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WO2009008001A3 - Inhalation device - Google Patents

Inhalation device Download PDF

Info

Publication number
WO2009008001A3
WO2009008001A3 PCT/IN2008/000277 IN2008000277W WO2009008001A3 WO 2009008001 A3 WO2009008001 A3 WO 2009008001A3 IN 2008000277 W IN2008000277 W IN 2008000277W WO 2009008001 A3 WO2009008001 A3 WO 2009008001A3
Authority
WO
WIPO (PCT)
Prior art keywords
inhalation device
inhalation
medicament
administration
patient
Prior art date
Application number
PCT/IN2008/000277
Other languages
French (fr)
Other versions
WO2009008001A2 (en
Inventor
Subhas Balaram Bhowmick
Prashant Kane
Ganesh Sangaiah
Satish Madhukar Gokhale
Ajay Nandgaonkar
Abhijit Takale
Simon James Smith
Samantha Anne Musgrave
Richard Francis Day
Lee Wood
Becky Lynn Pilditch
David Stuart Harris
Jonathan Hugh Wilkins
Duncan Aleck Bishop
Matthew David Allen
Original Assignee
Sun Pharma Advanced Res Co Ltd
Subhas Balaram Bhowmick
Prashant Kane
Ganesh Sangaiah
Satish Madhukar Gokhale
Ajay Nandgaonkar
Abhijit Takale
Simon James Smith
Samantha Anne Musgrave
Richard Francis Day
Lee Wood
Becky Lynn Pilditch
David Stuart Harris
Jonathan Hugh Wilkins
Duncan Aleck Bishop
Matthew David Allen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharma Advanced Res Co Ltd, Subhas Balaram Bhowmick, Prashant Kane, Ganesh Sangaiah, Satish Madhukar Gokhale, Ajay Nandgaonkar, Abhijit Takale, Simon James Smith, Samantha Anne Musgrave, Richard Francis Day, Lee Wood, Becky Lynn Pilditch, David Stuart Harris, Jonathan Hugh Wilkins, Duncan Aleck Bishop, Matthew David Allen filed Critical Sun Pharma Advanced Res Co Ltd
Priority to US12/598,241 priority Critical patent/US8499758B2/en
Priority to EP08826196.1A priority patent/EP2142239B1/en
Priority to CN2008800141765A priority patent/CN101980739B/en
Priority to ES08826196.1T priority patent/ES2637397T3/en
Priority to CA002683724A priority patent/CA2683724A1/en
Priority to JP2010505016A priority patent/JP5356367B2/en
Publication of WO2009008001A2 publication Critical patent/WO2009008001A2/en
Publication of WO2009008001A3 publication Critical patent/WO2009008001A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081—Locking means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/587—Lighting arrangements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to an inhalation-activatable device for administration of medicament in powder form to the respiratory system of a patient.
PCT/IN2008/000277 2007-04-30 2008-04-30 Inhalation device WO2009008001A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US12/598,241 US8499758B2 (en) 2007-04-30 2008-04-30 Inhalation device
EP08826196.1A EP2142239B1 (en) 2007-04-30 2008-04-30 Inhalation device
CN2008800141765A CN101980739B (en) 2007-04-30 2008-04-30 Inhalation device
ES08826196.1T ES2637397T3 (en) 2007-04-30 2008-04-30 Inhalation device
CA002683724A CA2683724A1 (en) 2007-04-30 2008-04-30 Inhalation device
JP2010505016A JP5356367B2 (en) 2007-04-30 2008-04-30 Inhaler

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN841/MUM/2007 2007-04-30
IN841MU2007 2007-04-30

Publications (2)

Publication Number Publication Date
WO2009008001A2 WO2009008001A2 (en) 2009-01-15
WO2009008001A3 true WO2009008001A3 (en) 2009-04-30

Family

ID=40229221

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2008/000277 WO2009008001A2 (en) 2007-04-30 2008-04-30 Inhalation device

Country Status (8)

Country Link
US (1) US8499758B2 (en)
EP (1) EP2142239B1 (en)
JP (1) JP5356367B2 (en)
CN (1) CN101980739B (en)
CA (1) CA2683724A1 (en)
ES (1) ES2637397T3 (en)
HU (1) HUE034380T2 (en)
WO (1) WO2009008001A2 (en)

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ES2543007T3 (en) 2004-08-23 2015-08-13 Mannkind Corporation Microparticles comprising diketopiperazine salts for drug administration
ES2640282T3 (en) 2005-09-14 2017-11-02 Mannkind Corporation Drug formulation method based on increasing the affinity of crystalline microparticle surfaces for active agents
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
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JP5570996B2 (en) 2007-12-14 2014-08-13 エアロデザインズ インコーポレイテッド Delivery of aerosolizable foodstuffs
CN106039494B (en) 2008-06-13 2019-12-24 曼金德公司 Dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN102065942B (en) 2008-06-20 2013-12-11 曼金德公司 Interactive device and method for real-time depiction of inhalation work
GB2461752B (en) * 2008-07-14 2013-04-17 Neo Inhalation Products Ltd Metered dose inhaler
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US8887722B2 (en) * 2008-09-26 2014-11-18 Oriel Therapeutics, Inc. Inhaler mechanisms with radially biased piercers and related methods
EP2346556B1 (en) 2008-09-26 2014-11-05 Oriel Therapeutics, Inc. Dry powder inhalers with dual piercing members and related devices and methods
EP2346557B9 (en) 2008-09-26 2016-09-28 Oriel Therapeutics, Inc. Inhalers with airway disks having discrete airway channels and related disks and methods
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Title
See also references of EP2142239A4 *

Also Published As

Publication number Publication date
CA2683724A1 (en) 2009-01-15
EP2142239B1 (en) 2017-06-07
JP2010525864A (en) 2010-07-29
CN101980739B (en) 2013-06-26
CN101980739A (en) 2011-02-23
US8499758B2 (en) 2013-08-06
ES2637397T3 (en) 2017-10-13
JP5356367B2 (en) 2013-12-04
EP2142239A2 (en) 2010-01-13
HUE034380T2 (en) 2018-02-28
US20100163042A1 (en) 2010-07-01
WO2009008001A2 (en) 2009-01-15
EP2142239A4 (en) 2014-12-24

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