ATE289204T1 - Arzneimittel zur vorbeugung / behandlung / inhibierung des fortschritts für einfache oder preproliferative retinopathie - Google Patents

Arzneimittel zur vorbeugung / behandlung / inhibierung des fortschritts für einfache oder preproliferative retinopathie

Info

Publication number: ATE289204T1
Authority: AT; Austria
Prior art keywords: treating; preventing; inhibiting; progress; medicinal products
Prior art date: 1999-04-28

Application number

AT00921056T

Other languages

English (en)

Inventor

Shizue Nakagawa

Yasutaka Nagisa

Hitoshi Ikeda

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-28

Filing date

2000-04-27

Publication date

2005-03-15

2000-04-27 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2005-03-15 Application granted granted Critical

2005-03-15 Publication of ATE289204T1 publication Critical patent/ATE289204T1/de

Links

208000017442 Retinal disease Diseases 0.000 title abstract 2
206010038923 Retinopathy Diseases 0.000 title abstract 2
230000002401 inhibitory effect Effects 0.000 title abstract 2
229940126601 medicinal product Drugs 0.000 title 1
102000005862 Angiotensin II Human genes 0.000 abstract 1
101800000733 Angiotensin-2 Proteins 0.000 abstract 1
206010012689 Diabetic retinopathy Diseases 0.000 abstract 1
CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
229950006323 angiotensin ii Drugs 0.000 abstract 1
230000003042 antagnostic effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Cardiology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT00921056T 1999-04-28 2000-04-27 Arzneimittel zur vorbeugung / behandlung / inhibierung des fortschritts für einfache oder preproliferative retinopathie ATE289204T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP12149899		1999-04-28
PCT/JP2000/002766 WO2000066161A1 (fr)	1999-04-28	2000-04-27	Preventifs / remedes / inhibiteurs de progression pour retinopathie simplex ou retinopathie preproliferante

Publications (1)

Publication Number	Publication Date
ATE289204T1 true ATE289204T1 (de)	2005-03-15

Family

ID=14812676

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00921056T ATE289204T1 (de)	1999-04-28	2000-04-27	Arzneimittel zur vorbeugung / behandlung / inhibierung des fortschritts für einfache oder preproliferative retinopathie

Country Status (23)

Country	Link
US (2)	US7064141B1 (de)
EP (1)	EP1197223B1 (de)
KR (1)	KR100865059B1 (de)
CN (1)	CN1172719C (de)
AT (1)	ATE289204T1 (de)
AU (1)	AU774799B2 (de)
BR (1)	BR0010084A (de)
CA (1)	CA2371554C (de)
CZ (1)	CZ301913B6 (de)
DE (1)	DE60018186T2 (de)
DK (1)	DK1197223T3 (de)
ES (1)	ES2233362T3 (de)
HU (1)	HU226948B1 (de)
MX (1)	MXPA01010923A (de)
NO (1)	NO327446B1 (de)
NZ (1)	NZ514855A (de)
PL (1)	PL196895B1 (de)
PT (1)	PT1197223E (de)
RU (1)	RU2239454C2 (de)
SI (1)	SI1197223T1 (de)
SK (1)	SK286859B6 (de)
WO (1)	WO2000066161A1 (de)
ZA (1)	ZA200108527B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2468827A1 (en) *	2001-12-03	2003-06-12	Takeda Chemical Industries, Ltd.	Insulin resistance improving agents
JP4484427B2 (ja) *	2001-12-03	2010-06-16	武田薬品工業株式会社	インスリン抵抗性改善剤
TW200304812A (en) *	2002-03-08	2003-10-16	Sankyo Co	An eye drop containing a tetrazole derivative
US8980870B2 (en)	2002-09-24	2015-03-17	Boehringer Ingelheim International Gmbh	Solid telmisartan pharmaceutical formulations
DE10335027A1 (de) *	2003-07-31	2005-02-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung von Angiotensin II Rezeptor Antagonisten
EP1614428A4 (de) *	2003-04-15	2010-01-06	Sankyo Co	Arzneimittel zur vorbeugung oder behandlung angiogener augenerkrankungen
US20050038093A1 (en) *	2003-05-02	2005-02-17	Boehringer Ingelheim International Gmbh	Treating diabetic retinopathy with angiotensin II receptor blockers
CA2576827A1 (en)	2004-08-31	2006-03-09	Newsouth Innovations Pty Limited	Vegf inhibition
CN103083318A (zh) *	2004-11-05	2013-05-08	贝林格尔.英格海姆国际有限公司	包含替米沙坦和氨氯地平的双层片剂
PT1872783E (pt) *	2005-04-21	2012-01-16	Santen Pharmaceutical Co Ltd	Agente terapêutico para distúrbio queratoconjuntivo
RU2423127C2 (ru) *	2005-12-06	2011-07-10	Сантен Фармасьютикал Ко., Лтд.	Терапевтическое средство против роговично-конъюнктивального нарушения
TWI415634B (zh) *	2007-03-28	2013-11-21	Takeda Pharmaceutical	固態醫藥組成物

Family Cites Families (21)

* Cited by examiner, † Cited by third party
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GB9027211D0 (en) *	1990-12-14	1991-02-06	Smithkline Beecham Plc	Medicaments
US5614519A (en)	1991-02-06	1997-03-25	Karl Thomae Gmbh	(1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists
DE4201554A1 (de)	1992-01-22	1993-07-29	Thomae Gmbh Dr K	Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
GB9110635D0 (en)	1991-05-16	1991-07-03	Glaxo Group Ltd	Chemical compounds
ZA931063B (en)	1992-02-17	1993-09-23	Ciba Geigy	Treatment of glaucoma.
GB9223860D0 (en) *	1992-11-13	1993-01-06	Glaxo Group Ltd	Chemical compounds
CZ154994A3 (en) *	1993-07-02	1995-09-13	Senju Pharma Co	Visual hypotensive agent
JPH0789957A (ja)	1993-09-22	1995-04-04	Nissan Chem Ind Ltd	ビフェニルメチルアミン誘導体
ATE300287T1 (de)	1994-02-08	2005-08-15	Novartis Pharma Gmbh	Behandlung von normaldruckglaukom mit valsartan
JPH09210183A (ja) *	1996-01-31	1997-08-12	Suzuki Motor Corp	動力伝達装置
CA2250395C (en) *	1996-03-29	2005-09-06	Smithkline Beecham Corporation	Eprosartan dihydrate and a process for its production and formulation
EP1192951A3 (de) *	1996-04-05	2004-04-21	Takeda Chemical Industries, Ltd.	Pharmazeutische Kombinationen welche Angiotensin-II Antagonistich wirkende Bestandteilen mit andere Bestandteilen enthalten
TW416953B (en)	1996-09-25	2001-01-01	Takeda Chemical Industries Ltd	Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use
EP0855392A3 (de) *	1997-01-22	2000-01-05	Hoechst Aktiengesellschaft	Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
JP4475685B2 (ja) *	1997-06-27	2010-06-09	スミスクライン・ビーチャム・コーポレイション	エプロサルタン・一水和物
IT1292437B1 (it) *	1997-06-30	1999-02-08	Zambon Spa	Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti
CZ296274B6 (cs) *	1997-08-06	2006-02-15	Smithkline Beecham Corporation	Neutralizacní komplex arginyl-eprosartan, zpusob jeho prípravy a prostredek
KR20010086245A (ko)	1998-03-04	2001-09-10	다케다 야쿠힌 고교 가부시키가이샤	Ａⅱ 길항제용 서방성 제제, 그것의 제조 및 용도
SK285863B6 (sk)	1998-07-10	2007-10-04	Novartis Ag	Kombinovaná farmaceutická kompozícia obsahujúca AT1-antagonistu valsartan a amlodipín
FR2783422A1 (fr)	1998-09-21	2000-03-24	Sanofi Sa	Composition pharmaceutique contenant un antagoniste des recepteurs at1 de l'angiotensine ii et un antiagregant plaquettaire
JP2000159671A (ja)	1998-12-01	2000-06-13	Takeda Chem Ind Ltd	血管新生阻害剤

