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WO2008037037A3 - Médicament anti-asthmatique - Google Patents

Médicament anti-asthmatique Download PDF

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Publication number
WO2008037037A3
WO2008037037A3 PCT/BG2007/000021 BG2007000021W WO2008037037A3 WO 2008037037 A3 WO2008037037 A3 WO 2008037037A3 BG 2007000021 W BG2007000021 W BG 2007000021W WO 2008037037 A3 WO2008037037 A3 WO 2008037037A3
Authority
WO
WIPO (PCT)
Prior art keywords
asthmatic
medicine
hydrochloricum
sulfuricum
sulfaguajacolicum
Prior art date
Application number
PCT/BG2007/000021
Other languages
English (en)
Other versions
WO2008037037A2 (fr
Inventor
Ivan Hristov
Original Assignee
Ivan Hristov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivan Hristov filed Critical Ivan Hristov
Publication of WO2008037037A2 publication Critical patent/WO2008037037A2/fr
Publication of WO2008037037A3 publication Critical patent/WO2008037037A3/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/48Ergoline derivatives, e.g. lysergic acid, ergotamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne un médicament anti-asthmatique qui peut être utilisé en médecine humaine pour traiter un asthme ou une bronchite asthmatique. Ce médicament contient coffeinum purum, ergotamintartarat, zincum sulfuricum, papaverinum hydrochloricum, atropinum sulfuricum, aminophyllinum, glaucinum hydrochloricum, kalium sulfaguajacolicum et chlorpyraminum, dans les proportions suivantes [en mg] : coffeinum purum 30,00 à 250,00; ergotamintartarat 0,25 à 2,00; zincum sulfuricum 10,00 à 400,00; papaverinum hydrochloricum 30,00 à 200,00; atropinum sulfuricum 0,25 à 1,00; aminophyllinum 40,00 à 250,00; glaucinum hydrochloricum 30,00 à 250,00; kalium sulfaguajacolicum 100,00 à 600,00; chlorpyraminum 30,00 à 200,00. Ce médicament est avantageux en ce qu'il permet de maîtriser les crises d'asthme les plus aigües en l'espace de 30-40 minutes, en ce qu'il empêche la réapparition d'une respiration asthmatique douloureuse et de crises asthmatiques résultantes sur une période de 10 à 20 ans, voire au-delà, c'est-à-dire que la maladie est traitée en pratique, en ce qu'il empêche les effets secondaires importants et les complications causés par les corticostéroïdes et en ce qu'il est très bien supporté et n'engendre pas de complications.
PCT/BG2007/000021 2006-09-26 2007-09-19 Médicament anti-asthmatique WO2008037037A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BG109687 2006-09-26
BG109687A BG109687A (bg) 2006-09-26 2006-09-26 Антиастматично лекарствено средство

Publications (2)

Publication Number Publication Date
WO2008037037A2 WO2008037037A2 (fr) 2008-04-03
WO2008037037A3 true WO2008037037A3 (fr) 2008-07-10

Family

ID=39060181

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BG2007/000021 WO2008037037A2 (fr) 2006-09-26 2007-09-19 Médicament anti-asthmatique

Country Status (2)

Country Link
BG (1) BG109687A (fr)
WO (1) WO2008037037A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113633710A (zh) * 2021-09-29 2021-11-12 浙江养和健康管理科技有限公司 一种治疗支气管炎、哮喘和肺气肿的中药组合物及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996031222A1 (fr) * 1994-03-23 1996-10-10 Ivan Dimitrov Hristov Preparation antiashtmatique
US20010010825A1 (en) * 1998-07-28 2001-08-02 Toshihiro Shimizu Rapidly disintegrable solid preparation
BG105687U (en) * 2001-07-10 2003-01-31 "Софарма" Ад Combined means for affecting the respiratory system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996031222A1 (fr) * 1994-03-23 1996-10-10 Ivan Dimitrov Hristov Preparation antiashtmatique
US20010010825A1 (en) * 1998-07-28 2001-08-02 Toshihiro Shimizu Rapidly disintegrable solid preparation
BG105687U (en) * 2001-07-10 2003-01-31 "Софарма" Ад Combined means for affecting the respiratory system

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EPODOC EUROPEAN PATENT OFFICE, THE HAGUE, NL; XP002478408 *
SZEMERE P A ET AL: "Consumption of antihistamines and antiasthmatics in Hungary during 1992-1996", INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, vol. 118, no. 2-4, February 1999 (1999-02-01), pages 335 - 337, XP009096574, ISSN: 1018-2438 *
WAN HUAN-YING ET AL: "Effect of theophylline and glucose injection in treating acute asthma", ZHONGGUO XINYAO YU LINCHUANG ZAZHI, vol. 23, no. 3, March 2004 (2004-03-01), pages 159 - 163, XP002470608, ISSN: 1007-7669 *

Also Published As

Publication number Publication date
WO2008037037A2 (fr) 2008-04-03
BG109687A (bg) 2008-03-31

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