WO2018152737A1

WO2018152737A1 - Dose detection system and dose detection method

Info

Publication number: WO2018152737A1
Application number: PCT/CN2017/074567
Authority: WO
Inventors: 比丽尔•理查德•珍•玛丽
Original assignee: 创新精密仪器有限公司
Priority date: 2017-02-23
Filing date: 2017-02-23
Publication date: 2018-08-30

Abstract

A dose detection system (10), comprising: a detection device (102), an electronic device (106), and a database (110). The detection device (102) is used to receive a clicking sound of a drug injection device and convert the clicking sound into an audio signal input (104). The electronic device (106) compares the audio signal input (104) to a first voice print in the database (110) to determine a preconfigured injection dosage corresponding to the audio signal input (104). The dose detection system can accurately detect an actual dosage administered to a patient and has high detection accuracy. A dose detection method, comprising: step S101: storing at least one first voice print generated by a drug injection device when injecting a preconfigured injection dosage; step S102: detecting a clicking sound to acquire an audio signal input; step S103: receiving the audio signal input, and determining, by comparing the audio signal input to the first voice print, the corresponding preconfigured injection dosage; and step S104: indicating the preconfigured injection dosage corresponding to the audio signal input.

Description

Title of Invention: Dose Detection System and Dose Detection Method

Technical field

[0001] The present invention belongs to the field of dose detection technology, and more particularly to a dose detection system and a dose detection method.

Background technique

[0002] In order to facilitate the user's ability to inject drugs by themselves, various forms of injection pens are ejected. In general, the injection pen has an injection dose adjustment knob and an injection unit. The injection dose adjustment knob is used to adjust and set the injected dose. The injection unit is used for injection according to the injection dose set by the injection dose adjustment knob. For example, the injection unit can include a piston for pushing the drug out of the needle for injection. When the injection dose adjustment knob is rotated to the predetermined scale 吋, the movement stroke of the piston is set. When the user presses the injection dose adjustment knob 吋, the injection dose adjustment knob rotates and lowers the lower pressure piston to a predetermined position, thereby completing the injection.

[0003] For disease management in patients, it is important to inject the appropriate drug dose during the correct date. Taking diabetes as an example, it is important to inject an appropriate dose of insulin at the appropriate time. In order to determine the effect of insulin administration, healthcare professionals are encouraged to record the dose and day of each injection. However, since the existing injection device cannot record the injected dose of the drug and the injection time, the patient can only record to the notebook by handwriting. If the patient forgets to record or record an error, it will mislead the health care provider's future medical treatment decisions.

[0004] In the prior art, most of the detecting devices use sensors or optical recognition to detect the moving distance of the piston rod and convert the detection result into electronic data. Because the calculation result is directly affected by the moving distance of the detecting piston rod, the detecting device needs high installation precision and needs to perform complicated calculation, so it may easily cause detection error, and such detecting device cannot meet the user's record at the same time. demand.

technical problem

[0005] It is an object of the present invention to provide a dose detection system for solving the problem of detection errors of existing detection devices.

Problem solution

Technical solution In order to solve the above technical problem, the present invention provides a dose detecting system for detecting an injection dose of a drug injection device, the drug injection device generating at least one click during setting and/or pushing out the injection dose. Sound, the dose detection system includes:

[0007] a detecting device, detachably connected to the drug injection device, configured to detect the click sound to obtain an audio input;

[0008] an electronic device coupled to the detecting device via a wireless network, configured to receive the audio input; and [0009] a database coupled to the electronic device, configured to be populated by the drug injection device At least one first voiceprint produced during the injection of the dose;

[0010] wherein the audio input and the first voiceprint are respectively composed of at least one click sound, and the electronic device compares the audio input and the first voiceprint to determine the audio input. Corresponding said predetermined injection dose, and displaying said predetermined injection dose corresponding to said audio input.

