NO306944B1 - Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav - Google Patents
Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse deravInfo
- Publication number
- NO306944B1 NO306944B1 NO962810A NO962810A NO306944B1 NO 306944 B1 NO306944 B1 NO 306944B1 NO 962810 A NO962810 A NO 962810A NO 962810 A NO962810 A NO 962810A NO 306944 B1 NO306944 B1 NO 306944B1
- Authority
- NO
- Norway
- Prior art keywords
- alkyl group
- lower alkyl
- substituted
- derivatives
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/10—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27095794 | 1994-11-04 | ||
| PCT/JP1995/002236 WO1996014293A1 (en) | 1994-11-04 | 1995-11-01 | Novel 1,3-dialkylurea derivative having hydroxyl group |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO962810L NO962810L (no) | 1996-07-03 |
| NO962810D0 NO962810D0 (no) | 1996-07-03 |
| NO306944B1 true NO306944B1 (no) | 2000-01-17 |
Family
ID=17493383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO962810A NO306944B1 (no) | 1994-11-04 | 1996-07-03 | Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5891912A (no) |
| EP (1) | EP0738711B1 (no) |
| KR (1) | KR100376150B1 (no) |
| CN (1) | CN1055681C (no) |
| AT (1) | ATE190304T1 (no) |
| CA (1) | CA2180021A1 (no) |
| DE (1) | DE69515465T2 (no) |
| ES (1) | ES2145929T3 (no) |
| FI (1) | FI962751A7 (no) |
| NO (1) | NO306944B1 (no) |
| WO (1) | WO1996014293A1 (no) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
| US5985968A (en) * | 1997-11-17 | 1999-11-16 | Air Products And Chemicals, Inc. | Surface tension reduction with N,N-dialkyl ureas |
| US6156784A (en) * | 1997-12-18 | 2000-12-05 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compounds useful as phosphotyrosine mimics |
| US6677360B2 (en) | 1998-12-16 | 2004-01-13 | Bayer Aktiengesellschaft | Biphenyl and biphenyl-analogous compounds as integrin antagonists |
| US6420396B1 (en) | 1998-12-16 | 2002-07-16 | Beiersdorf Ag | Biphenyl and biphenyl-analogous compounds as integrin antagonists |
| FR2820136A1 (fr) * | 2001-01-26 | 2002-08-02 | Aventis Pharma Sa | Nouveaux derives de l'uree, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation |
| US6842358B2 (en) * | 2002-08-01 | 2005-01-11 | Netlogic Microsystems, Inc. | Content addressable memory with cascaded array |
| ES2462916T3 (es) | 2002-09-18 | 2014-05-26 | Janssen Pharmaceuticals, Inc. | Métodos para aumentar la producción de células madre hematopoyéticas y plaquetas |
| DE10252650A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Cyclohexyl-Harnstoff-Derivate |
| US7045653B2 (en) * | 2002-12-23 | 2006-05-16 | Pfizer, Inc. | Pharmaceuticals |
| BRPI0409627A (pt) * | 2003-04-21 | 2006-04-25 | Elan Pharm Inc | 2-hidróxi-3-diaminoalcanos de fenacila |
| ME00313B (me) * | 2003-08-28 | 2011-05-10 | Ortho Mcneil Pharm Inc | Peptidi i jedinjenja koja se vežu za receptor |
| GB2425310B (en) * | 2003-12-31 | 2008-04-16 | Council Scient Ind Res | N-aryloxypropanolyl-N' -phenethyl-urea |
| US6962945B2 (en) | 2004-03-26 | 2005-11-08 | Council Of Scientific And Industrial Research | N-aryloxypropanolyl-N′-phenethyl-urea |
| FR2885129B1 (fr) | 2005-04-29 | 2007-06-15 | Proskelia Sas | Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation. |
| ATE450262T1 (de) * | 2005-11-25 | 2009-12-15 | Galapagos Sas | Harnstoff-derivate als calcium-rezeptor- modulatoren |
| GB0613674D0 (en) * | 2006-07-10 | 2006-08-16 | Proskelia Sas | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor |
| WO2010132127A1 (en) | 2009-05-13 | 2010-11-18 | Intra-Cellular Therapies, Inc. | Organic compounds |
| SG176010A1 (en) * | 2009-05-28 | 2011-12-29 | Novartis Ag | Substituted aminobutyric derivatives as neprilysin inhibitors |
| RS53664B1 (en) * | 2009-05-28 | 2015-04-30 | Novartis Ag | SUBSTITUTED AMINOPROPIONIC ACID DERIVATIVES AS NEPRILIZINE INHIBITORS |
| JO2967B1 (en) * | 2009-11-20 | 2016-03-15 | نوفارتس ايه جي | Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors |
| JP5790645B2 (ja) * | 2010-04-30 | 2015-10-07 | 日産化学工業株式会社 | ビスアミノフェニルアルキルウレアの新規な製造方法 |
| DK2956464T3 (en) | 2013-02-14 | 2018-07-16 | Novartis Ag | Substituted bisphenyl-butane phosphonic acid derivatives as NEP (neutral endopeptidase) inhibitors |
| KR20150119107A (ko) | 2013-02-14 | 2015-10-23 | 노파르티스 아게 | 개선된 생체내 효능을 갖는 nep 억제제로서의 치환된 비스페닐 부탄산 유도체 |
| JP6549040B2 (ja) | 2013-02-17 | 2019-07-24 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 新規使用 |
| ES2745819T3 (es) | 2014-08-07 | 2020-03-03 | Intra Cellular Therapies Inc | Derivados de imidazo[1,2-a]-pirazolo[4,3-e]-pirimidin-4-ona con actividad inhibidora de la PDE1 |
| WO2017172795A1 (en) | 2016-03-28 | 2017-10-05 | Intra-Cellular Therapies, Inc. | Novel compositions and methods |
| JP7401442B2 (ja) | 2018-01-31 | 2023-12-19 | イントラ-セルラー・セラピーズ・インコーポレイテッド | 新規使用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE53315B1 (en) * | 1980-12-18 | 1988-10-12 | Schering Corp | Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase |
| CY1406A (en) * | 1980-12-18 | 1988-04-22 | Schering Corp | Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase |
| DE3134933A1 (de) * | 1981-09-03 | 1983-03-31 | Hoechst Ag, 6230 Frankfurt | "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung" |
| JPS5823851A (ja) * | 1982-07-29 | 1983-02-12 | Mitsubishi Gas Chem Co Inc | 耐熱性樹脂組成物 |
| US4599198A (en) * | 1985-08-02 | 1986-07-08 | Pfizer Inc. | Intermediates in polypeptide synthesis |
| US4668769A (en) * | 1985-08-02 | 1987-05-26 | Hoover Dennis J | Oxa- and azahomocyclostatine polypeptides |
| US4757050A (en) * | 1985-12-23 | 1988-07-12 | E. R. Squibb Sons, Inc. | Ureido renin inhibitors |
| CA1297631C (en) * | 1985-12-23 | 1992-03-17 | Sesha I. Natarajan | Ureido renin inhibitors |
| DE3619508A1 (de) * | 1986-06-10 | 1987-12-17 | Merck Patent Gmbh | Aminosaeurederivate |
| JP2775690B2 (ja) * | 1989-08-22 | 1998-07-16 | 昭和シェル石油株式会社 | スリップ・レイヤー・シート |
| HU9301446D0 (en) * | 1990-11-19 | 1993-11-29 | Monsanto Co | Inhibitors or fetrovirus protease |
| US5475027A (en) * | 1990-11-19 | 1995-12-12 | G.D. Searle & Co. | Retroviral protease inhibitors |
| JPH0672985A (ja) * | 1992-08-28 | 1994-03-15 | Ono Pharmaceut Co Ltd | (チオ)ウレア誘導体 |
| JP3118738B2 (ja) * | 1992-12-22 | 2000-12-18 | 小野薬品工業株式会社 | (チオ)ウレア誘導体 |
-
1995
- 1995-11-01 CN CN95191137A patent/CN1055681C/zh not_active Expired - Fee Related
- 1995-11-01 AT AT95936083T patent/ATE190304T1/de not_active IP Right Cessation
- 1995-11-01 EP EP95936083A patent/EP0738711B1/en not_active Expired - Lifetime
- 1995-11-01 WO PCT/JP1995/002236 patent/WO1996014293A1/ja active IP Right Grant
- 1995-11-01 CA CA002180021A patent/CA2180021A1/en not_active Abandoned
- 1995-11-01 US US08/663,239 patent/US5891912A/en not_active Expired - Fee Related
- 1995-11-01 ES ES95936083T patent/ES2145929T3/es not_active Expired - Lifetime
- 1995-11-01 DE DE69515465T patent/DE69515465T2/de not_active Expired - Fee Related
- 1995-11-01 FI FI962751A patent/FI962751A7/fi not_active IP Right Cessation
- 1995-11-01 KR KR1019960703618A patent/KR100376150B1/ko not_active Expired - Fee Related
-
1996
- 1996-07-03 NO NO962810A patent/NO306944B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2180021A1 (en) | 1996-05-17 |
| ES2145929T3 (es) | 2000-07-16 |
| KR100376150B1 (ko) | 2003-11-01 |
| WO1996014293A1 (en) | 1996-05-17 |
| EP0738711B1 (en) | 2000-03-08 |
| ATE190304T1 (de) | 2000-03-15 |
| CN1055681C (zh) | 2000-08-23 |
| FI962751A0 (fi) | 1996-07-04 |
| DE69515465D1 (de) | 2000-04-13 |
| CN1138321A (zh) | 1996-12-18 |
| DE69515465T2 (de) | 2000-08-03 |
| EP0738711A4 (en) | 1998-09-30 |
| KR970702846A (ko) | 1997-06-10 |
| EP0738711A1 (en) | 1996-10-23 |
| NO962810L (no) | 1996-07-03 |
| FI962751L (fi) | 1996-07-04 |
| FI962751A7 (fi) | 1996-07-04 |
| US5891912A (en) | 1999-04-06 |
| NO962810D0 (no) | 1996-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |