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WO2025212909A1 - Fraise composite et ses méthodes d'utilisation pour éliminer un tissu dur - Google Patents

Fraise composite et ses méthodes d'utilisation pour éliminer un tissu dur

Info

Publication number
WO2025212909A1
WO2025212909A1 PCT/US2025/022986 US2025022986W WO2025212909A1 WO 2025212909 A1 WO2025212909 A1 WO 2025212909A1 US 2025022986 W US2025022986 W US 2025022986W WO 2025212909 A1 WO2025212909 A1 WO 2025212909A1
Authority
WO
WIPO (PCT)
Prior art keywords
abrasive surface
surgical bur
length
abrasive
surgical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2025/022986
Other languages
English (en)
Inventor
Zachary Kemp
Michael GALLIZZI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arthrex Inc
Original Assignee
Arthrex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arthrex Inc filed Critical Arthrex Inc
Publication of WO2025212909A1 publication Critical patent/WO2025212909A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B17/320016—Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes
    • A61B17/32002—Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes with continuously rotating, oscillating or reciprocating cutting instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/16—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans
    • A61B17/1613—Component parts
    • A61B17/1615—Drill bits, i.e. rotating tools extending from a handpiece to contact the worked material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/16—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans
    • A61B17/1662—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans for particular parts of the body
    • A61B17/1671—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans for particular parts of the body for the spine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/16—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans
    • A61B2017/1602—Mills
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320004—Surgical cutting instruments abrasive

