Best B2B eCommerce Platforms in the USA
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Compare the Top B2B eCommerce Platforms in the USA as of October 2025
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What are B2B eCommerce Platforms in the USA?
B2B ecommerce platforms are digital solutions that enable businesses to conduct online transactions with other businesses, focusing on bulk buying and selling, wholesale pricing, and complex procurement processes. These platforms allow businesses to create customized catalogs, manage pricing for different customers or customer segments, and streamline the ordering process. Key features often include secure payment gateways, order tracking, inventory management, and integration with backend systems like ERP and CRM. B2B ecommerce platforms are designed to handle large volumes of orders, facilitate negotiations, and provide business buyers with self-service options for placing orders, managing accounts, and tracking deliveries. They are ideal for businesses looking to expand their reach, optimize purchasing workflows, and build long-term relationships with clients. Compare and read user reviews of the best B2B eCommerce platforms in the USA currently available using the table below. This list is updated regularly.
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Shopify
Shopify
Shopify is a leading all-in-one commerce platform that enables businesses to start, build, and grow their online and physical stores. It offers tools to create customized websites, manage inventory, process payments, and sell across multiple channels including online, in-person, wholesale, and global markets. The platform includes integrated marketing tools, analytics, and customer engagement features to help merchants reach and retain customers. Shopify supports thousands of third-party apps and offers developer-friendly APIs for custom solutions. With world-class checkout technology, Shopify powers over 150 million high-intent shoppers worldwide. Its reliable, scalable infrastructure ensures fast performance and seamless operations at any business size.">
Starting Price: $29 per month -
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Now Commerce
Now Commerce
Elevate your wholesale operations by transitioning your customers from phone and email orders to a seamless online experience. Designed specifically for wholesalers, manufacturers, and distributors utilizing QuickBooks, the Now Commerce B2B Customer Portal empowers your wholesale accounts to effortlessly place orders online through your branded portal. Orders placed online are seamlessly integrated into QuickBooks, significantly reducing your order entry workload. Now Commerce is fully compatible with both QuickBooks Desktop and QuickBooks Online. With secure, invitation-only access, your wholesale customers can navigate personalized, customer-specific order guides featuring precise product numbers, comprehensive descriptions and images, real-time inventory insights, and tailored pricing. Through self-service, they can easily verify the status of open orders, access delivery or tracking details, and review past orders and payments.Starting Price: $150-$280/m after free trial -
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Pepperi
Advantive
The #1 B2B sales platform for medium, large and enterprise consumer goods manufacturers and distributors. Pepperi is a comprehensive, unified commerce platform to manage all aspects of your B2B sales. We combine a B2B eCommerce storefront, sales rep app for mobile order-taking (iOS/Android), Trade Promotions module, Retail Execution, Route Accounting / DSD & Inside Sales - in ONE UNIFIED cloud-based platform that runs online and offline to maximize in-person and online B2B sales. Thanks to its proprietary IPaaS (Integration Platform as a Service), Pepperi syncs seamlessly to your existing tech stack such as ERPs, Accounting software, Payment and Shipping gateways. Pepperi is the ONLY purpose-built mobile solution on the market and currently serves over 1000 companies in 65 countries.">
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Kentro
Kentro.io
Kentro redefines ERP for the E-Commerce era, offering a cloud-based, multi-channel solution at a fraction of the cost and complexity of traditional systems like NetSuite or SAP. It's user-friendly, efficient, and packed with essential features: real-time inventory management, order fulfillment, built-in B2B stores, comprehensive supply-chain management, and automated accounting. Plus, seamless integration with 100+ tools and 5000+ zaps ensures that Kentro effortlessly connects and automates your business processes. Capabilities include advanced inventory tracking, dynamic order routing, drop-ship automation, and more, all designed to streamline your E-Commerce operations. Experience the future of ERP with Kentro.Starting Price: $225/month -
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SimplyDepo
SimplyDepo
SimplyDepo is a B2B sales and retail execution platform built for CPG brands, distributors, and merchandisers. Designed for field teams, it simplifies order management, retail audits, and route planning in one mobile-first system. Reps can place orders, capture shelf data, and track inventory—even offline. Managers gain real-time insights into performance, sales, and delivery metrics. Key features include: • Centralized product and pricing control • Mobile app for reps with offline support • Smart route planning with map tools • CRM-style customer management • Real-time sales dashboards and reporting No more spreadsheets or disconnected tools—SimplyDepo keeps your wholesale operation aligned, efficient, and ready to grow.Starting Price: Tailored to Your Team’s Needs. -
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TrueCommerce
TrueCommerce
TrueCommerce is the only electronic data interchange (EDI) provider that offers a true one-stop shopping solution for EDI compliance. Affordable, robust, and easy-to-use, TrueCommerce EDI Solution streamlines order processing, reduces manual data-entry errors, and increases employee productivity. The company's core software product, TrueCommerce EDI Transaction Manager, supports any trading partner using ANSI ASC X12 EDI standards and converts business documents (e.g. purchase orders and invoices) into an EDI-compliant format. -
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iM3 Supply Chain Management Suite
PeoplePlus Software
iM3 SCM Suite is a cloud-based set of tools to Digitally Transform Supply Chain of an Enterprise; automation of Warehouse, Distribution Center & 3PL Operations, multi-Channel Order & eCommerce management. We bring expertise to chose technologies from Mobile Computers Scanners & Barcode Printers, Automated Guided Vehicles (AGV) fully integrated with iM3SCM Suite. API integrations into Shipping (Fedex, UPS, USPS, LTL), fleet manager, Accounting Software Quickbooks Online/Desktop, SAGE etc. Digitally Transform your Asset & Facilities, Repair management, Dealer and Distribution management, Field Service & Fleet Management, Yard Management, Rental Management of Assets, Track Technician, Time & Labor and more. iM3 SCM Suite includes Mobile Apps (phones/tablets) to manage various functions of your operations in-house or on the GO. Choose the best technology for your enterprise to improve productivity, efficiency, quality, improved Invoicing & help reduce cost of operations.Starting Price: $100/Month/User -
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BizAutomation
BizAutomation
BizAutomation automates your ENTIRE business without any of the "Good, Better, Best", "Sell by the App", or "Teaser Pricing" shinanigans so prevelant with Big Tech software these days. We're a transparent U.S. based family owned software company with old fashioned values that gets directly involved in our customer's success... Meaning we're a "customer" not "consultant partner" first advocate. If you like where this is going, take a look at our cloud business suite, the most comprehensive in the industry. It includes: Operations management, ERP, Order Management with Shipping & Fulfillment, Procurement, Accounting (no need for QuickBooks), Warehouse Management, Inventory Management, Ecommerce, MRP, and Workflow Automation, all wrapped up in a single cloud suite designed exclusively for growing small businesses. Lastely, our demos are about selling you stuff, they're about genuinely helping you find a solution, whether that's us or not.Starting Price: $79.95/month/user -
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WeSupply Labs
WeSupply Labs
WeSupply Labs helps merchants provide the best post-purchase customer experience when selling online with their integrated services designed to assure a smooth post-purchase experience for end-users. Features Summary: ✓Proactive Notifications of delivery status ✓Package Tracking ✓Returns & RMA ✓Store Locator with complete SEO schema and Social Integration ✓In Store Pickup & Curbside for connecting Ecommerce, ERP and POS ✓Delivery Estimate Algorithm based on historical processing & delivery ✓Customer Satisfaction Score survey and Net Promoter Score ✓Analytics & Statistics for data-driven decisions ✓Branded Tracking Page for a premium self-service tracking experience Integrations: 🔗Magento 2 - Full integration from Order Tracking to Returns and Store Pickup 🔗Shopify - Full integration from Order Tracking and Returns 🔗BigCommerce - Full integration from Order Tracking via Zapier App 🔗Netsuite - Full integration via CeligoStarting Price: $0.03/shipment -
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Cin7 is a web based inventory system that helps businesses manage their inventory anywhere, in real time. Suitable for omni-channel retailers and wholesalers, Cin7 integrates cloud inventory, Point of Sale, warehouse management, B2B ecommerce, 3PL, and direct EDI, in one robust platform. Cin7 also features seamless integrations for Shopify, Magento, Xero, Amazon, Ebay and more.
