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EE04223B1 - Interferooni stabiilne vedelkompositsioon, mis sisaldab aminohappeid - Google Patents

Interferooni stabiilne vedelkompositsioon, mis sisaldab aminohappeid

Info

Publication number
EE04223B1
EE04223B1 EEP199900313A EE9900313A EE04223B1 EE 04223 B1 EE04223 B1 EE 04223B1 EE P199900313 A EEP199900313 A EE P199900313A EE 9900313 A EE9900313 A EE 9900313A EE 04223 B1 EE04223 B1 EE 04223B1
Authority
EE
Estonia
Prior art keywords
interferon
liquid
amino acids
liquid formulation
formulation containing
Prior art date
Application number
EEP199900313A
Other languages
English (en)
Other versions
EE9900313A (et
Inventor
D. Dibiasi Mary
Staples Mark
Chung Wen-Li
Scharin Eric
Original Assignee
Biogen, Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21875893&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE04223(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen, Incorporated filed Critical Biogen, Incorporated
Publication of EE9900313A publication Critical patent/EE9900313A/et
Publication of EE04223B1 publication Critical patent/EE04223B1/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Hospice & Palliative Care (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EEP199900313A 1996-12-24 1997-12-23 Interferooni stabiilne vedelkompositsioon, mis sisaldab aminohappeid EE04223B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3435396P 1996-12-24 1996-12-24
PCT/US1997/023817 WO1998028007A1 (en) 1996-12-24 1997-12-23 Stable liquid interferon formulations

Publications (2)

Publication Number Publication Date
EE9900313A EE9900313A (et) 2000-04-17
EE04223B1 true EE04223B1 (et) 2004-02-16

Family

ID=21875893

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP199900313A EE04223B1 (et) 1996-12-24 1997-12-23 Interferooni stabiilne vedelkompositsioon, mis sisaldab aminohappeid
EEP200300127A EE04266B1 (et) 1996-12-24 1997-12-23 Interferooni stabiilne vedelkompositsioon

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP200300127A EE04266B1 (et) 1996-12-24 1997-12-23 Interferooni stabiilne vedelkompositsioon

Country Status (27)

Country Link
EP (1) EP0948358B2 (et)
JP (5) JP4878664B2 (et)
KR (2) KR101042660B1 (et)
CN (2) CN1222315C (et)
AT (1) ATE270899T1 (et)
AU (1) AU738362B2 (et)
BG (2) BG65171B1 (et)
BR (1) BR9714434A (et)
CA (1) CA2275890C (et)
CZ (1) CZ300636B6 (et)
DE (1) DE69729880T3 (et)
DK (1) DK0948358T4 (et)
EA (1) EA002754B1 (et)
EE (2) EE04223B1 (et)
ES (1) ES2224290T5 (et)
HU (1) HU224222B1 (et)
IL (1) IL130524A (et)
IS (1) IS2070B (et)
MX (1) MX337876B (et)
NO (1) NO327844B1 (et)
NZ (2) NZ336548A (et)
PL (1) PL193447B1 (et)
PT (1) PT948358E (et)
SI (1) SI0948358T2 (et)
SK (1) SK284989B6 (et)
TR (1) TR199901968T2 (et)
WO (1) WO1998028007A1 (et)

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US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
AR034749A1 (es) * 2001-07-09 2004-03-17 Schering Ag Formulaciones de interferon beta humano
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US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
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CN115989239A (zh) * 2020-04-29 2023-04-18 瑷备恩有限公司 具有双重突变的人干扰素β变体和用于改善人干扰素β变体的稳定性的方法
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Also Published As

Publication number Publication date
JP4878664B2 (ja) 2012-02-15
DK0948358T4 (da) 2012-03-19
ES2224290T5 (es) 2012-03-12
SK284989B6 (sk) 2006-04-06
BR9714434A (pt) 2000-05-02
SI0948358T2 (sl) 2012-03-30
CZ300636B6 (cs) 2009-07-08
JP2001519770A (ja) 2001-10-23
EP0948358B2 (en) 2011-11-23
KR20070052363A (ko) 2007-05-21
NO993121D0 (no) 1999-06-23
KR20000069664A (ko) 2000-11-25
EP0948358B1 (en) 2004-07-14
EE9900313A (et) 2000-04-17
DE69729880D1 (de) 2004-08-19
EA199900597A1 (ru) 2000-02-28
PL334365A1 (en) 2000-02-28
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EP0948358A1 (en) 1999-10-13
HK1092048A1 (zh) 2007-02-02
NO993121L (no) 1999-08-24
MX337876B (es) 2016-03-22
EA002754B1 (ru) 2002-08-29
CA2275890A1 (en) 1998-07-02
EE04266B1 (et) 2004-04-15
PL193447B1 (pl) 2007-02-28
CN1733296A (zh) 2006-02-15
HK1025040A1 (en) 2000-11-03
NO327844B1 (no) 2009-10-05
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JP2014098029A (ja) 2014-05-29
BG65171B1 (bg) 2007-05-31
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JP2011068694A (ja) 2011-04-07
CA2275890C (en) 2011-11-01
TR199901968T2 (xx) 1999-12-21
DE69729880T2 (de) 2005-07-07
WO1998028007A1 (en) 1998-07-02
DE69729880T3 (de) 2012-05-10
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ES2224290T3 (es) 2005-03-01
EE200300127A (et) 2003-06-16
AU5619198A (en) 1998-07-17
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CN1733296B (zh) 2010-05-26
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IS5087A (is) 1999-06-21
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