WO2008116118A3 - Anticorps totalement humains de bactéries à gram positif - Google Patents
Anticorps totalement humains de bactéries à gram positif Download PDFInfo
- Publication number
- WO2008116118A3 WO2008116118A3 PCT/US2008/057750 US2008057750W WO2008116118A3 WO 2008116118 A3 WO2008116118 A3 WO 2008116118A3 US 2008057750 W US2008057750 W US 2008057750W WO 2008116118 A3 WO2008116118 A3 WO 2008116118A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fully human
- human antibodies
- positive bacteria
- gram positive
- aureus
- Prior art date
Links
- 241000192125 Firmicutes Species 0.000 title 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 abstract 1
- 241000191967 Staphylococcus aureus Species 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 229960003085 meticillin Drugs 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention concerne, dans certains modes de réalisation, des anticorps totalement humains qui se lient à Staphylococcus aureus et véhiculent une tuerie υpsυnυphagocytique en présence de cellules polymorphes nucléaires humaines et d'un complément humain. Les anticorps sont utiles pour le traitement ou la prophylaxie de diverses infections provoquées par S. aureus, y compris MRSA (S. aureus résistant à la méthicilline).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89587807P | 2007-03-20 | 2007-03-20 | |
| US60/895,878 | 2007-03-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2008116118A2 WO2008116118A2 (fr) | 2008-09-25 |
| WO2008116118A3 true WO2008116118A3 (fr) | 2008-12-31 |
Family
ID=39766779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2008/057750 WO2008116118A2 (fr) | 2007-03-20 | 2008-03-20 | Anticorps totalement humains de bactéries à gram positif |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2008116118A2 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025010424A1 (fr) * | 2023-07-06 | 2025-01-09 | Vir Biotechnology, Inc. | Anticorps dirigés contre des antigènes de staphylococcus et leurs méthodes d'utilisation |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040052779A1 (en) * | 2001-12-21 | 2004-03-18 | Stinson Jeffrey R. | Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria |
-
2008
- 2008-03-20 WO PCT/US2008/057750 patent/WO2008116118A2/fr active Application Filing
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040052779A1 (en) * | 2001-12-21 | 2004-03-18 | Stinson Jeffrey R. | Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008116118A2 (fr) | 2008-09-25 |
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