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WO2008130590A3 - Biodegradable matrix materials - Google Patents

Biodegradable matrix materials Download PDF

Info

Publication number
WO2008130590A3
WO2008130590A3 PCT/US2008/004949 US2008004949W WO2008130590A3 WO 2008130590 A3 WO2008130590 A3 WO 2008130590A3 US 2008004949 W US2008004949 W US 2008004949W WO 2008130590 A3 WO2008130590 A3 WO 2008130590A3
Authority
WO
WIPO (PCT)
Prior art keywords
matrix materials
delivery
component
situ
biodegradable matrix
Prior art date
Application number
PCT/US2008/004949
Other languages
French (fr)
Other versions
WO2008130590A2 (en
Inventor
Dale G. Swan
Jr. William B. Knopke
Stephen J. Chudzik
Original Assignee
Surmodics, Inc.
Reed, Pamela, Jo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surmodics, Inc., Reed, Pamela, Jo filed Critical Surmodics, Inc.
Publication of WO2008130590A2 publication Critical patent/WO2008130590A2/en
Publication of WO2008130590A3 publication Critical patent/WO2008130590A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

The invention provides biodegradable degradable matrix materials. The matrix materials of the invention are useful in a variety of applications such as to make implantable medical devices (e.g., implants, coatings, in-situ formed matrices, stents, tubes, aneurysm coils, and the like), in-situ delivery (e.g., cell delivery or bioactive agent delivery), and as tissue sealants. In many embodiments, the matrix materials of the invention are formed by reacting: (a) a first component comprising an aminated natural degradable polysaccharide with (b) a second component comprising an amine-reactive compound.
PCT/US2008/004949 2007-04-19 2008-04-17 Biodegradable matrix materials WO2008130590A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92527507P 2007-04-19 2007-04-19
US60/925,275 2007-04-19

Publications (2)

Publication Number Publication Date
WO2008130590A2 WO2008130590A2 (en) 2008-10-30
WO2008130590A3 true WO2008130590A3 (en) 2009-11-05

Family

ID=39539661

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/004949 WO2008130590A2 (en) 2007-04-19 2008-04-17 Biodegradable matrix materials

Country Status (1)

Country Link
WO (1) WO2008130590A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102167812B (en) * 2010-02-26 2016-04-20 北京科美森医药研发有限公司 PEGylated cyclopamine analogue, and preparation method and application thereof

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009067A1 (en) * 1997-08-20 1999-02-25 Hercules Incorporated Amine modified polysaccharides
US20030129730A1 (en) * 2001-11-15 2003-07-10 Abdellatif Chenite Composition and method to homogeneously modify or cross-link chitosan under neutral conditions
WO2004073034A2 (en) * 2003-02-12 2004-08-26 University Of Maryland College Park Controlled electrochemical deposition of polysaccharides, films and hydrogel and materials formed therefrom
WO2005113034A1 (en) * 2004-05-12 2005-12-01 Surmodics, Inc. Natural biodegradable polysaccharides coatings for medical articles
WO2006029519A1 (en) * 2004-09-14 2006-03-23 Archer-Daniels-Midland Company Guanidinated polysaccharides, their use as absorbents and process for producing same
WO2007083870A1 (en) * 2006-01-19 2007-07-26 Seoul National University Of Technology Center For Industry Collaboration Chitosan or hyaluronic acid-poly(ethylene oxide)- and chitosan-hyaluronic acid-poly(ethylene oxide)-based hydrogel and manufacturing method therefor
WO2007127318A2 (en) * 2006-04-25 2007-11-08 Surmodics, Inc. Hydrophilic shape memory insertable medical articles
WO2008002482A2 (en) * 2006-06-23 2008-01-03 Surmodics, Inc. Hydrogel-based joint repair system and method
WO2009080220A1 (en) * 2007-12-21 2009-07-02 Sigea S.R.L. Polysaccharide derivatives of lipoic acid, their preparation, use as skin cosmetics and medical devices

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009067A1 (en) * 1997-08-20 1999-02-25 Hercules Incorporated Amine modified polysaccharides
US20030129730A1 (en) * 2001-11-15 2003-07-10 Abdellatif Chenite Composition and method to homogeneously modify or cross-link chitosan under neutral conditions
WO2004073034A2 (en) * 2003-02-12 2004-08-26 University Of Maryland College Park Controlled electrochemical deposition of polysaccharides, films and hydrogel and materials formed therefrom
WO2005113034A1 (en) * 2004-05-12 2005-12-01 Surmodics, Inc. Natural biodegradable polysaccharides coatings for medical articles
WO2006029519A1 (en) * 2004-09-14 2006-03-23 Archer-Daniels-Midland Company Guanidinated polysaccharides, their use as absorbents and process for producing same
WO2007083870A1 (en) * 2006-01-19 2007-07-26 Seoul National University Of Technology Center For Industry Collaboration Chitosan or hyaluronic acid-poly(ethylene oxide)- and chitosan-hyaluronic acid-poly(ethylene oxide)-based hydrogel and manufacturing method therefor
WO2007127318A2 (en) * 2006-04-25 2007-11-08 Surmodics, Inc. Hydrophilic shape memory insertable medical articles
WO2008002482A2 (en) * 2006-06-23 2008-01-03 Surmodics, Inc. Hydrogel-based joint repair system and method
WO2009080220A1 (en) * 2007-12-21 2009-07-02 Sigea S.R.L. Polysaccharide derivatives of lipoic acid, their preparation, use as skin cosmetics and medical devices

Also Published As

Publication number Publication date
WO2008130590A2 (en) 2008-10-30

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