactifs et trousses. Dans un mode de réalisation, l'invention concerne des conjugués d'anticorps humanisés contenant un fragment d'immunoglobuline humain qui est lié par un groupe fonctionnel de réticulation à un fragment d'anticorps non-humain (par ex., un fragment d'anticorps monoclonal non-humain) contenant une séquence d'acide aminé à liaison d'antigène.
PCT/US2006/027312 2005-07-15 2006-07-14 Conjugues d'anticorps humanises et procedes correspondants, essais biologiques, reactifs et trousses WO2007011698A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06787249A EP1922412A4 (fr) 2005-07-15 2006-07-14 Conjugues d'anticorps humanises et procedes correspondants, essais biologiques, reactifs et trousses

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69961805P 2005-07-15 2005-07-15
US60/699,618 2005-07-15
US70836105P 2005-08-31 2005-08-31
US60/708,361 2005-08-31

Publications (2)

Publication Number Publication Date
WO2007011698A2 WO2007011698A2 (fr) 2007-01-25
WO2007011698A3 true WO2007011698A3 (fr) 2007-06-28

Family

ID=37669378

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/027312 WO2007011698A2 (fr) 2005-07-15 2006-07-14 Conjugues d'anticorps humanises et procedes correspondants, essais biologiques, reactifs et trousses

Country Status (2)

Country Link
EP (1) EP1922412A4 (fr)
WO (1) WO2007011698A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7858752B2 (en) * 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
US20100143376A1 (en) * 2007-03-06 2010-06-10 Ribovax Biotechnologies S.A. Antibodies Specific for Rubella Virus
CN103383393B (zh) * 2013-06-28 2015-11-25 英科隆生物技术（杭州）有限公司 一种替代病人阳性血液的质控品
CN108445224A (zh) * 2018-02-26 2018-08-24 王贤俊 一种心型脂肪酸结合蛋白抗体片段复合胶乳颗粒及其制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929543A (en) * 1987-05-14 1990-05-29 Boehringer Mannheim Gmbh Process for the determination of an antibody in human body fluids
US5614367A (en) * 1989-01-10 1997-03-25 Boehringer Mannheim Gmbh Diagnostic test using chimeric antibodies
US6015662A (en) * 1996-01-23 2000-01-18 Abbott Laboratories Reagents for use as calibrators and controls
US6207815B1 (en) * 1988-10-19 2001-03-27 The Dow Chemical Company Family of high affinity, modified antibodies for cancer treatment
US6303755B1 (en) * 1996-07-11 2001-10-16 Medarex, Inc. Therapeutic multispecific compounds comprised of anti-FCA receptor antibodies
US6630292B2 (en) * 2000-04-25 2003-10-07 Fuji Photo Film B.V. Method for producing a silver halide photographic emulsion
US6849259B2 (en) * 2000-06-16 2005-02-01 Symphogen A/S Polyclonal antibody composition for treating allergy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681566A (en) * 1988-10-24 1997-10-28 3I Research Exploitation Limited Antibody conjugates with two or more covalently linked FC regions

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929543A (en) * 1987-05-14 1990-05-29 Boehringer Mannheim Gmbh Process for the determination of an antibody in human body fluids
US6207815B1 (en) * 1988-10-19 2001-03-27 The Dow Chemical Company Family of high affinity, modified antibodies for cancer treatment
US5614367A (en) * 1989-01-10 1997-03-25 Boehringer Mannheim Gmbh Diagnostic test using chimeric antibodies
US6015662A (en) * 1996-01-23 2000-01-18 Abbott Laboratories Reagents for use as calibrators and controls
US6303755B1 (en) * 1996-07-11 2001-10-16 Medarex, Inc. Therapeutic multispecific compounds comprised of anti-FCA receptor antibodies
US6630292B2 (en) * 2000-04-25 2003-10-07 Fuji Photo Film B.V. Method for producing a silver halide photographic emulsion
US6849259B2 (en) * 2000-06-16 2005-02-01 Symphogen A/S Polyclonal antibody composition for treating allergy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1922412A4 *

Also Published As

Publication number Publication date
EP1922412A4 (fr) 2009-07-15
EP1922412A2 (fr) 2008-05-21
WO2007011698A2 (fr) 2007-01-25

Similar Documents

Publication Publication Date Title
HRP20191462T1 (hr) Antitijela usmjerena protiv her-3 i njihove uporabe
EA201100527A1 (ru) Биологические продукты
WO2006104978A3 (fr) Anticorps dirigés contre les antigènes majeurs de la ténascine
IN2012DN02535A (fr)
WO2008101177A3 (fr) Anticorps ige contre des anticorps monoclonaux thérapeutiques igg chimériques ou humanisés en tant que test de criblage pour l'anaphylaxie
WO2006031653A3 (fr) Anticorps anti-5t4 humanises et conjugues anticorps anti-5t4/calicheamicine
WO2006130458A3 (fr) Anticorps diriges contre cd20 et leurs utilisations
WO2006071441A3 (fr) Anticorps dirigés contre la gpnmb et leurs utilisations
EA201100231A1 (ru) Диагностический анализ на основе антител
IL186948A0 (en) Monoclonal antibodies and methods for their use in the detection of cervical disease
WO2005016111A3 (fr) Anticorps diriges vers l'hormone parathyroide et leurs utilisations
WO2006113643A3 (fr) Anticorps monoclonaux entierement humains a affinite elevee d'interleukine-8 et epitopes destines a ces anticorps
WO2007035633A3 (fr) Techniques et procedes de criblage
WO2009010539A3 (fr) Recepteur de l'interleukine-6 (il-6) derive de macaca fascicularis
WO2006094192A3 (fr) Anticorps humanises l243
WO2006086208A3 (fr) Dosage immunologique de 5-fluoro-uracil
WO2006061723A3 (fr) Anticorps monoclonaux humains diriges contre la proteine m2 de la grippe, et methodes de production et d'utilisation desdits anticorps
UA94576C2 (ru) Выделенное антитело, которое связывается с igf-1r, композиция, которая его содержит, и способы, которые касаются антител
WO2006039258A3 (fr) Anticorps diriges contre la parathormone
EP3300739A3 (fr) Anticorps et molécules correspondantes se liant aux protéines 161p2f10b
MX2008002161A (es) Anticuerpos quimericos con regiones de primate del nuevo mundo.
WO2007001895A3 (fr) Anticorps monoclonaux, lignees cellulaires d'hybridome, procedes et trousses pour detecter la phytase
WO2008143697A3 (fr) Anticorps a selectivite de proteine a
WO2008140570A3 (fr) Anticorps à sélectivité de protéine a
WO2008009960A3 (fr) Anticorps diriges contre la testosterone

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2006787249

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE