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ZA9510876B - Transdermal absorption of active substances - Google Patents

Transdermal absorption of active substances

Info

Publication number
ZA9510876B
ZA9510876B ZA9510876A ZA9510876A ZA9510876B ZA 9510876 B ZA9510876 B ZA 9510876B ZA 9510876 A ZA9510876 A ZA 9510876A ZA 9510876 A ZA9510876 A ZA 9510876A ZA 9510876 B ZA9510876 B ZA 9510876B
Authority
ZA
South Africa
Prior art keywords
active substances
transdermal absorption
absorption
agents
skin
Prior art date
Application number
ZA9510876A
Other languages
English (en)
Inventor
Thomas Hille
Original Assignee
Lts Lohmann Therapie Systems G
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6537122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA9510876(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lts Lohmann Therapie Systems G filed Critical Lts Lohmann Therapie Systems G
Publication of ZA9510876B publication Critical patent/ZA9510876B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
ZA9510876A 1994-12-24 1995-12-21 Transdermal absorption of active substances ZA9510876B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4446600A DE4446600A1 (de) 1994-12-24 1994-12-24 Transdermale Resorption von Wirkstoffen aus unterkühlten Schmelzen

Publications (1)

Publication Number Publication Date
ZA9510876B true ZA9510876B (en) 1996-05-10

Family

ID=6537122

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9510876A ZA9510876B (en) 1994-12-24 1995-12-21 Transdermal absorption of active substances

Country Status (12)

Country Link
US (1) US6264980B1 (fr)
EP (1) EP0792145B1 (fr)
JP (1) JP3549207B2 (fr)
AT (1) ATE172640T1 (fr)
AU (1) AU4387196A (fr)
DE (2) DE4446600A1 (fr)
DK (1) DK0792145T3 (fr)
ES (1) ES2125678T3 (fr)
IL (1) IL116452A0 (fr)
SI (1) SI0792145T1 (fr)
WO (1) WO1996019975A1 (fr)
ZA (1) ZA9510876B (fr)

Families Citing this family (47)

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US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
EP1255547B1 (fr) 2000-02-08 2008-08-20 Euro-Celtique S.A. Compositions a liberation regulee contenant des agonistes et antagonistes de l'opioide
JP4659943B2 (ja) 2000-02-25 2011-03-30 帝三製薬株式会社 塩酸ブプレノルフィン含有貼付剤
US7018649B2 (en) 2000-10-23 2006-03-28 Euro-Celtique, S.A. Felodipine transdermal device and methods
EP1335689B1 (fr) 2000-10-23 2010-03-17 Euro-Celtique S.A. Système pour l' administration transdermique de loratadine et son utilisation
EP1368023B1 (fr) * 2001-02-16 2005-12-28 Grünenthal GmbH Utilisation de buprenorphine pour traiter l'incontinence d'urine
WO2002083135A2 (fr) * 2001-02-16 2002-10-24 Grünenthal GmbH Utilisation de la buprenorphine pour la production de systemes de delivrance transdermique servant au traitement de l'incontinence urinaire, et specialement de l'incontinence urinaire due a l'urgence urinaire
EP1323421A1 (fr) * 2001-12-20 2003-07-02 Grünenthal GmbH Utilisation de buprénorphine pour la préparation d'un dispositif pour l'administration transdermique pour le traitement de l'incontinence urinaire, spécialement de l'incontinence instante
JP5160018B2 (ja) 2002-06-25 2013-03-13 アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド 非晶質医薬組成物を用いる経皮送達速度調節
US20050191340A1 (en) * 2002-08-09 2005-09-01 Gruenenthal Gmbh Opioid-receptor antagonists in transdermal systems having buprenorphine
US7084150B2 (en) 2002-10-25 2006-08-01 Euro-Celtique S.A. Analogs and prodrugs of buprenorphine
DE10305137A1 (de) * 2003-02-07 2004-08-26 Novosis Ag Transdermale therapeutische Abgabesysteme mit einem Butenolid
JP2007523167A (ja) 2004-02-23 2007-08-16 ユーロ−セルティーク エス．エイ． 乱用抵抗性の経皮的オピオイド送達デバイス
EP1743638A1 (fr) 2005-07-15 2007-01-17 Laboratorios Del Dr. Esteve, S.A. Formulations pharmaceutiques des derivés de la pyrazoline
KR101329496B1 (ko) 2006-07-21 2013-11-13 바이오딜리버리 사이언시스 인터내셔널 인코포레이티드 향상된 흡수를 갖는 경점막 전달 장치
DE102006054731B4 (de) * 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
DE102006054732B4 (de) 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren
CN107115326B (zh) 2010-04-13 2021-01-22 雷尔玛达治疗股份有限公司 1-甲基-n-(2,6-二甲苯基)-2-哌啶甲酰胺的皮肤用药物组合物及其使用方法
AU2011331511C1 (en) 2010-11-17 2018-01-18 Hexal Ag Transdermal therapeutic system comprising buprenorphine
DE102011076653A1 (de) 2011-05-27 2012-11-29 Acino Ag Transdermales therapeutisches System enthaltend Buprenorphin und eine alpha-Hydroxysäure
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CA2856520C (fr) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Preparations et therapies de substitution pour hormonotherapie naturelle combinee
PL2790685T3 (pl) * 2011-12-12 2018-04-30 Lts Lohmann Therapie-Systeme Ag System dostarczania przezskórnego zawierający buprenorfinę
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CA2882870C (fr) * 2012-08-24 2020-12-15 Integurx Therapeutics, Llc Compositions chimiques et procedes pour ameliorer l'administration transdermique d'agents therapeutiques
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
EP2934497B1 (fr) * 2012-12-21 2016-11-23 Teikoku Pharma USA, Inc. Compositions et méthodes d'administration transdermique d'hormones et d'autres substances médicales
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
EP2938391B1 (fr) 2012-12-28 2022-07-27 Teikoku Seiyaku Co., Ltd. Compositions de buprénorphine à libération transdermique prolongée
WO2014195352A1 (fr) 2013-06-04 2014-12-11 Lts Lohmann Therapie-Systeme Ag Système d'administration transdermique
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
DE102014013448A1 (de) 2014-09-16 2016-03-17 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales Therapeutisches System umfassend Buprenorphin
US9656441B2 (en) 2015-01-08 2017-05-23 Alfred E. Tiefenbacher ( Gmbh & Co. Kg) Transdermal patch
EP3283490A1 (fr) 2015-03-10 2018-02-21 Rhodes Technologies Inc. Sel d'acétate de bruprénorphine et procédés pour la préparation de bruprénorphine
EP3067050A1 (fr) 2015-03-13 2016-09-14 Acino AG Système thérapeutique transdermique avec bande de recouvrement comprenant deux couches adhésives
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
AR102214A1 (es) 2015-10-08 2017-02-15 Amarin Tech S A Un dispositivo para la administración transdermal de buprenorfina
WO2017173044A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Compositions d'hormones stéroïdes dans des huiles à chaîne moyenne
JP2019513709A (ja) 2016-04-01 2019-05-30 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． ステロイドホルモン薬学的組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US4900730A (en) * 1981-01-14 1990-02-13 Toyo Jozo Co., Ltd. Preparation which promotes the absorption of peptides
JPS58124711A (ja) * 1982-01-21 1983-07-25 Kanebo Ltd 皮膚化粧料
DE3315272C2 (de) 1983-04-27 1986-03-27 Lohmann Gmbh & Co Kg, 5450 Neuwied Pharmazeutisches Produkt und Verfahren zu seiner Herstellung
CA2002299A1 (fr) * 1988-11-10 1990-05-10 Eugene G. Drust Composes pour l'administration transdermique de sels de buprenorphine
GB8921710D0 (en) * 1989-09-26 1989-11-08 Mentholatum Co Ltd Ibuprofen triturates and topical compositions containing same
DE3939376C1 (fr) * 1989-11-29 1991-05-08 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De
US5240711A (en) * 1989-11-29 1993-08-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system comprising as active component buprenorphine
US5069909A (en) * 1990-06-20 1991-12-03 Cygnus Therapeutic Systems Transdermal administration of buprenorphine
DE4238223C1 (de) * 1992-11-12 1994-05-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Verabreichung von Physostigmin an die Haut und Verfahren zu dessen Herstellung

Also Published As

Publication number Publication date
EP0792145B1 (fr) 1998-10-28
SI0792145T1 (en) 1999-10-31
DE59504097D1 (de) 1998-12-03
DE4446600A1 (de) 1996-06-27
JP3549207B2 (ja) 2004-08-04
DK0792145T3 (da) 1999-07-12
US6264980B1 (en) 2001-07-24
EP0792145A1 (fr) 1997-09-03
ES2125678T3 (es) 1999-03-01
IL116452A0 (en) 1996-03-31
ATE172640T1 (de) 1998-11-15
JPH10512551A (ja) 1998-12-02
AU4387196A (en) 1996-07-19
WO1996019975A1 (fr) 1996-07-04

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