WO2007038650A3 - Hyperspectral visible absorption imaging of molecular probes and dyes in biomaterials - Google Patents
Hyperspectral visible absorption imaging of molecular probes and dyes in biomaterials Download PDFInfo
- Publication number
- WO2007038650A3 WO2007038650A3 PCT/US2006/037780 US2006037780W WO2007038650A3 WO 2007038650 A3 WO2007038650 A3 WO 2007038650A3 US 2006037780 W US2006037780 W US 2006037780W WO 2007038650 A3 WO2007038650 A3 WO 2007038650A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sample
- platform
- optical lens
- transmission image
- mode
- Prior art date
Links
- 238000010521 absorption reaction Methods 0.000 title abstract 4
- 239000012620 biological material Substances 0.000 title 1
- 239000000975 dye Substances 0.000 title 1
- 238000003384 imaging method Methods 0.000 title 1
- 239000003068 molecular probe Substances 0.000 title 1
- 230000005540 biological transmission Effects 0.000 abstract 4
- 230000003287 optical effect Effects 0.000 abstract 4
- 239000011358 absorbing material Substances 0.000 abstract 1
- 239000000835 fiber Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003595 spectral effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Microscoopes, Condenser (AREA)
Abstract
A system and method for obtaining hyperspectral visible absorption images. The system includes a light source which illuminates a sample containing light absorbing material, a platform, an optical lens, a detector. The platform has a section for placement of the sample and a section devoid of sample. The transmitted photons produced by the sample and collected by the optical lens are separated into a plurality of wavelength bands using a filter or a fiber array spectral translator coupled to a spectrometer. The system includes a programmable code for operating in a sample mode or background mode and calculating an absorption image. In the background mode, the platform motion is controlled so the optical lens collects transmitted photons from the portion of the platform devoid of sample to generate a background transmission image. In the sample mode, the platform motion is controlled so the optical lens collects transmitted photons from the sample to generate a sample transmission image. The sample transmission image and the background transmission image are used to generate a photon absorption image of the sample.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06825187A EP1929277A2 (en) | 2005-09-26 | 2006-09-26 | Hyperspectral visible absorption imaging of molecular probes and dyes in biomaterials |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72053105P | 2005-09-26 | 2005-09-26 | |
| US60/720,531 | 2005-09-26 | ||
| US77879406P | 2006-03-03 | 2006-03-03 | |
| US60/778,794 | 2006-03-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2007038650A2 WO2007038650A2 (en) | 2007-04-05 |
| WO2007038650A3 true WO2007038650A3 (en) | 2008-11-27 |
Family
ID=37900448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2006/037780 WO2007038650A2 (en) | 2005-09-26 | 2006-09-26 | Hyperspectral visible absorption imaging of molecular probes and dyes in biomaterials |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP1929277A2 (en) |
| WO (1) | WO2007038650A2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7554659B2 (en) | 2004-06-30 | 2009-06-30 | Chemimage Corporation | Hyperspectral visible absorption imaging of molecular probes and dyes in biomaterials |
| KR100920749B1 (en) | 2007-10-02 | 2009-10-07 | 재단법인서울대학교산학협력재단 | A quantitative method for cellular assays based on hyperspectral imaging system |
| CN105028379B (en) * | 2015-06-24 | 2017-12-05 | 赵阳 | The automatic weeder of solar energy cumulative spectrum |
| US9645291B1 (en) * | 2016-04-18 | 2017-05-09 | Ii-Vi Incorporated | Voltage-tunable optical filters for instrumentation applications |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4948974A (en) * | 1984-06-25 | 1990-08-14 | Nelson Robert S | High resolution imaging apparatus and method for approximating scattering effects |
-
2006
- 2006-09-26 WO PCT/US2006/037780 patent/WO2007038650A2/en active Search and Examination
- 2006-09-26 EP EP06825187A patent/EP1929277A2/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4948974A (en) * | 1984-06-25 | 1990-08-14 | Nelson Robert S | High resolution imaging apparatus and method for approximating scattering effects |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1929277A2 (en) | 2008-06-11 |
| WO2007038650A2 (en) | 2007-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
| DPE2 | Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101) | ||
| WWE | Wipo information: entry into national phase |
Ref document number: 2006825187 Country of ref document: EP |
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| NENP | Non-entry into the national phase |
Ref country code: DE |
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| DPE2 | Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101) |