ATE162555T1 - Verfahren zum screenen von substanzen mit modulierender wirkung auf einen interleukin-5- rezeptor-abhängigen zellulären signalübertragungsweg - Google Patents
Verfahren zum screenen von substanzen mit modulierender wirkung auf einen interleukin-5- rezeptor-abhängigen zellulären signalübertragungswegInfo
- Publication number
- ATE162555T1 ATE162555T1 AT94918807T AT94918807T ATE162555T1 AT E162555 T1 ATE162555 T1 AT E162555T1 AT 94918807 T AT94918807 T AT 94918807T AT 94918807 T AT94918807 T AT 94918807T AT E162555 T1 ATE162555 T1 AT E162555T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor
- signal transmission
- interleukine
- pct
- interleukin
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 230000008054 signal transmission Effects 0.000 title abstract 3
- 230000000694 effects Effects 0.000 title abstract 2
- 238000012216 screening Methods 0.000 title abstract 2
- 102000000743 Interleukin-5 Human genes 0.000 title 1
- 108010002616 Interleukin-5 Proteins 0.000 title 1
- 230000001413 cellular effect Effects 0.000 title 1
- 229940100602 interleukin-5 Drugs 0.000 title 1
- 230000037361 pathway Effects 0.000 title 1
- 230000001419 dependent effect Effects 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 108700008625 Reporter Genes Proteins 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4317577A DE4317577A1 (de) | 1993-05-27 | 1993-05-27 | Verfahren zum Screenen von Substanzen mit modulierender Wirkung auf einen Interleukin-5-Rezeptor-abhängigen zellulären Signalübertragungsweg |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE162555T1 true ATE162555T1 (de) | 1998-02-15 |
Family
ID=6488996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94918807T ATE162555T1 (de) | 1993-05-27 | 1994-05-27 | Verfahren zum screenen von substanzen mit modulierender wirkung auf einen interleukin-5- rezeptor-abhängigen zellulären signalübertragungsweg |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5922549A (de) |
| EP (1) | EP0701628B1 (de) |
| JP (1) | JPH08510643A (de) |
| KR (1) | KR100318188B1 (de) |
| CN (1) | CN1125467A (de) |
| AT (1) | ATE162555T1 (de) |
| AU (1) | AU691816B2 (de) |
| CA (1) | CA2163549A1 (de) |
| DE (2) | DE4317577A1 (de) |
| DK (1) | DK0701628T3 (de) |
| ES (1) | ES2113109T3 (de) |
| FI (1) | FI111016B (de) |
| HU (1) | HU220345B (de) |
| NO (1) | NO316027B1 (de) |
| NZ (1) | NZ291131A (de) |
| RU (1) | RU2139936C1 (de) |
| WO (1) | WO1994028170A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9405350D0 (en) * | 1994-03-18 | 1994-05-04 | Sandoz Ltd | Organic compounds |
| US5668110A (en) * | 1995-06-07 | 1997-09-16 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
| US5677280A (en) * | 1995-06-07 | 1997-10-14 | Glaxo Group Limited | Peptides and compounds that bind to the IL-5 receptor |
| US5654276A (en) * | 1995-06-07 | 1997-08-05 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
| US5683983A (en) * | 1995-06-07 | 1997-11-04 | Glaxo Group Limited | Peptides and compounds that bind to the IL-5 receptor |
| US7109299B1 (en) | 1999-12-16 | 2006-09-19 | Affymax, Inc. | Peptides and compounds that bind to the IL-5 receptor |
| RU2181773C2 (ru) * | 2000-03-16 | 2002-04-27 | Научно-исследовательский институт вирусологии им. Д.И. Ивановского РАМН | Способ определения цитокинового статуса человека на генетическом уровне |
| AU2001296607A1 (en) * | 2000-10-03 | 2002-04-15 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | High efficiency regulatable gene expression system |
| RU2215292C2 (ru) * | 2000-12-28 | 2003-10-27 | Общество С Ограниченной Ответственностью "Ферон" | Способ выбора терапии при герпесе |
| US20040170614A1 (en) * | 2002-10-30 | 2004-09-02 | Gail Bishop | Somatic cell gene targeting vectors and methods of use thereof |
| US20040209246A1 (en) * | 2003-04-15 | 2004-10-21 | Agouron Pharmaceuticals, Inc. | Dual reporter/dye reduction methodology for evaluating antiviral and cytotoxicity of hepatitis C virus inhibitors |
| US20050112551A1 (en) * | 2003-11-24 | 2005-05-26 | Agouron Pharmaceuticals, Inc. | Dual assay for evaluating activity and cytotoxicity of compounds in the same population of cells |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5071773A (en) * | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
| US5401629A (en) * | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| US5453491A (en) * | 1990-09-11 | 1995-09-26 | Kiyoshi Takatsu | Murine interleukin-5 receptor |
| AU1469292A (en) * | 1991-01-18 | 1992-08-27 | Oncogene Science, Inc. | Methods of transcriptionally modulating expression of growth factor genes and growth factor receptor genes |
| WO1993007294A1 (en) * | 1991-10-01 | 1993-04-15 | The United States Of America, Represented By The Secretary, Department Of Health And Human Service | A method of identifying ligands and antagonists of ligands |
-
1993
- 1993-05-27 DE DE4317577A patent/DE4317577A1/de not_active Withdrawn
-
1994
- 1994-05-27 AT AT94918807T patent/ATE162555T1/de not_active IP Right Cessation
- 1994-05-27 AU AU69977/94A patent/AU691816B2/en not_active Ceased
- 1994-05-27 DE DE59405120T patent/DE59405120D1/de not_active Expired - Fee Related
- 1994-05-27 JP JP7500238A patent/JPH08510643A/ja not_active Ceased
- 1994-05-27 CA CA002163549A patent/CA2163549A1/en not_active Abandoned
- 1994-05-27 HU HU9503363A patent/HU220345B/hu not_active IP Right Cessation
- 1994-05-27 WO PCT/EP1994/001735 patent/WO1994028170A1/de active IP Right Grant
- 1994-05-27 NZ NZ291131A patent/NZ291131A/en unknown
- 1994-05-27 RU RU95122776/13A patent/RU2139936C1/ru not_active IP Right Cessation
- 1994-05-27 CN CN94192453A patent/CN1125467A/zh active Pending
- 1994-05-27 EP EP94918807A patent/EP0701628B1/de not_active Expired - Lifetime
- 1994-05-27 US US08/553,304 patent/US5922549A/en not_active Expired - Lifetime
- 1994-05-27 ES ES94918807T patent/ES2113109T3/es not_active Expired - Lifetime
- 1994-05-27 DK DK94918807T patent/DK0701628T3/da active
- 1994-05-27 KR KR1019950705282A patent/KR100318188B1/ko not_active Expired - Fee Related
-
1995
- 1995-11-24 NO NO19954781A patent/NO316027B1/no not_active IP Right Cessation
- 1995-11-27 FI FI955700A patent/FI111016B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO954781D0 (no) | 1995-11-24 |
| DK0701628T3 (da) | 1998-09-21 |
| EP0701628A1 (de) | 1996-03-20 |
| NZ291131A (en) | 1996-10-28 |
| KR100318188B1 (ko) | 2002-06-20 |
| WO1994028170A1 (de) | 1994-12-08 |
| EP0701628B1 (de) | 1998-01-21 |
| AU6997794A (en) | 1994-12-20 |
| RU2139936C1 (ru) | 1999-10-20 |
| US5922549A (en) | 1999-07-13 |
| CA2163549A1 (en) | 1994-12-08 |
| AU691816B2 (en) | 1998-05-28 |
| DE4317577A1 (de) | 1994-12-01 |
| HUT73742A (en) | 1996-09-30 |
