gfit News

This minor release fixes incompatibilities with MATLAB R2010

A chapter about gfit is to appear in Systems Biology, a volume in Methods in Molecular Biology published by Humana Press. The editor of the volume is Ivan Maly from the University of Pittsburgh. The chapter discusses operation of gfit and provides step-by-step guides for most common tasks:
- creating computational models for gfit
- importing experimental data
- performing regression analysis

More information about the book can be found here:
http://www.springer.com/humana+press/book/978-1-934115-64-0... read more

rsys is a C++ mex-file library for efficient simulation of reaction kinetics under MATLAB. rsys automatically generates a system of ODEs and solves it using SUNDIALS CVODE library. Using rsys inside gfit models makes it feasible to study more complex systems and larger datasets.

gfit is a program for model-based analysis of experimental data. You can use it for:

- building a model that simulates behavior of any process or system

- fitting the model simultaneously (globally) into many types of experimental measurements

- searching for global minimum

- determining model parameters

- estimating parameter confidence

Many examples of models can be found at http://gfit.sourceforge.net/models.html... read more

A few simple computational models for gfit are now available for download: http://gfit.sourceforge.net/models.html

gfit models are used for simultaneous (global) regression analysis of data from many experiments. The interface allows to assign each parameter to one or to many experiments.

The models are for analysis of Fluorescence Correlation Spectroscopy (FCS) data, for Surface Plasmon Resonance (SPR) binding kinetics, and for kinetics of DNA unwinding by a helicase.... read more