CN102228725A - Dry powder administration device - Google Patents
Dry powder administration device Download PDFInfo
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- CN102228725A CN102228725A CN2011101567684A CN201110156768A CN102228725A CN 102228725 A CN102228725 A CN 102228725A CN 2011101567684 A CN2011101567684 A CN 2011101567684A CN 201110156768 A CN201110156768 A CN 201110156768A CN 102228725 A CN102228725 A CN 102228725A
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- 238000003860 storage Methods 0.000 claims abstract description 35
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention discloses a dry powder administration device, and belongs to the field of administration sets. The dry powder administration device comprises a flow channel component, a medical powder storage container and an administration metering component, and is characterized in that: a shell is arranged; the upper part of the shell is provided with the inverted-cone-shaped medical powder storage container; a ring-shaped manual rotary part is arranged at the periphery of the upper part of the shell; a rotary slipway is arranged on the outer surface of the upper part of the shell, and a slide block is arranged corresponding to the inner side face of the ring-shaped manual rotary part; a first elastic part is arranged between the ring-shaped manual rotary part and the upper part of the shell; an air inlet is formed at one end of the rotary slipway; the flow channel component is arranged in the shell; a suction nozzle is arranged on the outer side of the shell and a suction nozzle sleeve is arranged outside the suction nozzle; a medicine inlet is arranged on the horizontal part of the flow channel component; the administration metering component is arranged below the inverted-cone-shaped medical powder storage container; and the flow channel component is connected with the air inlet, the administration metering component and the suction nozzle through air channels in turn. By adopting an air inlet omniseal structure, before medical powder is added, the medical powder metering component is dried and can accurately meter the dosage of the medical powder and avoid 'excessive dosage' administration.
Description
Technical field
The invention belongs to medium is imported the intravital instrument field of people, relate in particular to a kind of inhalation-type drug administration apparatus that is used for the powdered medicine of prescribed dose is sent into the patient oral cavity.
Background technology
In the modern medical service technology, patient's route of administration is generally included oral, suck sublingual administration, external application, rectally, several administering modes such as injection.
Since through the oral cavity or snuffing go into to make medicine directly to go into blood by the mucosa absorption of oral cavity or nose, can walk around " the first mistake " effect of liver, so for the treatment/administration of numerous disease (modal is exactly asthma), the first-elected administering mode that (or nose) sucks through the oral cavity of the administering mode that takes effect fast.
Existing be used for the treatment of respiratory tract disease such as asthma, through the device of inhalation mode, mainly contain aerosol drug delivery device and dry powder inhalation device two big classes.
For the aerosol drug delivery device, raising along with the home and abroad environmental consciousness, fluoric ether (CFC, chlorofluorocarbon) the class aerosol is eliminated gradually, and (Chlorofluorocarbons (CFCs) is one group of alkyl halide of being made up of chlorine, fluorine and carbon, is being used for doing refrigerator refrigerant by people at first, but because it can play decomposition to ozone layer, from on January 1st, 1996, the Chlorofluorocarbons (CFCs) production that formally is under an embargo), new comparatively ideal aerosol is further in the research.
On the other hand, if use the aerosol type doser, the patient must be able to coordinate the rhythm of " spraying " and " suction " two actions preferably, just can reach comparatively ideal medicine and suck effect.
And the operation of dry powder suction type medicator, then fully by patient's active consciousness decision, the problem that does not have " injection " and " suction " to coordinate.
For the dry powder suction type medicator, divide from the angle that medicine stores, mainly be divided into two big classes at present: barrier packaging formula and reservoir type.
1) barrier packaging formula dry powder suction type medicator:
Receiving the device product with commercially available " Shu Li repeatedly " standard is example, its concrete structure is on May 2nd, 2007 in the day for announcing, Granted publication number is existing description the in the Chinese invention patent of CN 1313171C, this patent documentation discloses a kind of " inhaler ", this inhaler has a plurality of chambers that separate into array, and each chamber comprises the medicine of dosing; And mobile one by one chamber with the aligned lever of inlet hole that constitutes the mouth of pipe, each chamber comprises inward flange and outward flange, a plurality of chambers are closed by sealant.This inhaler also has sealant is lifted away from the inward flange of chamber and outward flange to open the mechanism of the air duct that is made of this chamber and sealant.Therefore, in use, when by this mouth of pipe when air-breathing, the air-flow in the air flow passage is being carried the medicated powder in the chamber secretly, is evacuated to the inhaler outside by air by this mouth of pipe.
Find that in actual use the volume of this type of dry powder suction type medicator is bigger usually, the manufacturing/acquisition cost of whole suction apparatus is also higher relatively.
2) reservoir type dry powder suction type medicator:
Such doser is representative with commercially available all guarantors (Turbuhaler) product.
Granted publication day is on July 12nd, 2000, Granted publication number is in the Chinese invention patent of CN 1054304C, a kind of " medicament dispensing device " disclosed, this device has can pack into a kind of dust container of efflorescence medicament, certain volumetrical air, a measuring room that is communicated with dust container, and this measuring room graded is told the efflorescence medicament quantitatively from container.
Granted publication day is on March 29th, 2006, Granted publication number is in the Chinese invention patent of CN 1247275C, a kind of " inhalation apparatus " disclosed, it comprises: a flow channel, formed by a plurality of surfaces, user passes through this passage by the air-breathing air draught that carries described dosage of powder that makes; A metering units is used for the powder of doses is provided to described flow channel, so that take powder by air draught.
As seen, this type of reservoir type dry powder suction type medicator all is provided with a dust container and corresponding metering element usually, tells the efflorescence medicament quantitatively by metering element gradation from dust container.
Do/bigger problem of micropowder administration is that powdery granule has bigger surface energy, forms " reunion " state easily, thereby has caused bigger difficulty for the metering of each dosage of depot medicine.
And, have now in the disclosed product structure of technical scheme of commercially available reservoir type dry powder doser product and Chinese patent ZL 98805080.3, because its dry powder metering device is a through hole, is prone to Lou powder phenomenon, and can't guarantees to avoid the problem of " overdose " administration.
In addition; the commercially available prod of existing reservoir type dry powder doser; air inlet/hole that it communicates with runner; normally open on housing; after the protectiveness outer housing/shell of dry powder doser is removed; air inlet just is exposed in the air; the gas circuit path (air inlet/hole-runner-dust container-suction nozzle) that has caused communicating with dust container in the dry powder doser is in " the often opening " state that always communicates with the external world; contained moisture is easy to enter in the dust container in the outside air; cause medicament dry powder easy " making moist " caking in the dust container, influence the accuracy and the result of use of administration metering.
Summary of the invention
Technical problem to be solved by this invention provides a kind of dry powder doser, it adopts the all-sealed structure of suction nozzle and air inlet, by the rational structure setting, before adding medicated powder at every turn, can carry out drying to medicated powder measurement structure/assembly, avoided making moist and luming of medicament dry powder in the dust container, realized more accurately measuring the function of medicated powder dosage, and avoided the danger of " overdose " administration.
Technical scheme of the present invention is: a kind of dry powder doser is provided, at least comprise flow channel component, medicated powder storage capsule and administration gauge assembly, described flow channel component comprises suction nozzle and runner parts, it is characterized in that: a housing that is constituted by last main component and following main component is set; On the top of housing, inverted cone shape medicated powder storage capsule is set; In the upper periphery of housing, the manual rotating part of a ring-type is set; Outer surface on housing top is provided with rotating slideway, and at the medial surface of the manual rotating part of ring-type, correspondence is provided with slide block; Between manual rotating part of ring-type and housing top, first elastomeric element is set; End in described rotating slideway is provided with air inlet; In the inside of housing, the runner parts are set; The outside at housing is provided with suction nozzle, in the outside of suction nozzle, the suction nozzle cover is set; The head end of described runner parts is connected with the air inlet gas circuit, and the end of runner parts is connected with the suction nozzle gas circuit, and the horizontal position at the runner parts is provided with feeding opening; Below inverted cone shape medicated powder storage capsule, the administration gauge assembly is set; Described runner parts gas circuit successively connect air inlet, administration gauge assembly and suction nozzle.
Concrete, described rotating slideway comprises upper and lower rotating slideway arranged side by side and first, second hoistway that is connected upper and lower rotating slideway head, end; The manual rotating part of described ring-type can be done the rotation in the predetermined angle and the lifting/lowering of assigned address on last main component under the guiding/restriction/effect of last/following rotating slideway, the first/the second hoistway, slide block and first elastomeric element.
Described predetermined angle is 120 degree.
Described assigned address is head, the terminal position of upper and lower rotating slideway.
At the described end of horizontal slideway down, air inlet is set.
Its described administration gauge assembly comprises the dosed administration dish that has central shaft, at the spring cup below the dosed administration dish, at second elastomeric element between main component and the spring cup down.
The head end of described central shaft, the top of running through main component is provided with, and the axle head end on main component top is provided with triangular key on central shaft passes; In the centre of the manual rotating part of described ring-type, correspondence is provided with the triangle slotted eye.
Described center the tip of the axis is connected with following main component rotationally.
In the one side of described dosed administration dish towards inverted cone shape medicated powder storage capsule, three administration grooves are set, described administration groove is uniformly distributed along the circumference on the dosed administration dish.
The feeding opening position of described runner parts is with the corresponding setting of distribution circumference at three administration groove places.
In the upper end of described central shaft, engagement type clutch component is set.
Further, uniform on the circumference of described dosed administration dish three elastic positioning cards are set, the inboard of infra main component, correspondence is provided with three detents, described elastic positioning card and detent are complementary, in dosed administration dish rotating process, guarantee that the angle that each dosed administration dish rotates is 1/3rd of a circumference, give simultaneously one of user clear and definite be rotated in place signal.
Its described engagement type clutch component comprises engaging tooth spare and following engaging tooth spare, and described upper and lower engaging tooth spare is sleeved on the central shaft.
Described first elastomeric element or second elastomeric element are spring.
Further, the top at described housing is provided with dry component, described dry component comprise with the outlet of inverted cone shape medicated powder storage capsule in the same way opening tubular shell and be arranged in the graininess hygroscopic agent of housing.
Described dry component becomes 120 degree angle settings with longitudinal center's axis of the relative housing of inverted cone shape medicated powder storage capsule.
The outlet of described dry component or inverted cone shape medicated powder storage capsule is with the corresponding setting of distribution circumference at three administration groove places.
On described suction nozzle cover and the manual rotating part of ring-type, correspondence is provided with positioning convex and locating piece groove respectively, when the suction nozzle cover is in " covering " state, described positioning convex and locating piece groove cooperatively interact, stop between manual rotating part of ring-type and the last main component to rotate, constitute anti-misoperation frame for movement.
The application also provides the inhalation step of above-mentioned dry powder doser, it is characterized in that described dry powder doser finishes whole inhalation process according to following step:
A, remove the suction nozzle cover downwards;
B, manually be rotated counterclockwise the manual rotating part of ring-type, to 120 degree extreme positions;
C, the manual rotating part of ring-type are upwards upspring automatically;
D, the manual manual rotating part of reverse rotation ring-type are to inverse limit 120 degree positions;
E, patient suck medicated powder through suction nozzle;
F, manually press the manual rotating part of ring-type;
G, cover the suction nozzle cover.
In above-mentioned whole inhalation process, above-mentioned dry powder doser is finished whole " drying-confession medicine-administration " process according to following order:
A1, remove the suction nozzle cover downwards, remove anti-error rotary machine restriction the manual rotating part of ring-type;
B1, manually be rotated counterclockwise the manual rotating part of ring-type, to 120 degree extreme positions, in the described administration gauge assembly the first administration groove of dosed administration dish accept inverted cone shape medicated powder storage capsule for medicine, realize quantitatively for medicine;
C1, the manual rotating part of ring-type are upwards upspring automatically, and air inlet open possesses the inhalation condition; Simultaneously, the triangular key of axle head end enters the triangle slotted eye at the manual rotating part of ring-type middle part among the described administration gauge assembly, for the rotation next time of dosed administration dish provides prerequisite;
D1, the manual manual rotating part of reverse rotation ring-type to inverse limit 120 degree positions, contain the feeding opening of the first administration groove alignment runner parts of medicated powder, finish for the medicine process, make the patient suck medicated powder and possess prerequisite;
E1, patient suck medicated powder through suction nozzle, and the gas that is used to deliver medicated powder enters the dry powder doser from air inlet, and longshore current road parts are sent into patient oral cavity with the medicated powder in the dosed administration dish first administration groove through suction nozzle to feeding opening, finish the administration process;
F1, manually press the manual rotating part of ring-type, the second administration groove and the dry component position alignment of dosed administration dish in the described administration gauge assembly are accepted dryly, carry out the preparation in advance that next time supplies medicine;
G1, cover the suction nozzle cover, recover anti-error rotary machine restriction the manual rotating part of ring-type.
Compared with the prior art, advantage of the present invention is:
1. adopt the dual all-sealed structure of suction nozzle and air inlet, have only in the suction nozzle cover is in the of short duration time range of this section that the manual rotating part of " removing " state and ring-type upsprings after through rotation for the first time, the carrier gas path of this dry powder doser just communicates with outside air, suck medicated powder the patient, after manually pressing the manual rotating part of ring-type, the carrier gas path is cut off again with " communicating " state of outside air, avoided during protectiveness outer housing/shell is opened, the carrier gas path is in the problem of " the often opening " state that always communicates with the external world, has reduced the chance of making moist and luming and the possibility of medicament dry powder in the dust container;
2. three administration groove structures are set,, can avoid taking place the problem of " overdose " administration because it is groove rather than through hole;
3. by dry component is set, before adding medicated powder at every turn, medicated powder gauge assembly/structure (specifically being each administration groove of dosed administration dish) is carried out drying, continuous rotation along with the dosed administration dish, move on to certain administration groove of the outlet below of inverted cone shape medicated powder storage capsule at every turn, always cross through super-dry; By each administration groove being taked the operational mode of " dry earlier, powder charge again ", further guaranteed the accurate of dosage.
Description of drawings
Fig. 1 is the cross-sectional view of dry powder doser of the present invention;
Fig. 2 is the three-dimensional decomposition texture sketch map of dry powder doser of the present invention;
Fig. 3 is dry component and inverted cone shape medicated powder storage capsule structural representation;
Fig. 4 is the structural representation that the runner parts get;
Fig. 5 is the structural representation of rotating-/ lifting slideway;
Fig. 6 is the engagement type clutch component structural representation of central shaft;
Fig. 7 is the drive mechanism sketch map;
Fig. 8 is rotated counterclockwise operation chart;
Fig. 9 is clockwise operation chart;
Figure 10 depresses the manual rotating part of ring-type, finishes the administration operation chart.
1 is central shaft among the figure, and 1-1 is a central shaft hole, and 2 is the locating piece groove, 3 is the manual rotating part of ring-type, and 8 is last main component, and 10 is the runner parts, 10-1 is the head end of runner, and 10-2 is the end of runner, and 10-3 is the feeding opening of runner, 11 is suction nozzle, and 11-1 is the suction nozzle cover, and 13 is the dosed administration dish, 14 are the administration groove, and 15 is spring cup, and 16 are following main component, 17 is drying tube, and 19 is inverted cone shape medicated powder storage capsule, and 20 is second spring, 23 is rotating slideway, and 23-1 is last rotating slideway, and 23-2 is following rotating slideway, 23-3 is first hoistway, 23-4 is second hoistway, and 24 is elastic positioning card, and 25 is first spring, 26 is slide block, 27 is last engaging tooth spare, and 28 are following engaging tooth spare, and 29 is detent, 31 is triangular key, and 32 is the triangle slotted eye.
The specific embodiment
The present invention will be further described below in conjunction with accompanying drawing.
Among Fig. 1 and Fig. 2, this dry powder doser is provided with a housing that is constituted by last main component 8 and following main component 16; In the upper periphery of housing, the manual rotating part 3 of a ring-type is set; Outer surface on housing top is provided with rotating slideway 23, and at the medial surface of the manual rotating part of ring-type, correspondence is provided with slide block 26; Between manual rotating part of ring-type and housing top, first elastomeric element 25 is set; End in described rotating slideway is provided with air inlet; In the inside of housing, runner parts 10 are set; In the outside of housing, suction nozzle 11 is set, the head end of described runner parts is connected with the air inlet gas circuit, and the end of runner parts is connected with the suction nozzle gas circuit, and the horizontal position at the runner parts is provided with feeding opening; Below inverted cone shape medicated powder storage capsule, the administration gauge assembly is set; Described runner parts gas circuit successively connect air inlet, administration gauge assembly and suction nozzle.
The administration gauge assembly comprises the dosed administration dish 13 that has central shaft 1, the spring cup 15 that is positioned at dosed administration dish below, and second elastomeric element 20 between following main component and spring cup.
As seen from the figure, described center the tip of the axis is connected with following main component rotationally.By the spring cup of dosed administration dish below, in the effect of second elastomeric element between main component and the spring cup down, specified rate provides one to make progress to batch pan, is adjacent to the active force of runner parts horizontal position feeding opening.
In the one side (in Fig. 2 be upwards one side) of dosed administration dish towards inverted cone shape medicated powder storage capsule, three administration grooves 14 are set, described administration groove is uniformly distributed along the circumference on the dosed administration dish.
The outlet bottom surface of administration groove and inverted cone shape medicated powder storage capsule is close to; Medicated powder flows into the administration groove of dosed administration dish from inverted cone shape medicated powder storage capsule, fill to be the patient and once to suck the required dosage of medicament (abbreviating " dosage " in the industry as).
Because the administration groove is not a through hole,, reached the purpose of accurate metering so, implement just to have avoided the problem of " overdose " administration in the process of administration when the moving dosed administration dish rotation of central shaft rotating band.
Uniform on the circumference of dosed administration dish three elastic positioning cards 24 are set, the inboard of infra main component, correspondence is provided with three detents 29, elastic positioning card and detent match, in dosed administration dish rotating process, give one of user clear and definite be rotated in place signal, simultaneously, guarantee that the angle that each dosed administration dish rotates is 1/3rd of a circumference.
Aforesaid first elastomeric element or second elastomeric element are spring.
Among Fig. 3, on the top of housing (being last main component 8 among the figure), outlet down is provided with an inverted cone shape medicated powder storage capsule 19.
Simultaneously, on the top of housing, also be provided with dry component 17, dry component comprises with the tubular shell of the equidirectional opening of outlet of inverted cone shape medicated powder storage capsule and is arranged in the graininess hygroscopic agent of housing.
Dry component and inverted cone shape medicated powder storage capsule become 120 degree angle settings with respect to longitudinal center's axis of housing (centrage with the axis hole 1-1 of central shaft among the figure is represented longitudinal center's axis).
The outlet of dry component and/or inverted cone shape medicated powder storage capsule is with the corresponding setting of distribution circumference at three administration groove places.
When of the rotation of certain administration groove along with the dosed administration dish, when arriving the outlet below of inverted cone shape medicated powder storage capsule, dry powder pharmaceutical in the inverted cone shape medicated powder storage capsule is poured into this administration groove, because the outlet bottom surface of administration groove and inverted cone shape medicated powder storage capsule is close to, and the administration groove is not a through hole, so when the moving dosed administration dish rotation of central shaft rotating band, implement in the process of administration, just avoid the problem of " overdose " administration, reached the purpose of accurate administration.
Equally, when of the rotation of certain administration groove along with the dosed administration dish, when arriving dry component tubular shell opening below, owing in the tubular shell desiccant is housed, so this administration groove will obtain drying.
Rotation direction according to the dosed administration dish, determined that any one administration groove will be at first through dry component tubular shell opening below (drying), pass through the outlet below (powder charge) of inverted cone shape medicated powder storage capsule again, pass through the feeding opening (suction medicine) of runner parts below at last; So, inhale in the complete procedure of medicated powder a patient, three administration grooves are being always cycle rotation (the dosed administration dish that is actually administration groove place is being made directed cycle rotation), and then can realize the whole course of action of " drying, powder charge powder, inhale medicated powder ".
Among Fig. 4, the runner parts are a head, end openings, and also have feeding opening below the by-level section, and the air flue member of forcing the flow direction/runner is provided for medicine carrying gas; Wherein, the air inlet (not shown) gas circuit that is positioned on the upper shell among the head end 10-1 of runner parts and Fig. 2 is connected, the terminal 10-2 of described runner parts is connected with suction nozzle 11 gas circuits among Fig. 2, below runner parts interlude/horizontal position, be provided with downward opening feeding opening 10-3 (dotting among the figure).
The feeding opening position of runner parts with the corresponding setting of distribution circumference at three administration groove places of dosed administration rotating disk, is close to the administration groove of dosed administration rotating disk and is aimed at.
By as can be known shown in Figure 2, runner parts gas circuit successively connect air inlet, administration gauge assembly (actual is the administration groove of dosed administration dish) and suction nozzle.
Because the whole employing camber line design of runner so there is not any dead angle, does not have residual medicated powder, thereby has guaranteed the accurate of dosage.
Among Fig. 5, be arranged at the rotating slideway of the outer surface (reality is the outer surface of last main body) on housing top, comprise the first hoistway 23-3 and the second hoistway 23-4 of last rotating slideway 23-1 arranged side by side, following rotating slideway 23-2, the upper and lower rotating slideway head of connection, end.
By as can be known shown in Figure 1, at the medial surface of the manual rotating part of ring-type, correspondence is provided with slide block 26.
The manual rotating part 3 of ring-type shown in Fig. 1 under the guiding/restriction/effect of last/following rotating slideway, the first/the second hoistway, slide block and first elastomeric element, can be done the rotation in the predetermined angle and the lifting/lowering of assigned address on last main component.
Above-mentioned predetermined angle is 120 degree.
Above-mentioned assigned address is head, the terminal position of upper and lower rotating slideway.
Further, the end of the horizontal slideway of infra is provided with air inlet.
After adopting said structure, have only in the suction nozzle shown in Fig. 8 cover 11-1 is in the of short duration time range of this section that " removing " state that is rotated down and the manual rotating part of ring-type pop up after through rotation for the first time, the carrier gas path of this dry powder doser (air inlet-runner-suction nozzle) just communicates with outside air.
The patient suck medicated powder, manually press the manual rotating part of ring-type after; described carrier gas path is cut off again with " communicating " state of outside air; thereby solved existing dry powder doser during protectiveness outer housing/shell is opened; the carrier gas path is in the problem of " the often opening " state that always communicates with the external world, has reduced the chance of making moist and luming and the possibility of medicament dry powder in the dust container.
Among Fig. 6,, engagement type clutch component is set in the upper end of central shaft 1.
Described engagement type clutch component comprises engaging tooth spare 27 and following engaging tooth spare 28, and described upper and lower engaging tooth spare is sleeved on the central shaft.
As shown in Figure 1, last engaging tooth spare and the manual rotating part one of ring-type, and the manual rotating part of ring-type is after rotation/rising under the guiding of the rotating slideway and first spring and the effect, described upper and lower engaging tooth spare is in released state, the rotation of the manual rotating part of ring-type can not exert an influence to following engaging tooth spare.
Have only when the manual rotating part of ring-type is in down position, upper and lower engaging tooth spare just is in bonding state, and then the rotation of the manual rotating part of ring-type this moment is transmitted to down engaging tooth spare by last engaging tooth spare, drives it and together rotates.
Among Fig. 7, the head end of described central shaft, the top of running through main component and the manual rotating part of ring-type is provided with, and the axle head end on main component top is provided with triangular key 31 on central shaft passes.
In the centre of the manual rotating part of described ring-type, correspondence is provided with triangle slotted eye 32.
Under of the guiding and effect of the manual rotating part 3 of ring-type at the rotating slideway and first spring, after the rotation/rising, the triangular key that is arranged on the central shaft head end just in time embeds in the triangle slotted eye, the then rotation of the manual rotating part of ring-type this moment, drive mechanism by triangle slotted eye-triangular key, the drive central shaft rotates, and then drives the rotation of dosed administration dish.
When the manual rotating part of ring-type descends under the downward effect of external force, triangular key is deviate from from the triangle slotted eye, then the rotation of the manual rotating part of ring-type this moment can not be transmitted to the dosed administration dish, thereby the orientation that has realized administration gauge assembly (central shaft---dosed administration dish) is rotated, and has created prerequisite for realizing " drying-confession medicine-administration " process.
In addition, the technical program is on suction nozzle cover (this is not shown) and the manual rotating part of ring-type, and correspondence is provided with positioning convex and locating piece groove 2 respectively; By Ben Tu and Fig. 8 as can be known, when the suction nozzle cover rotates up, when the suction nozzle cover was in " covering " state, described positioning convex and locating piece groove cooperatively interacted, and can stop between manual rotating part of ring-type and the last main component to rotate.When the suction nozzle cover is rotated down, when being in " removing " state, positioning convex and locating piece groove disengage, then allow to rotate between manual rotating part of ring-type and the last main component, thereby constituted one group simple for structure, reliable in action, the anti-misoperation frame for movement of being convenient to operate.
This dry powder doser is finished whole inhalation process according to following steps:
The first step as shown in Figure 8, is removed suction nozzle cover 11-1 downwards.
User is as long as slightly firmly move to backspin, the suction nozzle cover can be removed, the rectangle projection (being aforesaid positioning convex) that a projection is arranged in the suction nozzle cover, this projection is inserted when the suction nozzle cover entangles in the rectangular slot on the opposite position on the manual rotating part of ring-type (aforesaid locating piece groove 2), and this is in order to prevent that the patient from just rotating the such maloperation of the manual rotating part of ring-type and occurring before not taking off the suction nozzle cover.
In second step, user is rotated counterclockwise the manual rotating part of ring-type to 120 degree extreme positions.
The first administration groove of dosed administration dish is accepted the medicine that supplies of inverted cone shape medicated powder storage capsule in the administration this moment gauge assembly, realizes quantitatively for medicine.
In rotation 120 degree, an outstanding slide block (being aforesaid slide block) is arranged on the inwall of the manual rotating part of ring-type, it can be drawn to the lower right corner from the lower left corner counterclockwise along the following rotating slideway in the slideway in the last main component, whole process 120 degree.
In the 3rd step, as shown in Figure 9, the manual rotating part of ring-type is upwards upspring automatically, and air inlet open possesses the inhalation condition.
When slide block arrives the position in the following rotating slideway lower right corner, because the effect of first spring is arranged, so the manual rotating part of whole ring-type will be upspring, Ka Huakuaikou is a hollow out below the following rotating slideway, constitute air inlet, this moment, the air inlet of this hollow out was exposed under the air, so air inlet inserts atmosphere thus, reached the effect that can suck medicated powder.
When the manual rotating part of ring-type is upspring, the triangle slotted eye of the manual rotating part of ring-type (seeing the parts of the label 32 among Fig. 7) rises, just in time mesh with triangular key (seeing the parts of the label 31 among Fig. 7), the last engaging tooth spare 27 of one and being sleeved between the following engaging tooth spare 28 on the central shaft with it on this moment ring-type manual rotating part, owing to the rising of last engaging tooth spare disengages/engagement, for the rotation next time of dosed administration dish provides prerequisite.
In the 4th step, once more the manual rotating part of ring-type is rotated in a clockwise direction to 120 degree extreme positions.
As shown in Figure 9, this moment user the more manual rotating part 3 of ring-type is turned clockwise 120 the degree, the slide block of the manual rotating part of ring-type inboard will slide into the upper left corner on last rotating slideway, and because the engagement of triangular key and triangle slotted eye, 120 degree that rotate drive quantitative disk and rotate corresponding 120 degree, make the administration groove of filling medicated powder just in time move into feeding opening below the runner, finish, make the patient suck medicated powder and possess prerequisite for the medicine process.
The 5th step sucked medicated powder, finished the administration process.
The patient sucks medicated powder through suction nozzle, and the gas that is used to deliver medicated powder enters the dry powder doser from air inlet, and longshore current road parts are sent into patient oral cavity with the medicated powder in the dosed administration dish first administration groove through suction nozzle to feeding opening, finish the administration process.
In the 6th step, the administration groove is accepted dry, carries out the preparation in advance that next time supplies medicine.
As shown in Figure 10, the patient only need depress the manual rotating part 3 of ring-type, aforesaid corner block and triangular groove are broken away from, then upper and lower engaging tooth spare contacts once again/meshes, and the manual rotating part of ring-type when depressing slide block be stuck in the following bayonet socket place (as shown in Figure 5) of time rotating slideway, can not upspring, slide block also has been in initial position so again, uses next time for the patient.
At last, rotate up and put the suction nozzle cover, realize sealing fully, whole medication process just is through with.
Circulation so successively, in constantly using afterwards, three little grooves of quantitative disk turn clockwise always, and that does not stop is in " powder charge → treat suction → drying " such process.
The technical program adopts the dual all-sealed structure to suction nozzle and air inlet, and each administration groove is taked the operational mode of " dry earlier, powder charge again ", avoided making moist and luming of medicament dry powder in the dust container, realized more accurately measuring the function of medicated powder dosage, and avoided the danger of " overdose " administration.
Simultaneously, the technical program drives the dosed administration dish and rotates in proper order by the rotation/lifting of the manual rotating part of ring-type, for " dry earlier, the powder charge again " of each administration groove created prerequisite.
In addition, in the technical program by between dosed administration dish and following main component, elastic positioning card and detent being set, both guaranteed the each angle of rotating of dosed administration dish, can give clear and definite " being rotated in place " signal of user again, and made things convenient for and used and operate.
At last, in the technical program between suction nozzle cover and the following main component employing pivot pin be connected, both made things convenient for use, can avoid loss again, help to guarantee whole result of use, to the drying effect of administration groove and the degree of accuracy of administration metering, also can prolong the service life of whole device.
The technical program is applicable to design, the manufacturing field of the dry powder suction type medicator of all size.
Claims (14)
1. a dry powder doser comprises flow channel component, medicated powder storage capsule and administration gauge assembly at least, and described flow channel component comprises suction nozzle and runner parts, it is characterized in that:
One housing that is constituted by last main component and following main component is set;
On the top of housing, inverted cone shape medicated powder storage capsule is set;
In the upper periphery of housing, the manual rotating part of a ring-type is set;
Outer surface on housing top is provided with rotating slideway, and in the inboard of the manual rotating part of ring-type, correspondence is provided with slide block;
Between manual rotating part of ring-type and housing top, first elastomeric element is set;
End in described rotating slideway is provided with air inlet;
In the inside of housing, the runner parts are set;
The outside at housing is provided with suction nozzle, in the outside of suction nozzle, the suction nozzle cover is set;
The head end of described runner parts is connected with the air inlet gas circuit, and the end of runner parts is connected with the suction nozzle gas circuit, and the horizontal position at the runner parts is provided with feeding opening;
Below inverted cone shape medicated powder storage capsule, the administration gauge assembly is set;
Described runner parts gas circuit successively connect air inlet, administration gauge assembly and suction nozzle.
2. according to the described dry powder doser of claim 1, it is characterized in that described rotating slideway comprises upper and lower rotating slideway arranged side by side and first, second hoistway that is connected upper and lower rotating slideway head, end; The manual rotating part of described ring-type can be done the rotation in the predetermined angle and the lifting/lowering of assigned address on last main component under the guiding/restriction/effect of last/following rotating slideway, the first/the second hoistway, slide block and first elastomeric element.
3. according to the described dry powder doser of claim 2, it is characterized in that described predetermined angle is 120 degree; Described assigned address is head, the terminal position of upper and lower rotating slideway.
4. according to the described dry powder doser of claim 2, it is characterized in that air inlet being set at the described end of horizontal slideway down.
5. according to the described dry powder doser of claim 1, it is characterized in that described administration gauge assembly comprise the dosed administration dish that has central shaft, at the spring cup below the dosed administration dish, at second elastomeric element between main component and the spring cup down;
The head end of described central shaft, the top of running through main component is provided with, and the axle head end on main component top is provided with triangular key on central shaft passes;
In the centre of the manual rotating part of described ring-type, correspondence is provided with the triangle slotted eye;
Described center the tip of the axis is connected with following main component rotationally;
In the one side of described dosed administration dish towards inverted cone shape medicated powder storage capsule, three administration grooves are set, described administration groove is uniformly distributed along the circumference on the dosed administration dish;
The feeding opening position of described runner parts is with the corresponding setting of distribution circumference at three administration groove places;
In the upper end of described central shaft, engagement type clutch component is set.
6. according to the described dry powder doser of claim 5, it is characterized in that uniform on the circumference of described dosed administration dish three elastic positioning cards being set, the inboard of infra main component, correspondence is provided with three detents, described elastic positioning card and detent are complementary, in dosed administration dish rotating process, guarantee that the angle that each dosed administration dish rotates is 1/3rd of a circumference, give simultaneously one of user clear and definite be rotated in place signal.
7. according to the described dry powder doser of claim 5, it is characterized in that described engagement type clutch component comprises engaging tooth spare and following engaging tooth spare, described upper and lower engaging tooth spare is sleeved on the central shaft.
8. according to claim 1 or 5 described dry powder dosers, it is characterized in that described first elastomeric element or second elastomeric element are spring.
9. according to the described dry powder doser of claim 1, it is characterized in that top at described housing, dry component is set, described dry component comprise with the outlet of inverted cone shape medicated powder storage capsule in the same way opening tubular shell and be arranged in the graininess hygroscopic agent of housing.
10. according to claim 1 or 9 described dry powder dosers, it is characterized in that described dry component and longitudinal center's axis of the relative housing of inverted cone shape medicated powder storage capsule become 120 degree angle settings.
11. according to claim 1 or 9 described dry powder dosers, it is characterized in that the outlet of described dry component or inverted cone shape medicated powder storage capsule, with the corresponding setting of distribution circumference at three administration groove places.
