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WO2009054361A1 - Hair growth promoter - Google Patents

Hair growth promoter Download PDF

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Publication number
WO2009054361A1
WO2009054361A1 PCT/JP2008/069004 JP2008069004W WO2009054361A1 WO 2009054361 A1 WO2009054361 A1 WO 2009054361A1 JP 2008069004 W JP2008069004 W JP 2008069004W WO 2009054361 A1 WO2009054361 A1 WO 2009054361A1
Authority
WO
WIPO (PCT)
Prior art keywords
hair growth
growth promoter
peptide compound
disclosed
seq
Prior art date
Application number
PCT/JP2008/069004
Other languages
French (fr)
Japanese (ja)
Inventor
Hideki Matsui
Kazuhito Tomizawa
Atsushi Fujimura
Original Assignee
National University Corporation Okayama University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University Corporation Okayama University filed Critical National University Corporation Okayama University
Priority to JP2009538209A priority Critical patent/JP5399913B2/en
Publication of WO2009054361A1 publication Critical patent/WO2009054361A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Disclosed is a hair growth promoter which can induce more efficient hair growth when applied externally, and which has little adverse side effects. Specifically disclosed is a hair growth promoter which comprises, as an active ingredient, a peptide compound containing 9 to 13 arginine residues and the amino acid sequence depicted in SEQ ID NO:1, wherein the peptide compound is a CaN/NFAT pathway-specific inhibitor having a cell membrane permeability.
PCT/JP2008/069004 2007-10-22 2008-10-21 Hair growth promoter WO2009054361A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009538209A JP5399913B2 (en) 2007-10-22 2008-10-21 Hair growth promoter

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007273889 2007-10-22
JP2007-273889 2007-10-22

Publications (1)

Publication Number Publication Date
WO2009054361A1 true WO2009054361A1 (en) 2009-04-30

Family

ID=40579466

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/069004 WO2009054361A1 (en) 2007-10-22 2008-10-21 Hair growth promoter

Country Status (2)

Country Link
JP (1) JP5399913B2 (en)
WO (1) WO2009054361A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010146622A1 (en) * 2009-06-15 2010-12-23 花王株式会社 Nfat signal inhibitor and calcineurin inhibitor
WO2013031833A1 (en) * 2011-08-31 2013-03-07 国立大学法人岡山大学 Skin introduction system and lightening agent combining cell introduction peptide and skin introduction accelerator

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003252898A (en) * 2002-02-28 2003-09-10 Hideki Matsui Membrane-permeable NFAT inhibitory peptide

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003252898A (en) * 2002-02-28 2003-09-10 Hideki Matsui Membrane-permeable NFAT inhibitory peptide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GAFTER-GVILI, A. ET AL.: "Cyclosporin A-induced hair growth in mice is associated with inhibition of calcineurin-dependent activation of NFAT in follicular keratinocytes", AM J PHYSIOL CELL PHYSIOL, vol. 284, no. 6, 2003, pages C1593 - C1603 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010146622A1 (en) * 2009-06-15 2010-12-23 花王株式会社 Nfat signal inhibitor and calcineurin inhibitor
US8470376B2 (en) 2009-06-15 2013-06-25 Kao Corporation NFAT signal inhibitor and calcineurin inhibitor
US8808758B2 (en) 2009-06-15 2014-08-19 Kao Corporation NFAT signal inhibitor and calcineurin inhibitor
WO2013031833A1 (en) * 2011-08-31 2013-03-07 国立大学法人岡山大学 Skin introduction system and lightening agent combining cell introduction peptide and skin introduction accelerator

Also Published As

Publication number Publication date
JPWO2009054361A1 (en) 2011-03-03
JP5399913B2 (en) 2014-01-29

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