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WO2007015739A3 - Revetements pea-tempo/pea-bz permettant une administration controlee de medicaments a partir de dispositifs medicaux implantables - Google Patents

Revetements pea-tempo/pea-bz permettant une administration controlee de medicaments a partir de dispositifs medicaux implantables Download PDF

Info

Publication number
WO2007015739A3
WO2007015739A3 PCT/US2006/027282 US2006027282W WO2007015739A3 WO 2007015739 A3 WO2007015739 A3 WO 2007015739A3 US 2006027282 W US2006027282 W US 2006027282W WO 2007015739 A3 WO2007015739 A3 WO 2007015739A3
Authority
WO
WIPO (PCT)
Prior art keywords
pea
tempo
medical devices
implantable medical
coatings
Prior art date
Application number
PCT/US2006/027282
Other languages
English (en)
Other versions
WO2007015739A2 (fr
Inventor
Jessica Renee Desnoyer
Lothar Walter Kleiner
Original Assignee
Advanced Cardiovascular System
Jessica Renee Desnoyer
Lothar Walter Kleiner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Cardiovascular System, Jessica Renee Desnoyer, Lothar Walter Kleiner filed Critical Advanced Cardiovascular System
Publication of WO2007015739A2 publication Critical patent/WO2007015739A2/fr
Publication of WO2007015739A3 publication Critical patent/WO2007015739A3/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/08Coatings comprising two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne un revêtement PEA-TEMPO/PEA-BZ pour dispositifs médicaux implantables, ledit revêtement étant utilisé dans l'administration contrôlée d'agents bioactifs dans le corps d'un patient.
PCT/US2006/027282 2005-07-29 2006-07-13 Revetements pea-tempo/pea-bz permettant une administration controlee de medicaments a partir de dispositifs medicaux implantables WO2007015739A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/192,624 2005-07-29
US11/192,624 US8377462B2 (en) 2005-07-29 2005-07-29 PEA-TEMPO/PEA-BZ coatings for controlled delivery of drug from implantable medical devices

Publications (2)

Publication Number Publication Date
WO2007015739A2 WO2007015739A2 (fr) 2007-02-08
WO2007015739A3 true WO2007015739A3 (fr) 2008-03-20

Family

ID=37694591

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/027282 WO2007015739A2 (fr) 2005-07-29 2006-07-13 Revetements pea-tempo/pea-bz permettant une administration controlee de medicaments a partir de dispositifs medicaux implantables

Country Status (2)