| CN1125467A (zh) | 1996-06-26 |
| HU9503363D0 (en) | 1996-01-29 |
| KR960702532A (ko) | 1996-04-27 |
| ES2113109T3 (es) | 1998-04-16 |
| FI955700L (fi) | 1995-11-27 |
| DE59405120D1 (de) | 1998-02-26 |
| NO954781L (no) | 1996-01-23 |
| FI111016B (fi) | 2003-05-15 |
| HU220345B (hu) | 2001-12-28 |
| NO316027B1 (no) | 2003-12-01 |
| FI955700A0 (fi) | 1995-11-27 |
| JPH08510643A (ja) | 1996-11-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE59209288D1 (de) | Verfahren zum screenen von substanzen mit modulierender wirkung auf einen rezeptorabhängigen zellulären signalübertragungsweg | |
| ATE162555T1 (de) | Verfahren zum screenen von substanzen mit modulierender wirkung auf einen interleukin-5- rezeptor-abhängigen zellulären signalübertragungsweg | |
| Ecker et al. | Pseudo—half-knot formation with RNA | |
| ATE86738T1 (de) | Verfahren zur identifizierung von liganden an ort und stelle. | |
| DK0414475T3 (da) | Fremgangsmåder til dyrkning af HCV i B- eller T-lymfocyt-cellelinier | |
| ATE155885T1 (de) | Verfahren zur markierung einer flüssigkeit | |
| ATE36413T1 (de) | Testverfahren unter verwendung von enzymen als markierungssubstanzen. | |
| ZA877719B (en) | Immunoassay based on two enzyme inhibition system | |
| ATE7335T1 (de) | Vorrichtung zum nachweis von strom in hochspannungsuebertragungsleitungen unter verwendung von lichtleitfasern zur uebertragung digitaler information. | |
| ATE377073T1 (de) | Modulatoren der funktion des fas/ap01 rezeptors | |
| DE69518450D1 (de) | Test zum Nachweis von Proteinen in einer biologischen Probe | |
| ATE35693T1 (de) | Verfahren und vorrichtung zur identifizierung von mikroorganismen. | |
| ATE366120T1 (de) | Hocheffizientes gewebespezifisches system zur bereitstellung von verbindungen unter verwendung eines streptavidin-protein a fusionsproteins | |
| Owe‐Larsson et al. | Perturbation of the synaptic release machinery in hippocampal neurons by overexpression of SNAP‐25 with the Semliki Forest virus vector | |
| Europe-Finner et al. | Inhibition of aggregation in Dictyostelium by EGTA-induced depletion of calcium | |
| Scheres et al. | “Reverse” differential staining of sister chromatids | |
| DE69919684D1 (de) | Verwendung von isolierten domänen des type-iv-kollagens zur änderung der zell- und gewebewechselwirkung | |
| DE69033352D1 (de) | Competitives enzym-testverfahren zum nachweis von phosphothioaten | |
| Parry et al. | The uncoupled regulation of fibronectin and collagen synthesis in Rous sarcoma virus transformed avian tendon cells. | |
| DE69610483D1 (de) | In kunstlisches Rekombinantes Substrat rAGG-1 und nativem Aggrecan zum Studium der proteolytischen Wirkung von 'Aggrecanase' in Zellkultursystemen | |
| DE69432422D1 (de) | Methoden zum aufspüren von anti-östrogenverbindungen | |
| ATE41529T1 (de) | Verfahren zur immunologischen bestimmung einer substanz in einer fluessigen probe. | |
| Rübsamen et al. | Identification of a calcium-binding subunit of the acetylcholine receptor | |
| BR9708256A (pt) | Processo para identificar genes com expresão específica ao síto ou de síto preferido em células de marcacção específicas presentes em um ambiente de células diferente ou não daquele de sua origem e uso do mesmo | |
| EP1019543B1 (de) | Verfahren zum identifizieren einer nukleinsäure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |