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ATE297219T1 - Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome) - Google Patents

Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome)

Info

Publication number
ATE297219T1
ATE297219T1 AT98902757T AT98902757T ATE297219T1 AT E297219 T1 ATE297219 T1 AT E297219T1 AT 98902757 T AT98902757 T AT 98902757T AT 98902757 T AT98902757 T AT 98902757T AT E297219 T1 ATE297219 T1 AT E297219T1
Authority
AT
Austria
Prior art keywords
myelomas
medicinal
antibodies
exclusively
lymphocytic tumors
Prior art date
Application number
AT98902757T
Other languages
English (en)
Inventor
Yasuo Koishihara
Yasushi Yoshimura
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE297219T1 publication Critical patent/ATE297219T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT98902757T 1997-02-12 1998-02-12 Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome) ATE297219T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4141097 1997-02-12
PCT/JP1998/000568 WO1998035698A1 (fr) 1997-02-12 1998-02-12 Remedes contre les tumeurs lymphocitaires

Publications (1)

Publication Number Publication Date
ATE297219T1 true ATE297219T1 (de) 2005-06-15

Family

ID=12607597

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98902757T ATE297219T1 (de) 1997-02-12 1998-02-12 Antikörper als arzneimittel gegen lymphocytische tumore (ausschliesslich myelome)

Country Status (19)

Country Link
US (2) US6503510B2 (de)
EP (1) EP0997152B1 (de)
KR (2) KR20000070989A (de)
CN (1) CN1191855C (de)
AT (1) ATE297219T1 (de)
AU (1) AU724133B2 (de)
BR (1) BR9811094A (de)
CA (1) CA2280875C (de)
DE (1) DE69830492T2 (de)
ES (1) ES2241114T3 (de)
HU (1) HUP0001136A3 (de)
IL (1) IL131381A0 (de)
NO (1) NO993866L (de)
PL (1) PL190065B1 (de)
RU (1) RU2177805C2 (de)
SK (1) SK110099A3 (de)
TR (1) TR199901949T2 (de)
UA (1) UA65561C2 (de)
WO (1) WO1998035698A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW474991B (en) * 1993-10-15 2002-02-01 Toshio Hirano Membrane protein polypeptide having function of pre-B cell proliferation and the encoded gene thereof
UA76934C2 (en) * 1996-10-04 2006-10-16 Chugai Pharmaceutical Co Ltd Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
ATE462975T1 (de) * 1998-02-25 2010-04-15 Chugai Pharmaceutical Co Ltd Verfahren zum immunochemischen testen des anti- hm1.24-antikörpers
CN1370076A (zh) 1999-08-23 2002-09-18 中外制药株式会社 Hm1.24抗原的表达增强剂
JP4450555B2 (ja) * 2000-12-28 2010-04-14 協和発酵キリン株式会社 新規モノクローナル抗体
JP3986439B2 (ja) * 2001-02-07 2007-10-03 中外製薬株式会社 造血器腫瘍の治療剤
US7332289B2 (en) 2001-03-09 2008-02-19 Chugai Seiyaku Kabushiki Kaisha Method of purifying protein
US20050226869A1 (en) * 2001-10-19 2005-10-13 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
US7888478B2 (en) * 2002-09-11 2011-02-15 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
US7858330B2 (en) 2001-10-19 2010-12-28 Genentech, Inc. Compositions and methods for the treatment of tumor of hematopoietic origin
DK1475101T3 (da) * 2002-02-14 2011-01-10 Chugai Pharmaceutical Co Ltd Antistof-holdige farmaceutiske opløsninger
US20030223998A1 (en) * 2002-02-27 2003-12-04 Lamb Lawrence S. Targeted immunotherapy of acute lymphoblastic leukemia (ALL)
US20080219974A1 (en) * 2002-03-01 2008-09-11 Bernett Matthew J Optimized antibodies that target hm1.24
JP4462964B2 (ja) * 2003-03-10 2010-05-12 第一三共株式会社 癌特異的抗原を標的とした抗体
JPWO2005014651A1 (ja) * 2003-08-11 2006-11-24 中外製薬株式会社 糖鎖改変抗ｈｍ１．２４抗体
US8603481B2 (en) 2003-10-10 2013-12-10 Chugai Seiyaku Kabushiki Kaisha Therapeutic agents for solid tumors
MX2007004593A (es) * 2004-10-26 2007-06-22 Chugai Pharmaceutical Co Ltd Anticuerpo anti-glipican 3 que tiene cadena de azucar modificada.
US8329186B2 (en) 2004-12-20 2012-12-11 Isu Abxis Co., Ltd Treatment of inflammation using BST2 inhibitor
US20080299128A1 (en) 2006-06-20 2008-12-04 Myung Kim Effect of Bst2 on inflammation
CN1865275B (zh) * 2005-05-17 2011-06-15 长春华普生物技术有限公司 对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸
EP1910419A2 (de) * 2005-06-20 2008-04-16 Genentech, Inc. Zusammensetzungen und verfahren für dietumor-diagnose und behandlung
JP5562031B2 (ja) * 2006-09-18 2014-07-30 ゼンコー・インコーポレイテッド Ｈｍ１．２４を標的とする最適化抗体
EP2210939A4 (de) 2007-10-16 2012-08-08 Sbi Biotech Co Ltd Anti-bst2-antikörper
TWI516501B (zh) 2008-09-12 2016-01-11 禮納特神經系統科學公司 Ｐｃｓｋ９拮抗劑類
US9123149B2 (en) * 2013-03-15 2015-09-01 Columbia Insurance Company Expert color system for color selection with color harmony and color emotion intelligence
CN107619443B (zh) * 2016-07-14 2020-08-14 深圳宾德生物技术有限公司 抗人和鼠cd317的单克隆抗体及其制备方法和应用
CN109748964B (zh) * 2017-11-01 2020-11-17 深圳宾德生物技术有限公司 CD317单链抗体317scFv、其编码序列及制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650150A (en) * 1990-11-09 1997-07-22 Gillies; Stephen D. Recombinant antibody cytokine fusion proteins
WO1992019759A1 (en) * 1991-04-25 1992-11-12 Chugai Seiyaku Kabushiki Kaisha Reconstituted human antibody against human interleukin 6 receptor
TW474991B (en) * 1993-10-15 2002-02-01 Toshio Hirano Membrane protein polypeptide having function of pre-B cell proliferation and the encoded gene thereof
UA76934C2 (en) * 1996-10-04 2006-10-16 Chugai Pharmaceutical Co Ltd Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
KR100370744B1 (ko) * 1997-02-28 2003-02-05 츄가이 세이야꾸 가부시키가이샤 임파구의 활성화 억제제
JP3992298B2 (ja) * 1997-10-03 2007-10-17 中外製薬株式会社 天然ヒト型化抗体
CA2308007C (en) * 1997-10-14 2011-05-17 Chugai Seiyaku Kabushiki Kaisha Enhancer for antibody to lymphocytic tumors

