WO2012030309A3 - Formulation d'un inhibiteur des canaux calciques - Google Patents
Formulation d'un inhibiteur des canaux calciques Download PDFInfo
- Publication number
- WO2012030309A3 WO2012030309A3 PCT/TR2011/000199 TR2011000199W WO2012030309A3 WO 2012030309 A3 WO2012030309 A3 WO 2012030309A3 TR 2011000199 W TR2011000199 W TR 2011000199W WO 2012030309 A3 WO2012030309 A3 WO 2012030309A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tiotropium
- calcium channel
- channel blocker
- formulation
- copd
- Prior art date
Links
- 229940127291 Calcium channel antagonist Drugs 0.000 title abstract 2
- 239000000480 calcium channel blocker Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title abstract 2
- 229940110309 tiotropium Drugs 0.000 title abstract 2
- 208000018569 Respiratory Tract disease Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne une formulation de poudre sèche, comprenant au moins un inhibiteur des canaux calciques et le tiotropium, qui a été développée pour être utilisée dans le traitement des maladies des voies respiratoires tel que l'asthme et la BPCO.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11767092.7A EP2611447A2 (fr) | 2010-09-01 | 2011-08-24 | Formulation comprenant le tiotropium et un inhibiteur des canaux calciques |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2010/07251A TR201007251A2 (tr) | 2010-09-01 | 2010-09-01 | Kalsiyum kanal blokörü formülasyonu. |
| TR2010/07251 | 2010-09-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2012030309A2 WO2012030309A2 (fr) | 2012-03-08 |
| WO2012030309A3 true WO2012030309A3 (fr) | 2012-08-09 |
Family
ID=44764205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/TR2011/000199 WO2012030309A2 (fr) | 2010-09-01 | 2011-08-24 | Formulation d'un inhibiteur des canaux calciques |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2611447A2 (fr) |
| TR (1) | TR201007251A2 (fr) |
| WO (1) | WO2012030309A2 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011041595A1 (fr) * | 2009-09-30 | 2011-04-07 | Microdose Therapeutx, Inc. | Procédés et compositions pour le traitement du phénomène de raynaud |
| JP6092015B2 (ja) * | 2013-06-19 | 2017-03-08 | 日本碍子株式会社 | 単結晶体の製造方法 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR890004691B1 (ko) * | 1985-07-02 | 1989-11-25 | 키 파마슈티칼스, 인코포레이티드 | 만성 폐색성 폐질환의 치료용 및 조성물 |
| US20020106332A1 (en) * | 2000-10-12 | 2002-08-08 | Michael Walz | Process for preparing powder formulations |
| US20020110529A1 (en) * | 2000-10-12 | 2002-08-15 | Karoline Bechtold-Peters | Inhalable powder containing tiotropium |
| US20030018019A1 (en) * | 2001-06-23 | 2003-01-23 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics |
| WO2003088944A1 (fr) * | 2002-04-13 | 2003-10-30 | Glaxo Group Limited | Composition de poudre seche a inhaler |
| WO2008152398A2 (fr) * | 2007-06-14 | 2008-12-18 | Cipla Limited | Formulations pour inhalation |
| US20090088408A1 (en) * | 2001-06-23 | 2009-04-02 | Meade Christopher J M | Pharmaceutical compositions on anticholinergics, corticosteroids and betamimetics |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001092267A2 (fr) | 2000-05-30 | 2001-12-06 | Ortho-Mcneil Pharmaceutical, Inc. | Medicaments a base de dihydropyridine, compositions et procedes associes |
-
2010
- 2010-09-01 TR TR2010/07251A patent/TR201007251A2/xx unknown
-
2011
- 2011-08-24 EP EP11767092.7A patent/EP2611447A2/fr not_active Withdrawn
- 2011-08-24 WO PCT/TR2011/000199 patent/WO2012030309A2/fr active Application Filing
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR890004691B1 (ko) * | 1985-07-02 | 1989-11-25 | 키 파마슈티칼스, 인코포레이티드 | 만성 폐색성 폐질환의 치료용 및 조성물 |
| US20020106332A1 (en) * | 2000-10-12 | 2002-08-08 | Michael Walz | Process for preparing powder formulations |
| US20020110529A1 (en) * | 2000-10-12 | 2002-08-15 | Karoline Bechtold-Peters | Inhalable powder containing tiotropium |
| US20030018019A1 (en) * | 2001-06-23 | 2003-01-23 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics |
| US20090088408A1 (en) * | 2001-06-23 | 2009-04-02 | Meade Christopher J M | Pharmaceutical compositions on anticholinergics, corticosteroids and betamimetics |
| WO2003088944A1 (fr) * | 2002-04-13 | 2003-10-30 | Glaxo Group Limited | Composition de poudre seche a inhaler |
| WO2008152398A2 (fr) * | 2007-06-14 | 2008-12-18 | Cipla Limited | Formulations pour inhalation |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2611447A2 (fr) | 2013-07-10 |
| WO2012030309A2 (fr) | 2012-03-08 |
| TR201007251A2 (tr) | 2012-03-21 |
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