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WO2008030818A3 - Nouvelles compositions de liposomes - Google Patents

Nouvelles compositions de liposomes Download PDF

Info

Publication number
WO2008030818A3
WO2008030818A3 PCT/US2007/077548 US2007077548W WO2008030818A3 WO 2008030818 A3 WO2008030818 A3 WO 2008030818A3 US 2007077548 W US2007077548 W US 2007077548W WO 2008030818 A3 WO2008030818 A3 WO 2008030818A3
Authority
WO
WIPO (PCT)
Prior art keywords
liposome compositions
novel liposome
containing compositions
lipid
targeted liposomes
Prior art date
Application number
PCT/US2007/077548
Other languages
English (en)
Other versions
WO2008030818A2 (fr
Inventor
Yusuke Miyajima
Kazushi Okada
Naoyuki Morisaki
Original Assignee
Mebiopharm Co Ltd
Yusuke Miyajima
Kazushi Okada
Naoyuki Morisaki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mebiopharm Co Ltd, Yusuke Miyajima, Kazushi Okada, Naoyuki Morisaki filed Critical Mebiopharm Co Ltd
Publication of WO2008030818A2 publication Critical patent/WO2008030818A2/fr
Publication of WO2008030818A3 publication Critical patent/WO2008030818A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cette invention concerne des compositions contenant des lipides, dont des liposomes ciblés encapsulant du méthotrexate, et des préparations pharmaceutiques de ces compositions, ainsi que des méthodes de fabrication et d'utilisation des compositions contenant des lipides, y compris l'utilisation de liposomes ciblés pour le traitement du cancer, de la polyarthrite rhumatoïde et d'autres pathologies.
PCT/US2007/077548 2006-09-05 2007-09-04 Nouvelles compositions de liposomes WO2008030818A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84246706P 2006-09-05 2006-09-05
US60/842,467 2006-09-05
US90527007P 2007-03-05 2007-03-05
US60/905,270 2007-03-05

Publications (2)

Publication Number Publication Date
WO2008030818A2 WO2008030818A2 (fr) 2008-03-13
WO2008030818A3 true WO2008030818A3 (fr) 2008-06-05

Family

ID=39157979

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/077548 WO2008030818A2 (fr) 2006-09-05 2007-09-04 Nouvelles compositions de liposomes

Country Status (1)

Country Link
WO (1) WO2008030818A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829113B2 (en) 2005-03-10 2010-11-09 Mebiopharm Co., Ltd. Liposome compositions

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9770414B2 (en) * 2010-05-13 2017-09-26 Pacira Pharmaceuticals, Inc. Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent
EP2632553B1 (fr) 2010-10-28 2020-01-01 Pacira Pharmaceuticals, Inc. Formulation à libération prolongée d'un médicament anti-inflammatoire non-stéroïdien
WO2014008469A2 (fr) 2012-07-05 2014-01-09 Taiwan Liposome Company, Ltd. Méthodes de traitement de l'arthrite
ES2733061T3 (es) 2012-08-10 2019-11-27 Taiho Pharmaceutical Co Ltd Dispersión acuosa de liposomas encapsulantes de oxaliplatino estable y método para estabilización de la misma
WO2018031967A1 (fr) 2016-08-12 2018-02-15 L.E.A.F. Holdings Group Llc Antifolates de polyglutamates et leurs utilisations.
EA201990473A1 (ru) 2016-08-12 2019-07-31 Эл.И.Эй.Эф. ХОЛДИНГС ГРУП ЭлЭлСи Полиглутамированные антифолаты и их применение
WO2018094253A1 (fr) 2016-11-18 2018-05-24 Pacira Pharmaceuticals, Inc. Formulations de liposomes multivésiculaires à microparticules de complexe de méloxicam de zinc et leurs procédés de fabrication
CN115475142A (zh) * 2017-11-20 2022-12-16 平顶山学院 一种口服甲氨蝶呤脂质体及其制备方法
EP3749319A4 (fr) 2018-02-07 2022-06-22 L.E.A.F Holdings Group LLC Tétrahydrofolates alpha polyglutamés et leurs utilisations
US12220431B2 (en) 2018-02-07 2025-02-11 L.E.A.F. Holdings Group Llc Gamma polyglutamated antifolates and uses thereof
CN111954530A (zh) 2018-02-07 2020-11-17 L.E.A.F.控股集团公司 γ聚谷氨酸化培美曲塞及其用途
EP3749320A4 (fr) 2018-02-07 2022-03-09 L.E.A.F Holdings Group LLC Aminoptérine alpha-polyglutamatée et utilisations associées
WO2019157129A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Pralatrexate alpha-polyglutamaté et utilisations associées
CA3090381A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Lometrexol alpha-polyglutamate et utilisations associees
CA3090500A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Antifolates alpha-polyglutamates et utilisations associees
CA3090494A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Pemetrexed alpha-polyglutamate et utilisations associees
CA3090389A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Raltitrexed alpha-polyglutamate et utilisations associees
US12239734B2 (en) 2018-02-07 2025-03-04 L.E.A.F. Holdings Group Llc Gamma polyglutamated raltitrexed and uses thereof
CA3090509A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Methotrexate alpha-polyglutamate et utilisations associees
US12048766B2 (en) 2018-02-14 2024-07-30 L.E.A.F. Holdings Group Llc Gamma polyglutamated tetrahydrofolates and uses thereof
WO2019160734A1 (fr) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Lométrexol gamma polyglutamique et ses utilisations
US12350271B2 (en) 2018-02-14 2025-07-08 L.E.A.F. Holdings Group Llc Gamma polyglutamated aminopterin and uses thereof
JP7462950B2 (ja) 2018-02-14 2024-04-08 エル．イー．エー．エフ． ホールディングス グループ エルエルシー ガンマポリグルタミン酸化メトトレキセートおよびその使用
US12048767B2 (en) 2018-02-14 2024-07-30 L.E.A.F. Holdings Group Llc Gamma polyglutamated pralatrexate and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294191B1 (en) * 1996-10-15 2001-09-25 The Liposome Company, Inc. N-acyl phosphatidylethanolamine-mediated liposomal drug delivery

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294191B1 (en) * 1996-10-15 2001-09-25 The Liposome Company, Inc. N-acyl phosphatidylethanolamine-mediated liposomal drug delivery

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829113B2 (en) 2005-03-10 2010-11-09 Mebiopharm Co., Ltd. Liposome compositions
US8758810B2 (en) 2005-03-10 2014-06-24 Mebiopharm Co., Ltd. Liposome compositions

Also Published As

Publication number Publication date
WO2008030818A2 (fr) 2008-03-13

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