Also Published As

Publication number Publication date
CA2280875A1 (en) 1998-08-20
EP0997152A4 (de) 2001-04-18
PL335140A1 (en) 2000-04-10
TR199901949T2 (xx) 2000-01-21
HK1026368A1 (en) 2000-12-15
ES2241114T3 (es) 2005-10-16
KR20000070989A (ko) 2000-11-25
KR100655979B1 (ko) 2006-12-08
HUP0001136A2 (hu) 2000-08-28
SK110099A3 (en) 2000-08-14
AU5956398A (en) 1998-09-08
RU2177805C2 (ru) 2002-01-10
UA65561A (en) 2000-08-15
KR20030097614A (ko) 2003-12-31
US20030113334A1 (en) 2003-06-19
BR9811094A (pt) 2000-07-18
HUP0001136A3 (en) 2002-02-28
CN1191855C (zh) 2005-03-09
CA2280875C (en) 2005-07-05
EP0997152B1 (de) 2005-06-08
CN1250381A (zh) 2000-04-12
PL190065B1 (pl) 2005-10-31
NO993866D0 (no) 1999-08-11
WO1998035698A1 (fr) 1998-08-20
UA65561C2 (uk) 2004-04-15
DE69830492D1 (de) 2005-07-14
AU724133B2 (en) 2000-09-14
IL131381A0 (en) 2001-01-28
EP0997152A1 (de) 2000-05-03
US20020037288A1 (en) 2002-03-28
NO993866L (no) 1999-10-11
DE69830492T2 (de) 2006-03-16
US6503510B2 (en) 2003-01-07

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