Definitions

  • Surgical burs are a known tissue removal tool that includes a shaft that is coupled to a driver that rotates the surgical bur about an axis.
  • the shaft supports a working end that includes features that remove tissue upon rotational contact with the tissue.
  • the shaft is typically long and narrow to facilitate entry of the working end into a body (e.g., through an incision, with or without the assistance of a cannula) and to a surgical site where the tissue to be removed is located.
  • Known surgical burs include different types of working ends, which provide different tissue removal rates.
  • a working end may include cutting flutes (alternating flutes and cutting edges arranged radially about the central axis of the surgical bur).
  • abrasive working surface typically a substrate coated with a plurality of abrasive particles.
  • Cutting flutes typically provide faster/more aggressive tissue removal compared to an abrasive surface.
  • Abrasive surfaces typically provide finer control over which tissue is removed and the amount of tissue that is removed.
  • different surgical burs with different abrasive working surfaces of varying roughness may be used throughout the procedure.
  • a first surgical bur with a rougher working surface may be used to remove a first section of hard tissue.
  • the first surgical bur When approaching sensitive tissue/anatomical structures, the first surgical bur may be removed from the surgical site and replaced with a second surgical bur that has a smoother working surface that is used to remove a second section of hard tissue.
  • the smoother working surface results in the second section of hard tissue being removed more slowly so as to better protect the sensitive tissue/anatomical structures.
  • This disclosure relates to a surgical bur used to remove tissue (e.g., hard tissue) from a surgical site within a body.
  • the surgical bur may be inserted into the body through an incision (with or without the assistance of a cannula forming a stable passage through the incision), and a tip of the surgical bur may be advanced to the surgical site.
  • the tip includes at least two different working surfaces that provide different rates of tissue removal upon contact with tissue.
  • the different working surfaces may include first and second abrasive surfaces, each formed by respective pluralities of particles with different average particles sizes.
  • a surgical bur including a first abrasive surface and a second abrasive surface.
  • the first abrasive surface is formed by first particles having a first average particle size and the second abrasive surface is formed by second particles having a second average particle size that is different from the first average particle size.
  • the surgical bur includes an elongate body with a proximal end and a distal end.
  • the proximal end is opposite the distal end along an axis about which the surgical bur rotates when in use.
  • the first and second average particle sizes are different, and one of the first and second abrasive surfaces is closer to the distal end than the other of the first and second abrasive surfaces is from the distal end. This enables the user of the surgical bur to remove sections of tissue with the different abrasive surfaces without removing one tool from the surgical site and replacing it with another tool.
  • This disclosure further relates to methods of removing tissue. Some embodiments described herein include a method of removing tissue that includes first and second sections of hard tissue.
  • the method includes rotating an elongate body comprising a first abrasive surface and a second abrasive surface about an axis.
  • the first section of hard tissue is removed with the first abrasive surface while rotating the elongate body about the axis.
  • the second section of hard tissue is removed with the second abrasive working surface while rotating the elongate body about the axis.
  • Some surgical methods include removing the first section of hard tissue at a first removal rate, and removing the second section of hard tissue at a second removal rate while maintaining a constant rotation rate of the elongate body about the axis.
  • the first and second abrasive surfaces have different roughness values, which results in different removal rates while maintaining a constant speed.
  • Figure 2 is a side elevation view of a surgical bur with a spherical tip.
  • Figure 3 is an isometric view of another surgical bur with a spherical tip.
  • Figure 4 is a side elevation view of another surgical bur with a spherical tip.
  • Figure 5 is an isometric view of a surgical bur with an ovoid tip.
  • Figure 6 is an isometric view of a surgical bur with a conical tip.
  • Figure 7 is an isometric view of a surgical bur with an inverted conical tip.
  • Figure 8 is an isometric view of a surgical bur with a cylindrical tip.
  • Figure 9 is an isometric view of a surgical bur with a tapered cylindrical tip.
  • Figure 10 is an isometric view of a surgical bur with a multi-shape tip.
  • Figure 11 an isometric view of a surgical bur with a conical tip having a flat distal end.
  • Figure 12 is an isometric view of a surgical bur with an inverted conical tip having a flat distal end.
  • Figure 13 is an isometric view of a surgical bur with a dog bone tip.
  • Figure 14 is an isometric view of a surgical bur with a tip including first, second, and third abrasive surfaces.
  • Figure 15 is an isometric view of a surgical bur with a tip including a transition zone between first and second abrasive surfaces.
  • Figure 16 is an isometric view of the surgical bur illustrated in Figure 1 in use during a surgical procedure, with a second abrasive surface of the surgical bur adjacent a first section of hard tissue.
  • Figure 17 is an isometric view of the surgical bur in use during the surgical procedure illustrated in Figure 16, with the second abrasive surface of the surgical bur removing the first section of hard tissue.
  • Figure 18 is an isometric view of the surgical bur in use during the surgical procedure illustrated in Figure 17, with a first abrasive surface of the surgical bur adjacent a second section of hard tissue.
  • Figure 19 is an isometric view of the surgical bur in use during the surgical procedure illustrated in Figure 18, with the first abrasive surface of the surgical bur removing the second section of hard tissue.
  • Figure 20 is an isometric view of the surgical bur illustrated in Figure 1 in use during a surgical procedure, with a second abrasive surface of the surgical bur adjacent a first section of hard tissue.
  • Figure 21 is an isometric view of the surgical bur in use during the surgical procedure illustrated in Figure 20, with the second abrasive surface of the surgical bur removing the first section of hard tissue.
  • Figure 22 is an isometric view of the surgical bur in use during the surgical procedure illustrated in Figure 21, with a first abrasive surface of the surgical bur adjacent a second section of hard tissue.
  • Figure 23 is an isometric view of the surgical bur in use during the surgical procedure illustrated in Figure 22, with the first abrasive surface of the surgical bur removing the second section of hard tissue.
  • a rotary tissue removal tool may be inserted through an opening (e.g., an incision) in a body to provide access to a surgical site within an interior portion of the body.
  • the multiple abrasive surfaces may be arranged (e.g., on a tip of the elongate body) such that one of the abrasive surfaces is closer to the distal end and another of the abrasive surfaces is closer to the proximal end.
  • Some methods of use of the surgical bur include rotating the elongate body of the surgical bur about an axis (e.g., the axis of elongation and/or the central axis). While rotating the surgical bur, a first section of hard tissue is removed via contact of the first abrasive surface with the first section of hard tissue, and a second section of hard tissue is removed via contact with the second abrasive surface.
  • the first surface roughness may be between 50 grit and 150 grit, e.g., between 70 grit and 140 grit, between 80 grit and 130 grit, or between 100 grit and 120 grit.
  • the first abrasive surface 130 may be formed by first particles 132 that have a first average size.
  • the body 122 includes a substrate 134 that is coated or embedded with the first particles 132.
  • the first particles 132 may be secured to the substrate 134 using methods including but not limited to laser ablation, ion-beam assisted deposition, and radio-frequency plasma deposition.
  • the surgical bur 110 may include a second abrasive surface 140 with a second surface roughness.
  • the second surface roughness may be between 50 and 150 grit, for example between 50 and 100 grit. In terms of upper limits, the second surface roughness may be less than 100 grit, e.g., less than 90 grit, less than 80 grit, less than 70 grit, or less than 60 grit. In terms of lower limits, the second surface roughness may be greater than 50 grit, e.g., greater than 60 grit, greater than 70 grit, greater than 80 grit, or greater than 90 grit.
  • the second surface roughness may be between 50 grit and 150 grit, e.g., between 50 grit and 100 grit, between 55 grit and 90 grit, or between 60 grit and 80 grit.
  • the second abrasive surface 140 may be formed by second particles 142 that have a first average size.
  • a portion of the substrate 134 is coated or embedded with the second particles 142.
  • the second particles 142 may be secured to the substrate 134 using methods including but not limited to laser ablation, ion-beam assisted deposition, and radio-frequency plasma deposition.
  • the first surface roughness and the second surface roughness may be different.
  • the first abrasive surface 130 may be finer (i.e., less rough) than the second abrasive surface 140 (i.e., the second abrasive surface 140 may be coarser than the first abrasive surface 130).
  • the first average particle size may be less than the second average particle size.
  • one of the abrasive surfaces e.g., the first abrasive surface 130
  • the first average size may be less than 100 percent of the second average size, e.g., less than 90 percent, less than 80 percent, less than 70 percent, or less than 60 percent. In terms of lower limits, the first average size may be greater than 50 percent of the second average size, e.g., greater than 60 percent, greater than 70 percent, greater than 80 percent, or greater than 90 percent. In terms of ranges, the first average size may be between 50 percent and 100 percent of the second average size, e.g., between 60 percent and 90 percent, or between 70 percent and 80.
  • the different abrasive surfaces of the surgical bur 110 may be arranged separate from one another (e.g., such that there is no overlap between adjacent ones of the different abrasive surfaces) along the body 122.
  • one of the abrasive surfaces e.g., the first abrasive surface 130
  • another of the abrasive surfaces e.g., the second abrasive surface 140
  • the proximal end 126 of the body 122 e.g., forming a second portion or proximal portion 152
  • the first abrasive surface 130 may be finer (e.g., less coarse, having a smaller average particles size, etc.) and positioned closer to the distal end 128 than the second abrasive surface 140, which is coarser (e.g., having a larger average particle size) and positioned closer to the proximal end 126, as shown in Figures 2, 3, 5, 6, 9, 10, 12, 13, 14, and 15.
  • the first abrasive surface 130 may be finer and positioned closer to the proximal end 126, while the second abrasive surface 140 is coarser and positioned closer to the distal end 128, as shown in Figures 4, 7, and 8.
  • the relative positions of the first and second abrasive surfaces 130, 140 are independent from the shape of the body 122, as described in greater detail below. Accordingly, embodiments of the disclosure include surgical burs 110 as shown in each of the illustrated embodiments, but with the positions of the first and second abrasive surfaces 130, 140 reversed.