Country Link
US (1) US8377462B2 (fr)
WO (1) WO2007015739A2 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8017074B2 (en) 2004-01-07 2011-09-13 Noxilizer, Inc. Sterilization system and device
AU2005204360B2 (en) 2004-01-07 2011-03-31 Noxilizer, Inc. Sterilization system and device
WO2007011708A2 (fr) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent a revetement polymere renfermant de la rapamycine amorphe
US20070135909A1 (en) * 2005-12-08 2007-06-14 Desnoyer Jessica R Adhesion polymers to improve stent retention
US8293318B1 (en) 2006-08-29 2012-10-23 Abbott Cardiovascular Systems Inc. Methods for modulating the release rate of a drug-coated stent
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
CN101711137B (zh) 2007-01-08 2014-10-22 米歇尔技术公司 具有可生物降解层的支架
WO2008150974A1 (fr) * 2007-06-01 2008-12-11 Med-El Elektromedizinische Geraete Gmbh Revêtement souple biodégradable pour dispositifs médicaux implantables
US20090041845A1 (en) * 2007-08-08 2009-02-12 Lothar Walter Kleiner Implantable medical devices having thin absorbable coatings
US8271101B2 (en) * 2007-08-29 2012-09-18 Advanced Bionics Modular drug delivery system for minimizing trauma during and after insertion of a cochlear lead
US8190271B2 (en) 2007-08-29 2012-05-29 Advanced Bionics, Llc Minimizing trauma during and after insertion of a cochlear lead
EP3360586B1 (fr) 2008-04-17 2024-03-06 Micell Technologies, Inc. Stents à couches bioabsorbables
AU2009256310B2 (en) * 2008-06-03 2012-05-03 Med-El Elektromedizinische Geraete Gmbh Conductive coating of implants with inductive link
US8562669B2 (en) * 2008-06-26 2013-10-22 Abbott Cardiovascular Systems Inc. Methods of application of coatings composed of hydrophobic, high glass transition polymers with tunable drug release rates
US9486431B2 (en) 2008-07-17 2016-11-08 Micell Technologies, Inc. Drug delivery medical device
EP2358427B1 (fr) * 2008-10-08 2014-01-15 Med-El Elektromedizinische Geräte GmbH Protection d un tissu cochléaire du trauma d une électrode
JP5694964B2 (ja) 2009-02-23 2015-04-01 ノクシライザー, インコーポレイテッドNoxilizer, Incorporated ガス滅菌装置及びガス滅菌方法
WO2010120552A2 (fr) 2009-04-01 2010-10-21 Micell Technologies, Inc. Endoprothèses enduites
EP2453834A4 (fr) 2009-07-16 2014-04-16 Micell Technologies Inc Dispositif médical distributeur de médicament
WO2011097103A1 (fr) 2010-02-02 2011-08-11 Micell Technologies, Inc. Endoprothèse et système de pose d'endoprothèse avec une capacité améliorée de pose
CA2797110C (fr) 2010-04-22 2020-07-21 Micell Technologies, Inc. Endoprotheses et autres dispositifs ayant un revetement de matrice extracellulaire
US20130172853A1 (en) 2010-07-16 2013-07-04 Micell Technologies, Inc. Drug delivery medical device
US10117972B2 (en) 2011-07-15 2018-11-06 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
CN105307597A (zh) 2013-03-12 2016-02-03 脉胜医疗技术公司 可生物吸收的生物医学植入物
AU2014265460B2 (en) 2013-05-15 2018-10-18 Micell Technologies, Inc. Bioabsorbable biomedical implants
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
MX2019009931A (es) 2017-02-27 2020-07-14 Third Pole Inc Sistemas y metodos para generacion ambulatoria de oxido nitrico.
US11479464B2 (en) 2019-05-15 2022-10-25 Third Pole, Inc. Systems and methods for generating nitric oxide
US11045620B2 (en) 2019-05-15 2021-06-29 Third Pole, Inc. Electrodes for nitric oxide generation
US20230001119A1 (en) * 2019-11-01 2023-01-05 Third Pole, Inc. Systems and methods for increasing nitrogen monoxide concentration and removing nitrogen dioxide from a gas stream
EP4069069A4 (fr) 2020-01-11 2024-07-03 Third Pole, Inc. Systèmes et procédés de génération d'oxyde nitrique avec régulation de l'humidité
WO2021258025A1 (fr) 2020-06-18 2021-12-23 Third Pole, Inc. Systèmes et procédés de prévention et de traitement d'infections avec de l'oxyde nitrique
WO2023049873A1 (fr) 2021-09-23 2023-03-30 Third Pole, Inc. Systèmes et procédés destinés à fournir de l'oxyde nitrique

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020015720A1 (en) * 2000-01-11 2002-02-07 Ramaz Katsarava Polymer blends as biodegradable matrices for preparing biocomposites
US6503538B1 (en) * 2000-08-30 2003-01-07 Cornell Research Foundation, Inc. Elastomeric functional biodegradable copolyester amides and copolyester urethanes
WO2006041676A1 (fr) * 2004-10-06 2006-04-20 Advanced Cardiovascular Systems, Inc. Melanges de polymeres de poly(ester amide)
WO2007018886A2 (fr) * 2005-07-20 2007-02-15 Advanced Cardiovascular Systems, Inc. Procede de fabrication de dispositif medical implantable liberant un agent bioactif

