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NO306944B1 - Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav - Google Patents

Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav

Info

Publication number
NO306944B1
NO306944B1 NO962810A NO962810A NO306944B1 NO 306944 B1 NO306944 B1 NO 306944B1 NO 962810 A NO962810 A NO 962810A NO 962810 A NO962810 A NO 962810A NO 306944 B1 NO306944 B1 NO 306944B1
Authority
NO
Norway
Prior art keywords
alkyl group
lower alkyl
substituted
derivatives
group
Prior art date
Application number
NO962810A
Other languages
English (en)
Other versions
NO962810L (no
NO962810D0 (no
Inventor
Yoichi Kawashima
Ken-Ichi Fujimura
Hiroshi Suhara
Nobuaki Miyawaki
Yuko Fujita
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of NO962810L publication Critical patent/NO962810L/no
Publication of NO962810D0 publication Critical patent/NO962810D0/no
Publication of NO306944B1 publication Critical patent/NO306944B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/10Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
NO962810A 1994-11-04 1996-07-03 Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav NO306944B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27095794 1994-11-04
PCT/JP1995/002236 WO1996014293A1 (en) 1994-11-04 1995-11-01 Novel 1,3-dialkylurea derivative having hydroxyl group

Publications (3)

Publication Number Publication Date
NO962810L NO962810L (no) 1996-07-03
NO962810D0 NO962810D0 (no) 1996-07-03
NO306944B1 true NO306944B1 (no) 2000-01-17

Family

ID=17493383

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962810A NO306944B1 (no) 1994-11-04 1996-07-03 Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav

Country Status (11)

Country Link
US (1) US5891912A (no)
EP (1) EP0738711B1 (no)
KR (1) KR100376150B1 (no)
CN (1) CN1055681C (no)
AT (1) ATE190304T1 (no)
CA (1) CA2180021A1 (no)
DE (1) DE69515465T2 (no)
ES (1) ES2145929T3 (no)
FI (1) FI962751A7 (no)
NO (1) NO306944B1 (no)
WO (1) WO1996014293A1 (no)

Families Citing this family (28)

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US7091311B2 (en) 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
US5985968A (en) * 1997-11-17 1999-11-16 Air Products And Chemicals, Inc. Surface tension reduction with N,N-dialkyl ureas
US6156784A (en) * 1997-12-18 2000-12-05 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as phosphotyrosine mimics
US6677360B2 (en) 1998-12-16 2004-01-13 Bayer Aktiengesellschaft Biphenyl and biphenyl-analogous compounds as integrin antagonists
US6420396B1 (en) 1998-12-16 2002-07-16 Beiersdorf Ag Biphenyl and biphenyl-analogous compounds as integrin antagonists
FR2820136A1 (fr) * 2001-01-26 2002-08-02 Aventis Pharma Sa Nouveaux derives de l'uree, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
US6842358B2 (en) * 2002-08-01 2005-01-11 Netlogic Microsystems, Inc. Content addressable memory with cascaded array
ES2462916T3 (es) 2002-09-18 2014-05-26 Janssen Pharmaceuticals, Inc. Métodos para aumentar la producción de células madre hematopoyéticas y plaquetas
DE10252650A1 (de) 2002-11-11 2004-05-27 Grünenthal GmbH Cyclohexyl-Harnstoff-Derivate
US7045653B2 (en) * 2002-12-23 2006-05-16 Pfizer, Inc. Pharmaceuticals
BRPI0409627A (pt) * 2003-04-21 2006-04-25 Elan Pharm Inc 2-hidróxi-3-diaminoalcanos de fenacila
ME00313B (me) * 2003-08-28 2011-05-10 Ortho Mcneil Pharm Inc Peptidi i jedinjenja koja se vežu za receptor
GB2425310B (en) * 2003-12-31 2008-04-16 Council Scient Ind Res N-aryloxypropanolyl-N' -phenethyl-urea
US6962945B2 (en) 2004-03-26 2005-11-08 Council Of Scientific And Industrial Research N-aryloxypropanolyl-N′-phenethyl-urea
FR2885129B1 (fr) 2005-04-29 2007-06-15 Proskelia Sas Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation.
ATE450262T1 (de) * 2005-11-25 2009-12-15 Galapagos Sas Harnstoff-derivate als calcium-rezeptor- modulatoren
GB0613674D0 (en) * 2006-07-10 2006-08-16 Proskelia Sas Derivatives of urea and related diamines, methods for their manufacture, and uses therefor
WO2010132127A1 (en) 2009-05-13 2010-11-18 Intra-Cellular Therapies, Inc. Organic compounds
SG176010A1 (en) * 2009-05-28 2011-12-29 Novartis Ag Substituted aminobutyric derivatives as neprilysin inhibitors
RS53664B1 (en) * 2009-05-28 2015-04-30 Novartis Ag SUBSTITUTED AMINOPROPIONIC ACID DERIVATIVES AS NEPRILIZINE INHIBITORS
JO2967B1 (en) * 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
JP5790645B2 (ja) * 2010-04-30 2015-10-07 日産化学工業株式会社 ビスアミノフェニルアルキルウレアの新規な製造方法
DK2956464T3 (en) 2013-02-14 2018-07-16 Novartis Ag Substituted bisphenyl-butane phosphonic acid derivatives as NEP (neutral endopeptidase) inhibitors
KR20150119107A (ko) 2013-02-14 2015-10-23 노파르티스 아게 개선된 생체내 효능을 갖는 nep 억제제로서의 치환된 비스페닐 부탄산 유도체
JP6549040B2 (ja) 2013-02-17 2019-07-24 イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. 新規使用
ES2745819T3 (es) 2014-08-07 2020-03-03 Intra Cellular Therapies Inc Derivados de imidazo[1,2-a]-pirazolo[4,3-e]-pirimidin-4-ona con actividad inhibidora de la PDE1
WO2017172795A1 (en) 2016-03-28 2017-10-05 Intra-Cellular Therapies, Inc. Novel compositions and methods
JP7401442B2 (ja) 2018-01-31 2023-12-19 イントラ-セルラー・セラピーズ・インコーポレイテッド 新規使用

