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CN1080930A - 组胺衍生物及其用作免疫调节剂的方法 - Google Patents

组胺衍生物及其用作免疫调节剂的方法 Download PDF

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Publication number
CN1080930A
CN1080930A CN93102514A CN93102514A CN1080930A CN 1080930 A CN1080930 A CN 1080930A CN 93102514 A CN93102514 A CN 93102514A CN 93102514 A CN93102514 A CN 93102514A CN 1080930 A CN1080930 A CN 1080930A
Authority
CN
China
Prior art keywords
compound
histamine
derivatives
mouse
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN93102514A
Other languages
English (en)
Chinese (zh)
Inventor
K·L·梅尔蒙
M·古德曼
P·卡斯罗波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immulogic Pharmaceutical Corp
Original Assignee
Immulogic Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immulogic Pharmaceutical Corp filed Critical Immulogic Pharmaceutical Corp
Publication of CN1080930A publication Critical patent/CN1080930A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN93102514A 1992-01-26 1993-01-22 组胺衍生物及其用作免疫调节剂的方法 Pending CN1080930A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US826,528 1992-01-26
US82618092A 1992-01-27 1992-01-27

Publications (1)

Publication Number Publication Date
CN1080930A true CN1080930A (zh) 1994-01-19

Family

ID=25245912

Family Applications (2)

Application Number Title Priority Date Filing Date
CN93102514A Pending CN1080930A (zh) 1992-01-26 1993-01-22 组胺衍生物及其用作免疫调节剂的方法
CN93102513A Pending CN1079908A (zh) 1992-01-26 1993-01-22 组胺衍生物及其用作免疫调节剂的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN93102513A Pending CN1079908A (zh) 1992-01-26 1993-01-22 组胺衍生物及其用作免疫调节剂的方法

Country Status (7)

Country Link
EP (1) EP0626847A1 (fr)
JP (1) JPH07503470A (fr)
CN (2) CN1080930A (fr)
AU (1) AU3591593A (fr)
CA (1) CA2128516A1 (fr)
MX (1) MX9300393A (fr)
WO (1) WO1993014754A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6498181B1 (en) 1999-01-06 2002-12-24 Maxim Pharmaceuticals Synergistic tumorcidal response induced by histamine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521405A (en) * 1982-05-17 1985-06-04 John McMichael Methods and materials for treatment of disease states involving immunological factors
US4996221A (en) * 1987-01-13 1991-02-26 The Board Of Trustees Of The Leland Stanford Junior University Histamine derivatives as immune modulators

Also Published As

Publication number Publication date
AU3591593A (en) 1993-09-01
MX9300393A (es) 1994-07-29
EP0626847A1 (fr) 1994-12-07
JPH07503470A (ja) 1995-04-13
CA2128516A1 (fr) 1993-08-05
WO1993014754A1 (fr) 1993-08-05
CN1079908A (zh) 1993-12-29

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication