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CA2283648A1 - Excipient polymere - Google Patents

Excipient polymere Download PDF

Info

Publication number
CA2283648A1
CA2283648A1 CA002283648A CA2283648A CA2283648A1 CA 2283648 A1 CA2283648 A1 CA 2283648A1 CA 002283648 A CA002283648 A CA 002283648A CA 2283648 A CA2283648 A CA 2283648A CA 2283648 A1 CA2283648 A1 CA 2283648A1
Authority
CA
Canada
Prior art keywords
stereoselective
bioactive molecule
biocompatible
polymeric carrier
complementary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002283648A
Other languages
English (en)
Other versions
CA2283648C (fr
Inventor
Avraham J. Domb
Zeev Zehavi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Efrat Biopolymers Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2283648A1 publication Critical patent/CA2283648A1/fr
Application granted granted Critical
Publication of CA2283648C publication Critical patent/CA2283648C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002283648A 1998-01-14 1999-01-14 Excipient polymere Expired - Fee Related CA2283648C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL12293398A IL122933A (en) 1998-01-14 1998-01-14 Polymeric carrier for delivery of a bioactive molecule
IL122933 1998-01-14
PCT/IL1999/000023 WO1999036100A2 (fr) 1998-01-14 1999-01-14 Excipient polymere

Publications (2)

Publication Number Publication Date
CA2283648A1 true CA2283648A1 (fr) 1999-07-22
CA2283648C CA2283648C (fr) 2007-04-17

Family

ID=11071088

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002283648A Expired - Fee Related CA2283648C (fr) 1998-01-14 1999-01-14 Excipient polymere

Country Status (6)

Country Link
EP (1) EP0967998A2 (fr)
JP (1) JP2001515522A (fr)
AU (1) AU1888999A (fr)
CA (1) CA2283648C (fr)
IL (1) IL122933A (fr)
WO (1) WO1999036100A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1183016B1 (fr) * 1999-02-19 2004-04-21 Universiteit Utrecht Hydrogels stereocomplexes
WO2000050050A1 (fr) * 1999-02-23 2000-08-31 Isis Pharmaceuticals, Inc. Formulation multiparticulaire
WO2002083166A1 (fr) * 2001-04-10 2002-10-24 Santen Pharmaceutical Co., Ltd. Complexes de polymeres d'interferons et leur utilisation medicinale
DE10154924A1 (de) * 2001-11-08 2003-05-28 Medinnova Ges Med Innovationen Bioabbaubare Kopolymere
CN1290893C (zh) * 2002-05-03 2006-12-20 詹森药业有限公司 聚合物微乳状液
US8012488B2 (en) 2005-02-18 2011-09-06 Nof Corporation Polyoxyalkylene derivative
US8067398B2 (en) 2005-06-01 2011-11-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Biodegradable polymers having a pre-determined chirality
WO2007088957A1 (fr) * 2006-02-03 2007-08-09 National University Corporation Hokkaido University Nanodisque comprenant un copolymere sequence
EP2135887B1 (fr) 2008-06-18 2010-12-22 Instytut Biopolimeròw I Wlókien Chemicznych Procédé de production de poudre stéréocomplexe d'acide polylactique
CA2804815C (fr) * 2010-07-09 2016-06-07 The University Of Tokyo Composition d'administration d'acides nucleiques, composition d'excipient, composition pharmaceutique contenant la composition d'administration d'acides nucleiques ou la composition d'excipient et methode d'administration d'acides nucleiques
CN108559084B (zh) * 2018-04-13 2020-12-04 华东理工大学 一种聚乳酸基疏水薄膜的制备方法
CN109908106A (zh) * 2019-03-04 2019-06-21 北京化工大学 一种可供静脉注射的甲氨蝶呤纳米胶囊及其制备方法
JP7050734B2 (ja) * 2019-09-30 2022-04-08 鳥居薬品株式会社 舌下アレルゲン免疫療法におけるフィルム製剤
CN115785471B (zh) * 2022-12-16 2023-08-08 华中科技大学 一种二氧化碳基超分子聚合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6136321A (ja) * 1984-07-27 1986-02-21 Daicel Chem Ind Ltd 新規なポリマ−およびその樹脂組成物
US4902515A (en) * 1988-04-28 1990-02-20 E. I. Dupont De Nemours And Company Polylactide compositions
CA2046830C (fr) * 1990-07-19 1999-12-14 Patrick P. Deluca Systeme d'administration des medicaments comprenant une interaction entre une proteine ou une polypeptide et un polymere hydrophobe biodegradable

Also Published As

Publication number Publication date
EP0967998A2 (fr) 2000-01-05
JP2001515522A (ja) 2001-09-18
IL122933A (en) 2005-03-20
WO1999036100A3 (fr) 1999-09-23
AU1888999A (en) 1999-08-02
IL122933A0 (en) 1998-08-16
CA2283648C (fr) 2007-04-17
WO1999036100A2 (fr) 1999-07-22

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