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inSitu Sales
inSitu Sales
Insitu Sales is a company that specializes in providing innovative sales solutions for businesses in the wholesale, distribution, and manufacturing industries. inSitu Sales provides a comprehensive mobile sales application that features route management, order taking, inventory management, other tools to streamline the sales process. Equip your sales teams with mobile devices and access to real-time data, enabling them to efficiently manage customer interactions, track inventory, and process orders on the go. Providing an all-in-one cloud based mobile order management system with ERP integration (QuickBooks®, Xero, SAP and Excel). Insitu Sales offers B2B eCommerce solutions designed to facilitate online transactions between businesses. Our B2B eCommerce platform provides a user-friendly interface where businesses can create their online catalogs, showcase their products, and enable customers to place orders directly through the platform.Starting Price: $34.99/month/user -
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EasyEcom
EasyEcom
EasyEcom is an omnichannel Inventory Management & Reconciliation solution for eCommerce businesses. EasyEcom helps brands accelerate their digital growth with end-to-end management for inventory, warehousing, payment reconciliation, order management for B2B eCommerce. EasyEcom Provide following Value Add- EasyEcom: Omnichannel Order Processing & Centralized Inventory Management. Inventory Procurement through purchase order management and SKU management. State-of-art warehouse management system to manage order routing, splitting, inventory across multiple warehouse locations with advanced shipping rules. Track and prevent losses of unpaid orders, extra shipping charges, wrong deductions with Automated & accurate payment reconciliation. Accounting automation with auto synchronization with ERP and Tax. Advance reporting and analytics around customers and their buying patterns to identify growth opportunities.Starting Price: $0.49 per order -
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Brahmin Solutions
Brahmin Solutions
Brahmin Solutions is a cloud-based warehouse and inventory management software designed for manufacturers, B2B wholesale distributors, and eCommerce businesses to scale and maximize profits. The system includes tools for managing inventory, replenishment, receiving, stock transfers, order fulfillment, reporting, analytics, forecasting, and multiple eCommerce channels including marketplaces, B2C, and B2B eCommerce.Starting Price: $99/month -
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Cloudmore
Cloudmore
Whether you're a business looking to solve a recurring services procurement challenge, a vendor transitioning to recurring revenue, or a service provider moving to the cloud, Cloudmore has a solution for you. One place to sell, manage and bill your subscription channel partners and customers. Solve the procurement challenge for recurring and metered services. Reduce your billing processing time and remove costly billing errors. Users can self serve to discover and acquire the services they need. Showcase and sell your services in an internal or external marketplace. Select services from Cloudmore's service catalog and sell these to your users in their curated e-store. Manage pricing on a global or per customer basis. Create offers and quotes from your service catalog. Your admin users can discover, provision and manage services and view monthly billing details.Starting Price: 499 -
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QuickBooks Commerce
Intuit
QuickBooks Commerce (formerly TradeGecko) is powerful inventory and order management software, built for multichannel brands and wholesalers. It enables automation for omnichannel operations, improving efficiency and increasing profitability. The QuickBooks Commerce B2B eCommerce platform enables customers to set customized catalogs and price lists, take wholesale orders, and receive payment faster using QuickBooks Commerce Payments. Seamless integrations with Shopify, Xero, QuickBooks Online, Amazon, WooCommerce and more. Customers can automate repetitive and time-consuming workflows allowing them to take control of complex processes and optimize the order management workflow, shipping and logistics with supply chain automation. Other features include intelligence, demand forecasting, and a mobile app for iPhone and iPad. Sell. Ship. Grow. Manage your multi-channel and wholesale business in one place with QuickBooks Commerce.Starting Price: $39.00 per month -
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Webgility
Webgility
Automate your accounting, inventory & shipping across all channels. Ready to Optimize Your Operations—and Maximize Profits? Give Webgility a Try Today. Stop doing busywork. Get back to business. Automate accounting and operations for multi-channel commerce. Automatically post, track, and sync all orders, expenses, fees, and shipping costs directly into QuickBooks Online or QuickBooks Enterprise. Record each order individually or summarized by day, week, month or settlement period with journal entries.Starting Price: $249.00/month -