12. according to the described dry powder doser of claim 1, it is characterized in that on described suction nozzle cover and the manual rotating part of ring-type, correspondence is provided with positioning convex and locating piece groove respectively, when the suction nozzle cover is in " covering " state, described positioning convex and locating piece groove cooperatively interact, stop between manual rotating part of ring-type and the last main component to rotate, constitute anti-misoperation frame for movement.
13. one kind according to the described dry powder doser of claim 1, it is characterized in that described dry powder doser finishes whole inhalation process according to following steps:
A, remove the suction nozzle cover downwards;
B, manually be rotated counterclockwise the manual rotating part of ring-type, to 120 degree extreme positions;
C, the manual rotating part of ring-type are upwards upspring automatically;
D, the manual manual rotating part of reverse rotation ring-type are to inverse limit 120 degree positions;
E, patient suck medicated powder through suction nozzle;
F, manually press the manual rotating part of ring-type;
G, cover the suction nozzle cover.
14., it is characterized in that described dry powder doser is finished whole " drying-confession medicine-administration " process according to following order according to the described dry powder doser of claim 13 in described whole inhalation process:
A1, remove the suction nozzle cover downwards, remove anti-error rotary machine restriction the manual rotating part of ring-type;
B1, manually be rotated counterclockwise the manual rotating part of ring-type, to 120 degree extreme positions, in the described administration gauge assembly the first administration groove of dosed administration dish accept inverted cone shape medicated powder storage capsule for medicine, realize quantitatively for medicine;
C1, the manual rotating part of ring-type are upwards upspring automatically, and air inlet open possesses the inhalation condition; Simultaneously, the triangular key of axle head end enters the triangle slotted eye at the manual rotating part of ring-type middle part among the described administration gauge assembly, for the rotation next time of dosed administration dish provides prerequisite;
D1, the manual manual rotating part of reverse rotation ring-type to inverse limit 120 degree positions, contain the feeding opening of the first administration groove alignment runner parts of medicated powder, finish for the medicine process, make the patient suck medicated powder and possess prerequisite;
E1, patient suck medicated powder through suction nozzle, and the gas that is used to deliver medicated powder enters the dry powder doser from air inlet, and longshore current road parts are sent into patient oral cavity with the medicated powder in the dosed administration dish first administration groove through suction nozzle to feeding opening, finish the administration process;
F1, manually press the manual rotating part of ring-type, the second administration groove and the dry component position alignment of dosed administration dish in the described administration gauge assembly are accepted dryly, carry out the preparation in advance that next time supplies medicine;
G1, cover the suction nozzle cover, recover anti-error rotary machine restriction the manual rotating part of ring-type.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110156768.4A CN102228725B (en) | 2011-06-13 | 2011-06-13 | Dry powder administration device |
| PCT/CN2012/076647 WO2012171443A1 (en) | 2011-06-13 | 2012-06-08 | Dry powder drug administration device |
| US14/125,936 US9750901B2 (en) | 2011-06-13 | 2012-06-08 | Dry powder drug-dosing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110156768.4A CN102228725B (en) | 2011-06-13 | 2011-06-13 | Dry powder administration device |
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| CN102228725A true CN102228725A (en) | 2011-11-02 |
| CN102228725B CN102228725B (en) | 2015-04-22 |
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| CN201110156768.4A Active CN102228725B (en) | 2011-06-13 | 2011-06-13 | Dry powder administration device |
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| CN106075676A (en) * | 2016-08-08 | 2016-11-09 | 中山市美捷时包装制品有限公司 | A kind of drug administration mechanism of powder inhaler |
| CN106075676B (en) * | 2016-08-08 | 2022-06-21 | 中山市美捷时包装制品有限公司 | Administration mechanism of dry powder inhalation device |
| CN107213540A (en) * | 2017-07-24 | 2017-09-29 | 无锡圣马科技有限公司 | Medicine quantitative electric powder-spraying apparatus |
| CN110215580A (en) * | 2019-06-15 | 2019-09-10 | 汉义生物科技（北京）有限公司 | A metered dose inhaler |
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| CN115518246B (en) * | 2022-09-26 | 2025-08-19 | 万通(苏州)定量阀系统有限公司 | Dry powder quantitative drug feeder |
| CN118830394A (en) * | 2024-08-05 | 2024-10-25 | 吉林大学 | Cultivator S-shaped spring tooth based on bionic technology |
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Effective date of registration: 20231225 Address after: No. 1633 Selling New Highway, Xinqiao Town, Songjiang District, Shanghai, 201612 Patentee after: SHANGHAI XINHUANGHE PHARMACEUTICAL CO.,LTD. Address before: Room 213, Building 2, No. 563 Songtao Road, Zhangjiang High tech Park, Pudong New Area, Shanghai, March 2012 Patentee before: SHANGHAI XIUXIN CHENPON PHARMACEUTICAL TECHNOLOGY Co.,Ltd. |