CN112513089A - 抗cd73抗体、其抗原结合片段及应用 - Google Patents
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Abstract
提供抗CD73抗体、其抗原结合片段及应用。具体地，提供包含特定CDR区的鼠源、嵌合或人源化抗CD73抗体及其抗原结合片段。还提供包含所述抗CD73抗体或其抗原结合片段的药物组合物，以及其作为CD73相关疾病诊断剂和治疗药物的用途。
Description
PCT国内申请，说明书已公开。
Claims (26)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811337068 | 2018-11-12 | ||
| CN2018113370683 | 2018-11-12 | ||
| PCT/CN2019/117114 WO2020098599A1 (zh) | 2018-11-12 | 2019-11-11 | 抗cd73抗体、其抗原结合片段及应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112513089A true CN112513089A (zh) | 2021-03-16 |
Family
ID=70730768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980050242.2A Pending CN112513089A (zh) | 2018-11-12 | 2019-11-11 | 抗cd73抗体、其抗原结合片段及应用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220220218A1 (zh) |
| EP (1) | EP3882268A4 (zh) |
| JP (1) | JP2022509930A (zh) |
| KR (1) | KR20210093255A (zh) |
| CN (1) | CN112513089A (zh) |
| AU (1) | AU2019381219A1 (zh) |
| BR (1) | BR112021007902A2 (zh) |
| CA (1) | CA3118775A1 (zh) |
| MX (1) | MX2021005396A (zh) |
| TW (1) | TW202017945A (zh) |
| WO (1) | WO2020098599A1 (zh) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113045659A (zh) * | 2021-03-18 | 2021-06-29 | 上海近岸科技有限公司 | 抗cd73人源化抗体 |
| WO2023109962A1 (zh) * | 2021-12-17 | 2023-06-22 | 三生国健药业（上海）股份有限公司 | 结合人cd73的抗体、其制备方法和用途 |
| CN116813786A (zh) * | 2023-08-03 | 2023-09-29 | 贝达药业股份有限公司 | 抗cd73抗体及其应用 |
| CN116903744A (zh) * | 2022-08-12 | 2023-10-20 | 南京蓬勃生物科技有限公司 | 抗cd73抗体或其抗原片段及其应用 |
| WO2023206242A1 (zh) * | 2022-04-28 | 2023-11-02 | 江苏中新医药有限公司 | 无钩状效应的抗人cd73单克隆抗体 |
| WO2024077774A1 (zh) * | 2022-10-13 | 2024-04-18 | 深圳市百士通科技开发有限公司 | 一种多功能重组抗体及其制备方法和应用 |
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| CR20220317A (es) | 2020-01-03 | 2022-09-02 | Incyte Corp | Anticuerpos anti-cd73 y usos de estos |
| KR20220137013A (ko) | 2020-01-03 | 2022-10-11 | 인사이트 코포레이션 | Cd73 억제제 및 a2a/a2b 아데노신 수용체 억제제 병용 요법 |
| CN116529265A (zh) * | 2020-12-11 | 2023-08-01 | 上海华奥泰生物药业股份有限公司 | Cd73的抗原结合蛋白及其应用 |
| JP7691720B2 (ja) * | 2021-02-24 | 2025-06-12 | 蘇州近岸蛋白質科技股▲ふん▼有限公司 | 抗ヒトｃｄ７３抗体およびその適用 |
| GB202105110D0 (en) * | 2021-04-09 | 2021-05-26 | Cancer Research Tech Ltd | Anti-CD73 antibodies |
| EP4494658A1 (en) * | 2022-03-14 | 2025-01-22 | Shanghai Huaota Biopharmaceutical Co., Ltd. | Antibody-drug conjugate and use thereof |
| JP2025512384A (ja) | 2022-04-13 | 2025-04-17 | ギリアード サイエンシーズ， インコーポレイテッド | Ｔｒｏｐ－２発現がんを治療するための併用療法 |
| WO2024040195A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
| WO2024249954A1 (en) | 2023-05-31 | 2024-12-05 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025076127A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
| WO2025179294A2 (en) | 2024-02-22 | 2025-08-28 | Capstan Therapeutics, Inc. | Immune engineering amplification |
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| EA202090956A3 (ru) * | 2014-11-21 | 2020-12-30 | Бристол-Майерс Сквибб Компани | Антитела к cd73 и их применения |
| EP3362475B1 (en) | 2015-10-12 | 2023-08-30 | Innate Pharma | Cd73 blocking agents |
| WO2017100670A1 (en) * | 2015-12-09 | 2017-06-15 | Corvus Pharmaceuticals, Inc. | Humanized anti-cd73 antibodies |
| CN109476740A (zh) | 2016-03-04 | 2019-03-15 | 百时美施贵宝公司 | 利用抗cd73抗体的联合治疗 |
| US10793636B2 (en) | 2016-07-11 | 2020-10-06 | Corvus Pharmaceuticals, Inc. | Anti-CD73 antibodies |
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- 2019-11-11 JP JP2021525680A patent/JP2022509930A/ja active Pending
- 2019-11-11 US US17/291,674 patent/US20220220218A1/en not_active Abandoned
- 2019-11-11 CA CA3118775A patent/CA3118775A1/en active Pending
- 2019-11-11 AU AU2019381219A patent/AU2019381219A1/en not_active Abandoned
- 2019-11-11 EP EP19885765.8A patent/EP3882268A4/en not_active Withdrawn
- 2019-11-11 BR BR112021007902A patent/BR112021007902A2/pt not_active Application Discontinuation
- 2019-11-11 MX MX2021005396A patent/MX2021005396A/es unknown
- 2019-11-11 WO PCT/CN2019/117114 patent/WO2020098599A1/zh not_active Ceased
- 2019-11-11 CN CN201980050242.2A patent/CN112513089A/zh active Pending
- 2019-11-11 KR KR1020217015118A patent/KR20210093255A/ko not_active Withdrawn
- 2019-11-12 TW TW108140993A patent/TW202017945A/zh unknown
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| CN107001472A (zh) * | 2014-11-10 | 2017-08-01 | 免疫医疗有限公司 | 对cd73具有特异性的结合分子及其用途 |
| WO2018137598A1 (en) * | 2017-01-24 | 2018-08-02 | I-Mab | Anti-cd73 antibodies and uses thereof |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113045659A (zh) * | 2021-03-18 | 2021-06-29 | 上海近岸科技有限公司 | 抗cd73人源化抗体 |
| WO2023109962A1 (zh) * | 2021-12-17 | 2023-06-22 | 三生国健药业（上海）股份有限公司 | 结合人cd73的抗体、其制备方法和用途 |
| WO2023206242A1 (zh) * | 2022-04-28 | 2023-11-02 | 江苏中新医药有限公司 | 无钩状效应的抗人cd73单克隆抗体 |
| CN116903744A (zh) * | 2022-08-12 | 2023-10-20 | 南京蓬勃生物科技有限公司 | 抗cd73抗体或其抗原片段及其应用 |
| CN116903744B (zh) * | 2022-08-12 | 2024-03-08 | 南京蓬勃生物科技有限公司 | 抗cd73抗体或其抗原片段及其应用 |
| WO2024077774A1 (zh) * | 2022-10-13 | 2024-04-18 | 深圳市百士通科技开发有限公司 | 一种多功能重组抗体及其制备方法和应用 |
| CN116813786A (zh) * | 2023-08-03 | 2023-09-29 | 贝达药业股份有限公司 | 抗cd73抗体及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3882268A4 (en) | 2022-08-17 |
| US20220220218A1 (en) | 2022-07-14 |
| EP3882268A1 (en) | 2021-09-22 |
| CA3118775A1 (en) | 2020-05-22 |
| KR20210093255A (ko) | 2021-07-27 |
| BR112021007902A2 (pt) | 2021-11-16 |
| JP2022509930A (ja) | 2022-01-25 |
| TW202017945A (zh) | 2020-05-16 |
| WO2020098599A1 (zh) | 2020-05-22 |
| MX2021005396A (es) | 2021-07-06 |
| AU2019381219A1 (en) | 2021-05-27 |
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