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Publication number Priority date Publication date Assignee Title
IE53315B1 (en) * 1980-12-18 1988-10-12 Schering Corp Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
CY1406A (en) * 1980-12-18 1988-04-22 Schering Corp Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
DE3134933A1 (de) * 1981-09-03 1983-03-31 Hoechst Ag, 6230 Frankfurt "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung"
JPS5823851A (ja) * 1982-07-29 1983-02-12 Mitsubishi Gas Chem Co Inc 耐熱性樹脂組成物
US4599198A (en) * 1985-08-02 1986-07-08 Pfizer Inc. Intermediates in polypeptide synthesis
US4668769A (en) * 1985-08-02 1987-05-26 Hoover Dennis J Oxa- and azahomocyclostatine polypeptides
US4757050A (en) * 1985-12-23 1988-07-12 E. R. Squibb Sons, Inc. Ureido renin inhibitors
CA1297631C (en) * 1985-12-23 1992-03-17 Sesha I. Natarajan Ureido renin inhibitors
DE3619508A1 (de) * 1986-06-10 1987-12-17 Merck Patent Gmbh Aminosaeurederivate
JP2775690B2 (ja) * 1989-08-22 1998-07-16 昭和シェル石油株式会社 スリップ・レイヤー・シート
HU9301446D0 (en) * 1990-11-19 1993-11-29 Monsanto Co Inhibitors or fetrovirus protease
US5475027A (en) * 1990-11-19 1995-12-12 G.D. Searle & Co. Retroviral protease inhibitors
JPH0672985A (ja) * 1992-08-28 1994-03-15 Ono Pharmaceut Co Ltd (チオ)ウレア誘導体
JP3118738B2 (ja) * 1992-12-22 2000-12-18 小野薬品工業株式会社 (チオ)ウレア誘導体

Also Published As

Publication number Publication date
CA2180021A1 (en) 1996-05-17
ES2145929T3 (es) 2000-07-16
KR100376150B1 (ko) 2003-11-01
WO1996014293A1 (en) 1996-05-17
EP0738711B1 (en) 2000-03-08
ATE190304T1 (de) 2000-03-15
CN1055681C (zh) 2000-08-23
FI962751A0 (fi) 1996-07-04
DE69515465D1 (de) 2000-04-13
CN1138321A (zh) 1996-12-18
DE69515465T2 (de) 2000-08-03
EP0738711A4 (en) 1998-09-30
KR970702846A (ko) 1997-06-10
EP0738711A1 (en) 1996-10-23
NO962810L (no) 1996-07-03
FI962751L (fi) 1996-07-04
FI962751A7 (fi) 1996-07-04
US5891912A (en) 1999-04-06
NO962810D0 (no) 1996-07-03

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