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Compare the Top Crypto APIs in the USA as of October 2025

What are Crypto APIs in the USA?

Crypto APIs are application programming interfaces (APIs) that allow developers to interact with and integrate various cryptocurrency-related services into their applications. These APIs provide access to cryptocurrency data such as live price feeds, transaction details, wallet management, and blockchain data. They also support functionality like trading, payments, currency conversions, and smart contract interactions. Crypto APIs are widely used in applications for cryptocurrency exchanges, wallets, price tracking apps, and decentralized finance (DeFi) platforms, simplifying the integration of blockchain and crypto services for developers. Compare and read user reviews of the best Crypto APIs in the USA currently available using the table below. This list is updated regularly.

  • 1
    Sila

    Sila

    Sila

    Sila is an end-to-end payment platform that provides Banking-as-a-Service through a developer-friendly payment API that is scalable and allows for fast and secure money transfers. Sila’s payment platform streamlines building and launching fintech apps and embedded payment products for financial products, fintech, crypto, and Web3. Sila’s offerings include Virtual Accounts, Digital Wallets, KYC/KYB, and ACH payments APIs for software teams. Additional functionality is available through a network of pre-approved and pre-integrated partners (to different degrees). Sila was recognized as the Best Payments as a Service Platform by the 2022 Embedded Banking Awards of Tearsheet. Sila is headquartered in Portland, Oregon.
  • 2
    Prime Trust

    Prime Trust

    Prime Trust

    Prime Trust's universal asset platform is built on our proprietary core system, allowing for the custody of a wide range of various assets traditional institutions struggle to represent properly. As the fintech landscape continues to evolve, many applications are expanding beyond traditional USD payments, banking, and custody; and beginning to incorporate a wide range of assets from crypto to securities. With PrimeCore, all those assets can be custodied in one account for maximum convenience and ease of integration. Consumers demand flexibility and PrimeCore's account types deliver. Starting from simple custodial accounts for individuals and institutions, Prime core goes beyond traditional Banking-as-a-Service infrastructure with tax advantaged accounts like IRAs as well as securing through a variety of different asset protection trusts. As an independent, qualified custodian, we are the industry's trusted provider of secure storage solutions for traditional and modern assets.
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