Advantageous effects of the invention

Beneficial effect

[0011] The beneficial effects of the dose detection system provided by the present invention are:

[0012] Since the drug injection device generates at least one click sound during setting and/or pushing the injection dose, the above-described dose detection system uses a detecting device to capture the click sound generated when the drug injection device is used, and The click sound is converted into an audio input, and the audio input is transmitted to the electronic device through the wireless network, and the electronic device compares the audio input with at least one first voiceprint stored in the database, if the click included in the audio input The number of sounds is equal to the number of clicks included in the first voiceprint, indicating that the actual dose of the drug injection device matches the predetermined injection dose, and the predetermined injection dose corresponding to the audio input is determined, and the audio input device is displayed. The corresponding predetermined injection dose. In this way, by the cooperation of the detecting device and the electronic device, the above-mentioned dose detecting system can accurately detect the actual dose of the patient, and the detection accuracy is high.

Another object of the present invention is to provide a dose detecting method for detecting an injection dose of a drug injection device, the drug injection device generating at least one click sound during setting and/or pushing out the injection dose. The method of dose detection includes the following steps:

[0014] storing at least one first voiceprint generated during a predetermined injection dose by the drug injection device;

[0015] detecting the click sound to obtain an audio input; Receiving the audio input, comparing the audio input and the first voiceprint to determine the predetermined injection dose corresponding to the audio input;

[0017] displaying the predetermined injection dose corresponding to the audio input;

[0018] wherein the audio input and the first voiceprint are respectively composed of at least one click sound.

[0019] The beneficial effects of the dose detection method provided by the present invention are:

[0020] using the above-described dose detecting method, which first stores at least one first voiceprint generated during a predetermined injection dose by the drug injection device in a database, and then captures a click generated when the drug injection device is used. Sound, and convert the click sound into an audio input, and simultaneously transmit the audio input to the electronic device through the wireless network, and the electronic device compares the audio input with the first voiceprint, if the number of click sounds included in the audio input Equal to the number of clicks included in the first voiceprint, it means that the actual dose of the drug injection device is consistent with the predetermined injection dose, and the predetermined injection dose corresponding to the audio input can be determined, and the corresponding reservation of the audio input is displayed. Injection dose. In this way, the above-mentioned dose detection method can accurately detect the actual application dose of the patient, and the detection accuracy is high.

Brief description of the drawing

DRAWINGS

1 is a schematic structural diagram of a dose detecting system according to an embodiment of the present invention;

2 is a flowchart of a dose detecting method according to a first embodiment of the present invention;

3 is a flowchart of a dose detecting method according to a second embodiment of the present invention;

4 is another flow chart of a dose detecting method according to a second embodiment of the present invention.

[0025] Description of the reference numerals:

[0026] 10 - _ dose detection system;

[0027] 100 - _ drug injection device;

[0028] 102 - _ detecting device;

[0029] 104- _ audio input;

[0030] 106--electronic device;

[0031] 108--wireless network;

[0032] 110- _ database;

[0033] 112- _ processing unit. Embodiments of the invention

The present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It is understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

[0035] As shown in FIGS. 1 to 4, a preferred embodiment of the present invention is provided.

[0036] It is to be noted that when an element is referred to as being "fixed" or "in" another element, it can be directly on the other element or indirectly. When an element is referred to as being "connected" to another element, it can be connected directly to the other element or indirectly connected to the other element.

[0037] It should also be noted that the left, right, upper, lower, and the like orientation terms in this embodiment are only relative concepts or reference to the normal use state of the product, and should not be considered as having limitations. Sexual.

As shown in FIG. 1 , the dose detecting system 10 provided in this embodiment is mainly used for detecting the injected dose of the drug injection device 100 , and the drug injection device 100 is generated during setting and/or pushing the injected dose. At least one click sound, which is typically generated when the internal components of the drug injection device 100 are moved relative to each other.

[0039] Specifically, the dose detecting system 10 includes:

[0040] The detecting device 102 is detachably connected to the drug injection device 100 for detecting a click sound to obtain an audio input 104;

[0041] The electronic device 106 is coupled to the detecting device 102 via the wireless network 108 for receiving the audio input 104;

as well as

[0042] The database 110 is coupled to the electronic device 106 and stores at least one first voiceprint generated during a predetermined injection dose by the drug injection device 100;

[0043] wherein the audio input 104 and the first voiceprint are respectively composed of at least one click sound, and the electronic device 106 compares the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104, and displays the audio input. 104 corresponding predetermined injection dose.

[0044] Since the drug injection device 100 generates at least one click sound during setting and/or ejection of the injected dose,

The dose detecting system 10 uses the detecting device 102 to capture the click sound generated when the drug injecting device 100 is used, and converts the click sound into the audio input 104, and simultaneously, the audio is transmitted through the wireless network 108. The input 104 is transmitted to the electronic device 106, and the electronic device 106 compares the audio input 104 with at least one first voiceprint stored in the database 110, if the number of clicks included in the audio input 104 is the same as the first voiceprint If the number of clicks included is equal, it means that the actual dose of the drug injection device 100 matches the predetermined injection dose, and the corresponding predetermined injection dose of the audio input 104 can be determined, and the corresponding predetermined injection dose of the audio input 104 can be displayed. Thus, by the cooperation of the detecting device 102 and the electronic device 106, the dose detecting system 10 can accurately detect the actual dose of the patient, and the detection accuracy is high.

[0045] As a second embodiment of the present invention, the second embodiment is substantially the same as the first embodiment, except that the database 110 further stores at least one generated during the reference injection dose set by the drug injection device 100. The second voiceprint, the second voiceprint is composed of at least one click sound, and the electronic device 106 compares the audio input 104 and the second voiceprint to determine the corresponding reference injection dose of the audio input 104, and the predetermined injection dose and the reference injection dose. An alignment is made to determine if the predetermined injection dose is correct.

[0046] In this way, the dose detecting system 10 uses the detecting device 102 to capture the click sound generated when the drug injecting device 100 is used, and then compares one or more preset voiceprints to obtain the corresponding click. The injected dose of sound. In particular, the detecting device 102 can distinguish the two different sounds generated by the drug injection device 100, that is, the sound generated by the predetermined injection dose 吋 and the sound generated by setting the reference injection dose ,, that is, by the drug injection device 100. The first voiceprint generated during the predetermined injection dose and the second voiceprint generated during the reference injection dose set by the drug injection device 100 are pushed out, and then the audio input 104 is respectively input to the first voiceprint and the first by the electronic device 106. The two voice patterns are compared to obtain a predetermined injection dose and a reference injection dose corresponding to the click sound, and if the number of click sounds included in the audio input 104 is equal to the number of click sounds included in the first voice print, The number of clicks included in the audio input 104 is equal to the number of clicks included in the second voiceprint, indicating that the actual dose of the drug injection device 100 matches the predetermined injection dose and the reference injection dose, that is, the predetermined injection. The dose is the actual application dose. Thus, by the cooperation of the detecting device 102 and the electronic device 106, that is, by the double comparison of the click sound generated by the drug injection device 100 with the first voiceprint and the second voiceprint, the dose detecting system 10 can be enabled. More accurate detection of the actual dose of the patient, the detection accuracy is higher.

The specific structure of the detecting device 102 in the first embodiment and the second embodiment may be: The detecting device 102 includes: [0048] an acoustic sensor, the number of which is set to at least one, for converting an acoustic signal represented by the click sound into an electrical signal represented by the audio input 104;

[0049] The wireless communication module is coupled to the wireless network 108 for transmitting the audio input 104 to the electronic device 106.

[0050] In detail, the acoustic sensor may be a sound pressure sensor that converts the surface vibration of the acoustic emission wave into a voltage signal based on the piezoelectric effect of the crystal.

The specific structure of the electronic device 106 in the first embodiment and the second embodiment may be: The electronic device 106 is any one of a server, a smart phone or a computer. When the drug injection device 100 introduces a predetermined injection dose, the electronic device 106 compares the at least one first voiceprint of the audio input 104 and the database 110 to determine the predetermined injection dose corresponding to the audio input 104. Moreover, after the user sets a reference injection dose through the drug injection device 100, the electronic device 106 can also compare the at least one second voiceprint of the audio input 104 and the database 110 to determine the corresponding reference injection dose of the audio input 104. Then, the electronic device 106 compares the corresponding predetermined injection dose and the reference injection dose of the audio input 104 to determine whether the corresponding predetermined injection dose is correct.

Specifically, the electronic device 106 includes: a processing unit 112, configured to respectively obtain the number of click sounds included in each of the audio input 104, the first voiceprint, and the second voiceprint. The number of clicks included in the first voiceprint corresponds to a predetermined injection dose, and the number of click sounds included in the second voiceprint corresponds to a reference injection dose.

Specifically, the wireless network 108 in the foregoing first embodiment and the second embodiment may be: the wireless network 108 includes any one of a cellular communication network, a near field communication network, a Bluetooth network, and a wireless local area network, and two Kind or more.

[0054] As shown in FIG. 1 and FIG. 2, the embodiment further provides a dose detecting method for detecting an injection dose of the drug injection device 100, and the drug injection device 100 sets and/or pushes an injection dose. At least one click is generated during the period.

[0055] Specifically, the dose detection method includes the following steps:

[0056] Step S101: storing at least one first voiceprint generated during the ejection of the predetermined injection dose by the drug injection device 100;

[0057] Step S102: detecting a click sound to obtain an audio input 104; [0058] wherein, the audio input 104 and the first voiceprint are respectively composed of at least one click sound.

[0059] In the step of detecting the click sound to obtain the audio input 104, the acoustic sensor is used to detect the click sound to obtain the audio input 104.

[0060] Step S103: Receive an audio input 104, compare the audio input 104 and the first voiceprint to determine the audio input.

4 corresponding predetermined injection doses;

[0061] The step of comparing the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104 is specifically: determining the number of click sounds included in the audio input 104 and the first voiceprint included Whether the number of click sounds is equal, if equal, the actual application dose of the output medicine injection device 100 is consistent with the predetermined injection dose, and the predetermined injection dose is the actual application dose. If not, the actual application dose is incorrect.

[0062] The electronic device 106 receives the audio input 104, compares the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104. In the same manner, after the step of detecting the click sound to obtain the audio input 104, and before the step of receiving the audio input 104, the method further includes: connecting the electronic device 106 to the electronic device 106 by using the wireless network 108, and transmitting the audio input 104 to the electronic device 106. . The step of receiving the audio input 104 is specifically: receiving the audio input 104 by way of the wireless network 108. The wireless network 108 includes any one of a cellular communication network, a near field communication network, a Bluetooth network, and a wireless local area network, two or more

[0063] Step S104: Display a corresponding predetermined injection dose of the audio input 104;

[0064] wherein the electronic device 106 displays the corresponding predetermined injection dose of the audio input 104.

[0065] Preferably, the predetermined injection dose can be displayed by the electronic device 106 in text or a chart.

[0066] using the above-described dose detecting method, which first stores in the database 110 at least one first voiceprint generated during the ejection of the predetermined injection dose by the drug injection device 100, and then, when using the drug injection device 100 The generated click sound is converted into the audio input 104, and the audio input 104 is transmitted to the electronic device 106 via the wireless network 108, and the electronic device 106 compares the audio input 104 with the first voiceprint. The number of clicks included in the audio input 104 is equal to the number of clicks included in the first voiceprint, indicating that the actual dose of the drug injection device 100 matches the predetermined injection dose, and the corresponding audio input 104 can be determined. The injected dose is predetermined and the corresponding predetermined injection dose for the audio input 104 is displayed. In this way, the above-mentioned dose detection method can accurately detect the patient's reality. The application dose is high, and the detection accuracy is high.

[0067] Furthermore, as shown in FIG. 1, FIG. 3 and FIG. 4, as a second embodiment of the above-described dose detecting method, in step S101: storing at least one generated during the ejection of the predetermined injection dose by the drug injection device 100 After the step of the first voiceprint, and step S102: before detecting the click sound to obtain the audio input 104, further comprising the step S1011: storing at least one second sound generated during the setting of the reference injection dose by the drug injection device 100 a pattern, wherein the second voiceprint is composed of at least one click sound;

[0068] After step S103: receiving the audio input 104, comparing the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104, and step S104: correspondingly presetting the audio input 104 Before the injection dose, the method further includes a step S1031: comparing the audio input 104 and the second voiceprint to determine a corresponding reference injection dose of the audio input 104, and comparing the predetermined injection dose with the reference injection dose to determine whether the predetermined injection dose is correct. .

[0069] After the step of receiving the audio input 104, and before the step of comparing the audio input 104 and the first voiceprint to determine a predetermined injection dose corresponding to the audio input 104, the method further includes: separately obtaining the audio input 104, The number of click sounds included in each of the first voiceprint and the second voiceprint.

[0070] Moreover, the step of comparing the predetermined injection dose and the reference injection dose to determine whether the predetermined injection dose is correct is specifically:

[0071] determining whether the number of click sounds included in the audio input 104 is equal to the number of click sounds included in the first voiceprint and the number of click sounds included in the second voiceprint, and if equal, outputting the drug injection device The actual application dose of 100 is consistent with the predetermined injection dose and the reference injection dose, and the predetermined injection dose is the actual application dose. If they are not equal, the actual application dose is incorrect.

[0072] using the above-described dose detecting method, which first stores in the database 110 at least one first voiceprint generated during the ejection of the predetermined injection dose by the drug injection device 100 and the reference injection dose period set by the drug injection device 100. At least one second voiceprint is generated, and then, the click sound generated when the drug injection device 100 is used is captured, and the click sound is converted into the audio input 104, and the audio input 104 is transmitted to the electronic device via the wireless network 108. The device 106, the electronic device 106 compares the audio input 104 with the first voiceprint and the second voiceprint, respectively, if the number of clicks included in the audio input 104 is equal to the number of clicks included in the first voiceprint Similarly, the number of clicks included in the audio input 104 is equal to the number of clicks included in the second voiceprint, indicating the actual dose of the drug injection device 100 and the predetermined injection. The dose and the reference injection dose are all consistent, that is, the predetermined injection dose is the actual application dose. Thus, by the above-mentioned dose detecting method, the actual hitting dose of the patient can be more accurately detected by the double comparison of the click sound generated by the drug injection device 100 with the first voiceprint and the second voiceprint respectively. The detection accuracy is only the preferred embodiment of the present invention, and is not intended to limit the present invention. Any modifications, equivalent replacements, and improvements made within the spirit and principles of the present invention should be included in the present invention. Within the scope of protection of the present invention.

Claims

Claim

[Claim 1] A dose detecting system for detecting an injection dose of a drug injection device, the drug injection device generating at least one click sound during setting and/or pushing out the injection dose, wherein The dose detection system includes:

a detecting device, detachably connected to the drug injection device, configured to detect the click sound to obtain an audio input;

An electronic device coupled to the detecting device via a wireless network for receiving the audio input;

a database, coupled to the electronic device, storing at least one first voiceprint generated during a predetermined injection dose by the drug injection device;

The audio input and the first voiceprint are respectively composed of at least one click sound, and the electronic device compares the audio input and the first voiceprint to determine a corresponding position of the audio input. The predetermined injection dose is described, and the predetermined injection dose corresponding to the audio input is displayed.

[Claim 2] The dose detecting system according to claim 1, wherein the database stores at least one second voiceprint generated during a reference injection dose set by the drug injection device, The second voiceprint is composed of at least one of the click sounds, and the electronic device compares the audio input and the second voiceprint to determine the reference injection dose corresponding to the audio input, and compares the predetermined The injected dose and the reference injected dose are compared to determine if the predetermined injected dose is correct.

3. The dose detecting system according to claim 2, wherein the detecting means comprises an acoustic sensor, the number of which is set to at least one, for converting the sound signal represented by the click sound An electrical signal represented by the audio input;

a wireless communication module coupled to the wireless network for transmitting the audio input to the electronic device.

[Claim 4] The dose detecting system according to claim 2, wherein the electronic device comprises And a processing unit, configured to respectively obtain the number of the click sounds included in each of the audio input, the first voiceprint, and the second voiceprint.

The dose detecting system according to any one of claims 1 to 4, wherein the electronic device is any one of a server, a smart phone, or a computer.

[Claim 6] The dose detecting system according to any one of claims 1 to 4, wherein the wireless network comprises any of a cellular communication network, a near field communication network, a Bluetooth network, and a wireless local area network. One, two or more.

[Claim 7] A dose detecting method for detecting an injected dose of a drug injection device, the drug injection device generating at least one click sound during setting and/or pushing out the injected dose, wherein The dose detection method includes the following steps:

Storing at least one first voiceprint generated during a predetermined injection dose by the drug injection device;

Detecting the click sound to obtain an audio input;

Receiving the audio input, comparing the audio input and the first voiceprint to determine the predetermined injection dose corresponding to the audio input;

Displaying the predetermined injection dose corresponding to the audio input; wherein the audio input and the first voiceprint are respectively composed of at least one click sound.

The method for detecting a dose according to claim 7, wherein the step of comparing the audio input and the first voiceprint to determine a predetermined injection dose corresponding to the audio input is: Whether the number of the click sounds included in the audio input is equal to the number of the click sounds included in the first voice print, and if they are equal, outputting the actual application dose of the drug injection device and the predetermined injection The dose is consistent.

[Claim 9] The dose detecting method according to claim 7 or 8, wherein after the step of storing at least one first voice print generated during the ejection of the predetermined injection dose by the drug injection device And before the step of detecting the click sound to obtain an audio input, further comprising: storing at least one second voiceprint generated during a reference injection dose set by the drug injection device, wherein The second voice pattern is composed of at least one of the click sounds; and the receiving the audio input, comparing the audio input and the first voiceprint to determine After the step of inputting the predetermined injection dose corresponding to the audio input, and before the displaying the predetermined injection dose corresponding to the audio input, the method further comprises: comparing the audio input and the second sound Tracing to determine the reference injection dose corresponding to the audio input, and comparing the predetermined injection dose and the reference injection dose to determine whether the predetermined injection dose is correct.

[Aspect 10] The dose detecting method according to claim 9, wherein the step of comparing the predetermined injection dose and the reference injection dose to determine whether the predetermined injection dose is correct Specifically:

Determining whether the number of the click sounds included in the audio input is equal to the number of the click sounds included in the first voice print and the number of the click sounds included in the second voice print, If they are equal, the actual applied dose outputting the drug injection device is consistent with the predetermined injection dose and the reference injection dose.

The method for detecting a dose according to claim 7 or 8, wherein in the step of detecting the click sound to obtain an audio input, the click sensor is used to detect the click sound. The audio input.

The method for detecting a dose according to claim 7 or 8, wherein the step of detecting the click sound to obtain an audio input, and the step of receiving the audio input The method further includes: transmitting, by the wireless network, an electronic device to transmit the audio input to the electronic device.

The method according to claim 7 or 8, wherein after the step of receiving the audio input, and comparing the audio input with the first Before the step of determining the predetermined injection dose corresponding to the audio input, the method further comprises: respectively obtaining the clicks included in the audio input, the first voiceprint and the second voiceprint respectively The number of sounds.

The method for detecting a dose according to claim 7 or 8, wherein the step of receiving the audio input is specifically: receiving the audio input by means of a wireless network.

[Claim 15] The dose detecting method according to claim 14, wherein the wireless network comprises any one of a cellular communication network, a near field communication network, a Bluetooth network, and a wireless local area network. Kind, two or more.