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304767A (en) 1980-05-15 1981-12-08 Sri International Polymers of di- (and higher functionality) ketene acetals and polyols
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
HU222501B1 (hu) 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
US5824048A (en) * 1993-04-26 1998-10-20 Medtronic, Inc. Method for delivering a therapeutic substance to a body lumen
GB2281161B (en) 1993-08-04 1997-05-28 Fulcrum Communications Limited Optical data communications networks
US7758881B2 (en) * 2004-06-30 2010-07-20 Advanced Cardiovascular Systems, Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
CA2513443A1 (fr) * 2003-02-26 2004-09-10 Medivas, Llc Endoprotheses vasculaires bioactives et leur mode d'emploi
WO2004112864A2 (fr) * 2003-06-19 2004-12-29 Vascular Therapies Llc Dispositifs medicaux et methodes de regulation de la reponse tissulaire aux dispositifs d'obturation vasculaire
US7128742B2 (en) * 2003-07-08 2006-10-31 Olympus Corporation Electric operation apparatus and control method thereof
US7056591B1 (en) 2003-07-30 2006-06-06 Advanced Cardiovascular Systems, Inc. Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
US8192752B2 (en) 2003-11-21 2012-06-05 Advanced Cardiovascular Systems, Inc. Coatings for implantable devices including biologically erodable polyesters and methods for fabricating the same
US7220816B2 (en) 2003-12-16 2007-05-22 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same
US7435788B2 (en) 2003-12-19 2008-10-14 Advanced Cardiovascular Systems, Inc. Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
US8685431B2 (en) 2004-03-16 2014-04-01 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on copolymers having ester bonds and methods for fabricating the same
US7820732B2 (en) 2004-04-30 2010-10-26 Advanced Cardiovascular Systems, Inc. Methods for modulating thermal and mechanical properties of coatings on implantable devices
US20050265960A1 (en) 2004-05-26 2005-12-01 Pacetti Stephen D Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same
US20050271700A1 (en) 2004-06-03 2005-12-08 Desnoyer Jessica R Poly(ester amide) coating composition for implantable devices
US20060089485A1 (en) 2004-10-27 2006-04-27 Desnoyer Jessica R End-capped poly(ester amide) copolymers
US7390497B2 (en) 2004-10-29 2008-06-24 Advanced Cardiovascular Systems, Inc. Poly(ester amide) filler blends for modulation of coating properties
US8609123B2 (en) * 2004-11-29 2013-12-17 Advanced Cardiovascular Systems, Inc. Derivatized poly(ester amide) as a biobeneficial coating
US7632307B2 (en) * 2004-12-16 2009-12-15 Advanced Cardiovascular Systems, Inc. Abluminal, multilayer coating constructs for drug-delivery stents
US7419504B2 (en) 2004-12-27 2008-09-02 Advanced Cardiovascular Systems, Inc. Poly(ester amide) block copolymers
US8007775B2 (en) 2004-12-30 2011-08-30 Advanced Cardiovascular Systems, Inc. Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
US7202325B2 (en) 2005-01-14 2007-04-10 Advanced Cardiovascular Systems, Inc. Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020015720A1 (en) * 2000-01-11 2002-02-07 Ramaz Katsarava Polymer blends as biodegradable matrices for preparing biocomposites
US6503538B1 (en) * 2000-08-30 2003-01-07 Cornell Research Foundation, Inc. Elastomeric functional biodegradable copolyester amides and copolyester urethanes
WO2006041676A1 (fr) * 2004-10-06 2006-04-20 Advanced Cardiovascular Systems, Inc. Melanges de polymeres de poly(ester amide)
WO2007018886A2 (fr) * 2005-07-20 2007-02-15 Advanced Cardiovascular Systems, Inc. Procede de fabrication de dispositif medical implantable liberant un agent bioactif

Also Published As

Publication number Publication date
US20070026041A1 (en) 2007-02-01
US8377462B2 (en) 2013-02-19
WO2007015739A2 (fr) 2007-02-08

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