2000
- 2000-04-27 AU AU41434/00A patent/AU774799B2/en not_active Ceased
- 2000-04-27 ES ES00921056T patent/ES2233362T3/es not_active Expired - Lifetime
- 2000-04-27 PL PL350554A patent/PL196895B1/pl not_active IP Right Cessation
- 2000-04-27 PT PT00921056T patent/PT1197223E/pt unknown
- 2000-04-27 WO PCT/JP2000/002766 patent/WO2000066161A1/ja active IP Right Grant
- 2000-04-27 DE DE60018186T patent/DE60018186T2/de not_active Expired - Lifetime
- 2000-04-27 US US09/958,740 patent/US7064141B1/en not_active Expired - Fee Related
- 2000-04-27 RU RU2001132073/15A patent/RU2239454C2/ru not_active IP Right Cessation
- 2000-04-27 CA CA002371554A patent/CA2371554C/en not_active Expired - Fee Related
- 2000-04-27 KR KR1020017013765A patent/KR100865059B1/ko not_active Expired - Fee Related
- 2000-04-27 SK SK1545-2001A patent/SK286859B6/sk not_active IP Right Cessation
- 2000-04-27 CZ CZ20013804A patent/CZ301913B6/cs not_active IP Right Cessation
- 2000-04-27 EP EP00921056A patent/EP1197223B1/de not_active Expired - Lifetime
- 2000-04-27 MX MXPA01010923A patent/MXPA01010923A/es active IP Right Grant
- 2000-04-27 SI SI200030651T patent/SI1197223T1/xx unknown
- 2000-04-27 DK DK00921056T patent/DK1197223T3/da active
- 2000-04-27 AT AT00921056T patent/ATE289204T1/de not_active IP Right Cessation
- 2000-04-27 BR BR0010084-6A patent/BR0010084A/pt not_active Application Discontinuation
- 2000-04-27 CN CNB008067783A patent/CN1172719C/zh not_active Expired - Fee Related
- 2000-04-27 HU HU0200890A patent/HU226948B1/hu not_active IP Right Cessation
- 2000-04-27 NZ NZ514855A patent/NZ514855A/xx not_active IP Right Cessation
2001
- 2001-10-17 ZA ZA200108527A patent/ZA200108527B/en unknown
- 2001-10-26 NO NO20015257A patent/NO327446B1/no not_active IP Right Cessation
2006
- 2006-04-19 US US11/406,345 patent/US20060189669A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN1172719C (zh)	2004-10-27
EP1197223A1 (de)	2002-04-17
PL350554A1 (en)	2002-12-16
NO327446B1 (no)	2009-06-29
NO20015257L (no)	2001-10-26
HU226948B1 (en)	2010-03-29
KR100865059B1 (ko)	2008-10-23
NO20015257D0 (no)	2001-10-26
DE60018186D1 (de)	2005-03-24
RU2239454C2 (ru)	2004-11-10
SK15452001A3 (sk)	2002-04-04
SK286859B6 (sk)	2009-06-05
ZA200108527B (en)	2002-10-17
WO2000066161A1 (fr)	2000-11-09
DE60018186T2 (de)	2005-12-29
ES2233362T3 (es)	2005-06-16
EP1197223B1 (de)	2005-02-16
PT1197223E (pt)	2005-04-29
MXPA01010923A (es)	2002-06-21
SI1197223T1 (de)	2005-08-31
CZ301913B6 (cs)	2010-07-28
HUP0200890A2 (hu)	2002-11-28
DK1197223T3 (da)	2005-05-30
AU4143400A (en)	2000-11-17
EP1197223A4 (de)	2003-10-29
CZ20013804A3 (cs)	2002-04-17
HUP0200890A3 (en)	2002-12-28
US20060189669A1 (en)	2006-08-24
KR20020015315A (ko)	2002-02-27
CA2371554C (en)	2009-06-09
PL196895B1 (pl)	2008-02-29
US7064141B1 (en)	2006-06-20
CA2371554A1 (en)	2000-11-09
CN1348385A (zh)	2002-05-08
AU774799B2 (en)	2004-07-08
BR0010084A (pt)	2002-01-15
NZ514855A (en)	2004-01-30