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Zangerine
Zangerine
Wholesalers in the United States! Automate & optimize your inventory, e-commerce, quotes & shipping from any computer or mobile device. WHAT CAN ZANGERINE DO FOR YOU? * Save money by eliminating errors * Reduce wasted time with automation * Grow sales with more efficient e-Commerce * Upgrade to real-time data that improves decision making * Increase security & accountability * Create competitive advantage with custom features ERP FEATURES * Purchasing * Inventory management * Barcode scanning * CRM * Sales quotes * Process payments * B2B e-Commerce platform * Customer portals * Order management * Multi-warehouse, 3PL & Dropship fulfillment * Pick, pack & shipping labels * RMA management * 58 Preset managerial accounting reports WHAT MAKES ZANGERINE DIFFERENT? * Our software is built specifically to fix the challenges of Wholesalers * Our team helps you go live in just 5 sessions * We are the only ones that GUARANTEE successful implementationStarting Price: $199.00/month -
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Afosto
Afosto
Afosto on an API-first, microservices-based architecture. This modular system lets you build your best-of-breed solution for your particular situation. Create, receive and manage all your B2C and B2B orders in 1 dashboard. Automate your day-to-day tasks and build and automate unique experiences Modern and advanced point of sale made for your brick-and-mortar store. Print your packing slips, shipping labels and invoices automatically via our print API. Sync and transfer inventory across locations, channels, and warehouses, and purchase new inventory. Insights and actions for individuals and organizations all centralized in one system. Structurally improve your business with beautiful BI dashboards. Optimize your images to next-gen formats for increased page speed. Multiple currencies, VAT regimes and languages. You shouldn’t be limited by borders. Neither should your platform. Create cutting-edge international shopping experiences. -
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Mirakl
Mirakl
Platform your business to power your digital transformation. Mirakl is the only marketplace SaaS platform that empowers both B2B and B2C organizations to launch and grow an enterprise marketplace at scale. Mirakl’s best-of-breed SaaS solution automates marketplace operations including seller onboarding, 3rd party catalog integration, distributed order management and seller invoicing & payout without compromising security, performance or quality of experience. We help you develop your marketplace business case & operations strategy. Specialized SaaS platform that automates operations to scale your platform business. A powerful ecosystem of partners, tools, and support to fuel ongoing marketplace success. -
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FitOneBox
Jeevan Infotech India
FITONEBOX is a web-based software application seamlessly integrated across all departments of your company, that can automate your manufacturing and distribution business in a quick time. One smart platform that can seamlessly automate your business and provide complete control. No more hassles of handling multiple software and vendors to streamline your business process. Lower your expenditure by up to 40% compared to any other industry standard on-premise solution. With FIT you have no big charges for customization as this is an industry-specific product with almost all your needs readily available. You will have our latest releases all the time at no extra cost. We are your reliable partner from the conceptualization of the idea all the way to its successful implementation in a short project duration, thanks to FOB's agile project management. The application carries best-of-industry practices and modules with structured data flow control that can be configured as per customer needs. -
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Fynd
Fynd
At Fynd, we build modular tech infrastructure customized to support your omnichannel goals and transform the way you do retail. Fynd is a multiplatform technology company specializing in retail-tech solutions aimed at delivering exceptional customer experiences. The company offers a unified and composable commerce platform that includes products such as Fynd Store OS for smart retail store and staff management, Fynd Storefront for building ecommerce websites, and Fynd Commerce APIs for seamless integrations. Additionally, Fynd provides AI-powered tools for digital asset management and immersive augmented reality solutions. Experience frictionless commerce by unifying all sales channels and stock points to upgrade and scale your commerce capabilities. Simplify retail store management, boost store sales, empower your store staff, and enhance in-store user experiences for your customers, all under one app.
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