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BRPI0613123B8 - enxerto sem células - Google Patents

enxerto sem células

Info

Publication number
BRPI0613123B8
BRPI0613123B8 BRPI0613123A BRPI0613123A BRPI0613123B8 BR PI0613123 B8 BRPI0613123 B8 BR PI0613123B8 BR PI0613123 A BRPI0613123 A BR PI0613123A BR PI0613123 A BRPI0613123 A BR PI0613123A BR PI0613123 B8 BRPI0613123 B8 BR PI0613123B8
Authority
BR
Brazil
Prior art keywords
graft
serum
cell
matrix
gel
Prior art date
Application number
BRPI0613123A
Other languages
English (en)
Inventor
Kaps Christian
Tánczos Eszter
Sittinger Michael
Original Assignee
Biotissue Ag
Transtissue Tech Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotissue Ag, Transtissue Tech Gmbh filed Critical Biotissue Ag
Publication of BRPI0613123A2 publication Critical patent/BRPI0613123A2/pt
Publication of BRPI0613123B1 publication Critical patent/BRPI0613123B1/pt
Publication of BRPI0613123B8 publication Critical patent/BRPI0613123B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3616—Blood, e.g. platelet-rich plasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

enxerto sem células. a presente invenção refere-se a um enxerto sem células, que compreende (i) uma matriz coesiva, formadora de estruturas com porosidade aberta feita a partir de material biologicamente e farmaceuticamente aceitável e (ii) soro. em uma das modalidades particularmente preferidas, a matriz contém adicionalmente um gel. em virtude de um segundo aspecto, é proposto um método de produzir tal enxerto sem células, pelo que a matriz e o gel, se um é provido, são colocados em contato com o soro. o enxerto pode, opcionalmente, ser secado com o soro. alternativamente, a matriz e o gel, se um é provido, estão em estado seco antes de serem colocados em contato com o soro. em virtude de um terceiro aspecto, finalmente, a invenção propõe o uso do enxerto sem células para a regeneração de tecidos e em particular para a regeneração cartilagem e/ou osso.
BRPI0613123A 2005-06-30 2006-06-29 enxerto sem células BRPI0613123B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005030614.4 2005-06-30
DE102005030614.4A DE102005030614B4 (de) 2005-06-30 2005-06-30 Zellfreies Transplantat, dessen Verwendung, Verfahren zu dessen Herstellung, dabei hergestellte Matrix mit Gel und Verfahren zur Herstellung dieser Matrix mit Gel
PCT/EP2006/006281 WO2007003324A2 (de) 2005-06-30 2006-06-29 Zellfreies transplantat aus matrix und serum

Publications (3)

Publication Number Publication Date
BRPI0613123A2 BRPI0613123A2 (pt) 2010-12-21
BRPI0613123B1 BRPI0613123B1 (pt) 2018-10-30
BRPI0613123B8 true BRPI0613123B8 (pt) 2021-06-22

Family

ID=37562376

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0613123A BRPI0613123B8 (pt) 2005-06-30 2006-06-29 enxerto sem células

Country Status (12)

Country Link
US (1) US9125871B2 (pt)
EP (1) EP1933767B1 (pt)
JP (1) JP4871356B2 (pt)
CN (1) CN101184450B (pt)
AU (1) AU2006265361B2 (pt)
BR (1) BRPI0613123B8 (pt)
CA (1) CA2606622C (pt)
DE (1) DE102005030614B4 (pt)
ES (1) ES2419160T3 (pt)
IL (1) IL188305A (pt)
RU (1) RU2404820C2 (pt)
WO (1) WO2007003324A2 (pt)

Families Citing this family (13)

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DE102005030614B4 (de) 2005-06-30 2014-05-08 Biotissue Ag Zellfreies Transplantat, dessen Verwendung, Verfahren zu dessen Herstellung, dabei hergestellte Matrix mit Gel und Verfahren zur Herstellung dieser Matrix mit Gel
DK1948259T3 (en) * 2005-10-26 2017-04-10 Genesis Tech Ltd ACELLULAR BIOabsorbable Tissue Regeneration Matrices Produced by Incubation of ACELLULAR BLOOD PRODUCTS
DE102006047346A1 (de) 2006-10-06 2008-04-10 Transtissue Technologies Gmbh Matrix-Gel-Transplantat ohne Zellen
ITFI20080070A1 (it) 2008-04-04 2009-10-05 Azienda Ospedaliero Universitaria Careggi Matrice extracellulare comprendente fattori piastrinici.
EP2992856A1 (en) 2008-12-15 2016-03-09 Allergan, Inc. A prosthetic device and method of manufacturing the same
US9326840B2 (en) 2008-12-15 2016-05-03 Allergan, Inc. Prosthetic device and method of manufacturing the same
US9204954B2 (en) 2008-12-15 2015-12-08 Allergan, Inc. Knitted scaffold with diagonal yarn
US9204953B2 (en) 2008-12-15 2015-12-08 Allergan, Inc. Biocompatible surgical scaffold with varying stretch
US9308070B2 (en) * 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
EP2749299B1 (en) 2011-08-23 2018-04-25 Mochida Pharmaceutical Co., Ltd. Composition for regeneration of cartilage
RU2602775C2 (ru) * 2015-04-07 2016-11-20 Акционерное общество "Зеленоградский нанотехнологический центр" Биодеградируемый материал на основе молекул белков и волокон биополимеров для обеспечения ускоренного восстановления тканей и способ его получения
WO2025088167A1 (en) 2023-10-26 2025-05-01 Charité - Universitätsmedizin Berlin Implant comprising a plurality of channels

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Also Published As

Publication number Publication date
US20080206302A1 (en) 2008-08-28
US9125871B2 (en) 2015-09-08
WO2007003324A2 (de) 2007-01-11
HK1117028A1 (en) 2009-01-09
WO2007003324A3 (de) 2007-08-16
RU2404820C2 (ru) 2010-11-27
ES2419160T3 (es) 2013-08-19
IL188305A0 (en) 2008-04-13
JP4871356B2 (ja) 2012-02-08
BRPI0613123A2 (pt) 2010-12-21
CA2606622C (en) 2011-05-17
JP2008541905A (ja) 2008-11-27
IL188305A (en) 2012-01-31
CA2606622A1 (en) 2007-01-11
CN101184450A (zh) 2008-05-21
CN101184450B (zh) 2013-03-13
BRPI0613123B1 (pt) 2018-10-30
DE102005030614B4 (de) 2014-05-08
AU2006265361A1 (en) 2007-01-11
RU2008103337A (ru) 2009-08-10
DE102005030614A1 (de) 2007-01-11
AU2006265361B2 (en) 2009-10-22
EP1933767B1 (de) 2013-04-03
EP1933767A2 (de) 2008-06-25

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