Publication	Publication Date	Title
BR0109703A (pt)	2003-02-04	Derivados de piperazina
TR200000129T2 (tr)	2000-07-21	Yepyeni spiroazabisiklik heterosiklik bileşikler.
DE50311898D1 (de)	2009-10-22	Fredericamycin-derivate als arzneimittel zur tumorbehandlung
ATE248837T1 (de)	2003-09-15	Chinuclidin-acrylamide
ATE538794T1 (de)	2012-01-15	Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
GB0225475D0 (en)	2002-12-11	Therapeutic agents
DE50310516D1 (de)	2008-10-30	Fredericamycin-derivate
GB0318447D0 (en)	2003-09-10	Therapeutic agents
WO2003080582A3 (de)	2004-12-09	Fredericamycin-derivate
IL171977A (en)	2010-12-30	Cyclic sulfonamide for inhibition of gamma-secretase, process for its preparation and a pharmaceutical composition comprising the same
TNSN04203A1 (en)	2007-03-12	Benzoxazinone-derived compounds, their preparation and use as medicaments
GB0222514D0 (en)	2002-11-06	Organic compounds
BR0316723A (pt)	2005-10-18	Derivados de anilinopirazol úteis para o tratamento de diabetes
GEP20094638B (en)	2009-03-10	Benzimidazolone carboxylic acid derivatives
ATE289204T1 (de)	2005-03-15	Arzneimittel zur vorbeugung / behandlung / inhibierung des fortschritts für einfache oder preproliferative retinopathie
ECSP055809A (es)	2005-08-11	Inhibidores 4-oxo-1-(3-fenil sustituido)-1,4-dihidro-1,8-naftiridina-3-carboxamida de la fosfodiesterasa-4
PE20030061A1 (es)	2003-02-08	1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
ES2164109T3 (es)	2002-02-16	Derivados de n-(3-piperidinilcarbonil)-beta-alanina como antagonistas de paf.
NO20000446D0 (no)	2000-01-28	Anvendelse av fysiologisk akseptable vanadiumforbindelser, salter og komplekser
SG162614A1 (en)	2010-07-29	Bicyclic 6-alkylidene-penems as beta-lactamases inhibitors
DE69925270D1 (de)	2005-06-16	Mittel zur linderung von juckreiz, enthaltend pgd2- antagonisten
UY27451A1 (es)	2003-04-30	2,5-diamidoindoles sustituidos y su utilización
BR0211223A (pt)	2004-08-10	Derivados de 4-aminociclohexanol substituìdos
MY136965A (en)	2008-12-31	1,4-disubstituted piperidine compounds, their preparation and use as medicaments
MXPA05007515A (es)	2006-01-27	Metodo para la produccion de derivados de acil-fenil-urea sustituidos por amino-carbonilo y el uso de los mismos.

Legal Events

Date	Code	Title	Description
2005-10-15	UEP	Publication of translation of european patent specification	Ref document number: 1197223 Country of ref document: EP
2012-01-15	REN	Ceased due to non-payment of the annual fee

Date

Code

Title

Description

2005-10-15

UEP

Publication of translation of european patent specification

Ref document number: 1197223

Country of ref document: EP

2012-01-15

REN

Ceased due to non-payment of the annual fee