  • the body 122 of the surgical bur 110 may include a tip 154 and a shaft 156. As shown, the tip 154 may extend distally from the shaft 156 toward the distal end 128 and the shaft 156 may extend proximally away from the tip 154 toward the proximal end 126.
  • the tip 154 may include the different abrasive surfaces (e.g., the first abrasive surface 130 and the second abrasive surface 140).
  • the second abrasive surface 140 may be positioned between the shaft 156 and the distal end 128.
  • the first abrasive surface 130 may be positioned between the shaft 156 and the distal end 128.
  • the body 122 may define a body length L1 measured from the proximal end 126 to the distal end 128 along the first direction D1 (e.g., along the axis 124).
  • the tip 154 may define a tip length L2 measured from the shaft 156 to the distal end 128 along the first direction D1, and the shaft 156 may define a shaft length L3 measured from the tip 154 to the proximal end 126 along the first direction D1.
  • the shaft length L3 is longer than the tip length L2 to enable the tip 154 to be positioned through an incision and/or cannula to reach a surgical site.
  • the surgical bur 110 is not limited to such relative lengths, and some embodiments include a greater tip length L2 than shaft length L3.
  • the first abrasive surface 130 may define a length L4, and the second abrasive surface 140 may define a length L5, each measured along the first direction D1.
  • the length L4 of the first abrasive surface 130 may be about equal (e.g., plus or minus less than five percent) to the length L5 of the second abrasive surface 140, as shown in Figures 2, 3, 4, 5, 9, 10, 13, 14, and 15.
  • the length L4 of the first abrasive surface 130 may be different than (e.g., plus or minus greater than five percent) of the length L5 of the second abrasive surface 140.
  • the length L4 of the first abrasive surface 130 may be greater than the length L5 of the second abrasive surface 140, as shown in Figures 6 and 8.
  • the length L4 of the first abrasive surface 130 may also be less than the length L5 of the second abrasive surface 140, as shown in Figures 7, 11, and 12.
  • the relative lengths L4, L5 of the first and second abrasive surfaces 130, 140 are independent from the shape of the body 122, as described in greater detail below. Accordingly, embodiments of the disclosure include surgical burs 110 as shown in each of the illustrated embodiments, but with the relative lengths L4, L5 of the first and second abrasive surfaces 130, 140 reversed and/or equal to one another.
  • the tip 154 may define an outer perimeter 158 within a longitudinal plane P that is parallel to the axis 124.
  • the axis 124 may lie entirely within the longitudinal plane P, according to some embodiments.
  • the surgical bur 110 may be symmetric about the longitudinal plane P.
  • the surgical bur 110 may be radially symmetric about the axis 124.
  • the outer perimeter 158 may define a length (e.g., the tip length L2) and a width W1 measured perpendicular to length L2. Both the length L2 and width W1 of the outer perimeter 158 may be measured within the longitudinal plane P.
  • the first abrasive surface 130 may define a width W2 having a first maximum dimension
  • the second abrasive surface 140 may define a width W3 having a second maximum dimension.
  • the second maximum dimension of the width W3 may be greater than the first maximum dimension of the width W2, as shown in Figures 6, 7, and 11. According to other embodiments, the second maximum dimension of the width W3 may be less than the first maximum dimension of the width W2, as shown in Figures 10 and 12. Alternatively, the second maximum dimension of the width W3 may be substantially equal to (e.g., plus or minus less than five percent) the first maximum dimension of the width W2, as shown in Figures 2, 3, 4, 5, 8, 9, 13, 14, and 15. [0060] According to some embodiments, the width W1 of the outer perimeter 158 may be tapered, decreasing along the length L2 of the tip 154 in a direction toward the distal end 128, as shown in Figures 6, 9, and 11.
  • the outer perimeter 158 may be substantially conical, or a tapered cylinder.
  • the outer perimeter 158 may be an inversely tapered, increasing along the length L2 of the tip 154 in a direction toward the distal end 128, as shown in Figures 7 and 12.
  • the outer perimeter 158 may be an inverted cone or pear shaped.
  • the width W1 of the outer perimeter 158 may be constant along all or a portion of the length L2 of the tip 154 in a direction toward the distal end 128, as shown in Figures 8, 9, 10, 14, and 15.
  • the outer perimeter 158 may be substantially cylindrical.
  • the outer perimeter 158 may include a double taper (e.g., increasing to a maximum along the length L2 of the tip 154 in a direction toward the distal end 128 and then decreasing from the maximum along the length L2 of the tip 154 along the direction toward the distal end 128), as shown in Figures 2, 3, 4, and 5.
  • the outer perimeter 158 may be substantially spherical or ovoidal.
  • the outer perimeter 158 may include an inverted double taper (e.g., decreasing to a minimum along the length L2 of the tip 154 in a direction toward the distal end 128 and then increasing from the minimum along the length L2 of the tip 154 along the direction toward the distal end 128), as shown in Figure 13.
  • the outer perimeter 158 may have a dog bone shape. Other shapes of the outer perimeter 158 are included in embodiments of the surgical bur 110. For example, mutli-shapes or combinations of one or more of the outer perimeters 158 above (e.g., a partial sphere and a partial cylinder as shown in Figure 10) may cooperatively form the outer perimeter 158 of the surgical bur 110.
  • the outer perimeter 158 may include a flat surface 160. As shown in Figure 12, the flat surface 160 may form the distal end 128 of the body 122. One of the abrasive surfaces (e.g., the first abrasive surface 130, as shown) may be positioned within the flat surface 160.
  • the first particles 132 may be disposed on the flat surface 160 and the second particles 142 may be disposed on a radial wall 162 that encircles the axis 124.
  • the flat surface 160 may include some of the particles of one of the abrasive surfaces, while a remainder of the particles of the one abrasive surface are disposed on the radial wall 162.
  • the specific combinations of outer perimeter 158, relative widths W2, W3 of the first and second abrasive surfaces 130, 140 relative lengths L4, L5 of the first and second abrasive surfaces 130, 140, and relative positions of the first and second abrasive surfaces 130, 140 may be independent from each other.
  • embodiments of the disclosure include outer perimeters 158 as shown in each of the illustrated embodiments, but with the relative widths W2, W3, lengths L4, L5, positions, or any combination thereof of the first and second abrasive surfaces 130, 140 reversed or changed to match what is shown for other shapes of the outer perimeter 158.
  • the surgical bur 110 may include additional sections of abrasive and/or smooth, non-abrasive portions.
  • the tip 154 may include a non-abrasive surface 164 positioned between the first abrasive surface 130 and the second abrasive surface 140, as shown in Figure 3.
  • the non-abrasive surface 164 may be described as an intermediate portion.
  • Embodiments of the surgical bur 110 with other sizes and positions of the non-abrasive surface 164 are included within the present disclosure.
  • the surgical bur 110 may include an intermediate portion 166 (e.g., positioned between the distal portion 150 and the proximal portion 152.
  • the intermediate portion 166 may include a third abrasive surface 168 (e.g., with a surface roughness between that of the first abrasive surface 130 and the second abrasive surface 140), as shown in Figure 14.
  • the intermediate portion 166 may include a transition zone in which the surface roughness gradually changes along the tip length L2 (e.g., from the surface roughness of the first abrasive surface 130 to the surface roughness of the second abrasive surface 140), as shown in Figure 15.
  • a method of removing tissue that includes a first section of hard tissue 200 and a second section of hard tissue 202 may include use of the surgical bur 110.
  • the body 122 of the surgical bur 110 may be rotated (e.g., about the axis 124). Rotation of the body 122 may include attachment of the surgical bur 110 to the drill/driver 112 (as shown in Figure 1) or some other source of rotation.
  • the method may include removing the first section of hard tissue 200 with one of the abrasive surfaces of the tip 154 (e.g., the second abrasive surface 140 as shown in Figures 17 and 21), wherein the removing is conducted by rotating the body 122 about the axis 124 and bringing the rotating second abrasive surface 140 into rotating contact with the first section of hard tissue 200.
  • the method may further include removing the second section of hard tissue 202 with another of the abrasive surfaces of the tip 154 (e.g., the first abrasive surface 130 as shown in Figures 19 and 23). Similar to removal of the first section of hard tissue 200, removing the second section of hard tissue 202 is conducted by rotating the body 122 about the axis 124 and bringing the rotating first abrasive surface 130 into rotating contact with the second section of hard tissue 202. [0069] According to the method, the first section of hard tissue 200 may be removed at a first removal rate, and the second section of hard tissue 202 may be removed at a second removal rate.
  • the first and second removal rates may be different (e.g., with the finer abrasive surface having a slower removal rate and the coarser abrasive surface having a faster removal rate).
  • the first and second removal rates may be independent from a rotational speed of the surgical bur 110.
  • the surgical bur 110 may be rotated at a constant speed while removing the first section of hard tissue 200 at the first removal rate, and removing the second section of hard tissue 202 at the second removal rate.
  • the first section of hard tissue 200 and the second section of hard tissue 202 may be adjacent portions of the same bone (e.g., a vertebral body).
  • any or some of the components or steps disclosed herein may be considered optional.
  • the disclosed compositions may expressly exclude any or some of the aforementioned elements or steps in this description, e.g., via claim language.
  • claim language may be modified to recite that the disclosed surgical burs and/or methods, etc., do not utilize or comprise particles with average particles sizes.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne des composants, des systèmes et des méthodes pour éliminer un tissu dur d'un site chirurgical à l'intérieur d'un corps à travers une incision dans le corps. L'invention concerne une fraise chirurgicale comprenant un corps comportant une pointe avec de multiples surfaces abrasives. La pointe comprend une première surface abrasive (130) ayant une première rugosité de surface et une deuxième surface abrasive (140) ayant une deuxième rugosité de surface, la rugosité de surface des première et deuxième surfaces abrasives correspondant à des tailles de particule moyennes des particules qui forment les première et deuxième surfaces abrasives. Un procédé d'utilisation comprend l'ablation d'une première section de tissu dur avec l'une des surfaces abrasives et l'ablation d'une deuxième section de tissu dur avec une autre surface abrasive sans retirer la pointe du corps.
PCT/US2025/022986 2024-04-05 2025-04-03 Fraise composite et ses méthodes d'utilisation pour éliminer un tissu dur Pending WO2025212909A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202463575339P 2024-04-05 2024-04-05
US63/575,339 2024-04-05

Publications (1)

Publication Number Publication Date
WO2025212909A1 true WO2025212909A1 (fr) 2025-10-09

Family

ID=95554824

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2025/022986 Pending WO2025212909A1 (fr) 2024-04-05 2025-04-03 Fraise composite et ses méthodes d'utilisation pour éliminer un tissu dur

Country Status (1)

Country Link
WO (1) WO2025212909A1 (fr)

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