WO2007019119A3 - Rna complexes methods of their production and sensors and analytical methods involving same - Google Patents
Rna complexes methods of their production and sensors and analytical methods involving same Download PDFInfo
- Publication number
- WO2007019119A3 WO2007019119A3 PCT/US2006/029810 US2006029810W WO2007019119A3 WO 2007019119 A3 WO2007019119 A3 WO 2007019119A3 US 2006029810 W US2006029810 W US 2006029810W WO 2007019119 A3 WO2007019119 A3 WO 2007019119A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- binding sites
- rna
- methods
- sensors
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The invention includes RNA complexes comprising at least three monomeric units of an RNA molecule, each monomeric unit comprising an RNA polymer having first and second helical domains that have respective first and second binding sites, wherein the first binding sites are adapted to binding to one another and are not adapted to bind to the second binding sites, and the second binding sites are adapted to binding to one another and are not adapted to bind to the first binding sites; such that the at least three monomeric units are adapted to self-assemble by forming pairs of cognate interactions and so as to form the RNA complex in a circular closed complex. The invention also includes derivatives of these complexes including aptamers, and analytical methods and devices using same.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70504105P | 2005-08-03 | 2005-08-03 | |
US11/196,003 US7553945B2 (en) | 2005-08-03 | 2005-08-03 | RNA complexes and methods of their production |
US11/196,003 | 2005-08-03 | ||
US60/705,041 | 2005-08-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007019119A2 WO2007019119A2 (en) | 2007-02-15 |
WO2007019119A3 true WO2007019119A3 (en) | 2008-01-17 |
Family
ID=37727856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/029810 WO2007019119A2 (en) | 2005-08-03 | 2006-08-01 | Rna complexes methods of their production and sensors and analytical methods involving same |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007019119A2 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030065155A1 (en) * | 2000-03-06 | 2003-04-03 | Nassim Usman | Nucleic acid sensor molecules |
US6866819B1 (en) * | 2001-11-13 | 2005-03-15 | Raytheon Company | Sensor for detecting small concentrations of a target matter |
-
2006
- 2006-08-01 WO PCT/US2006/029810 patent/WO2007019119A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030065155A1 (en) * | 2000-03-06 | 2003-04-03 | Nassim Usman | Nucleic acid sensor molecules |
US6866819B1 (en) * | 2001-11-13 | 2005-03-15 | Raytheon Company | Sensor for detecting small concentrations of a target matter |
Non-Patent Citations (3)
Title |
---|
JAEGER ET AL.: "Tecto-RNA: One-Dimensional Self-Assembly through Tertiary Interactions", ANGEW. CHEM. INT. ED., vol. 39, no. 14, July 2000 (2000-07-01), pages 2521 - 2524 * |
SAYER ET AL.: "Structural characterization of a 20F-RNA aptamer that binds a HIV-1 SU glycoprotein, gp120", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 293, no. 3, May 2002 (2002-05-01), pages 924 - 931, XP002363739, DOI: doi:10.1016/S0006-291X(02)00308-X * |
SHU ET AL.: "Bottom-up Assembly of RNA Arrays and Superstructures as Potential Parts in Nanotechnology", NANO LETTERS, vol. 4, no. 9, August 2004 (2004-08-01), Retrieved from the Internet <URL:http://www.pubs.acs.org/cgi-bin/article.cgi/nalefd/2004/4/i09/pdf/nl0494497.pdf> * |
Also Published As
Publication number | Publication date |
---|---|
WO2007019119A2 (en) | 2007-02-15 |
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